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The map label for this gene is katE [H]

Identifier: 162146292

GI number: 162146292

Start: 466263

End: 467369

Strand: Direct

Name: katE [H]

Synonym: GDI_0467

Alternate gene names: 162146292

Gene position: 466263-467369 (Clockwise)

Preceding gene: 162146291

Following gene: 162146293

Centisome position: 11.82

GC content: 74.07

Gene sequence:

>1107_bases
ATGCCCGGACCACATGACAAGCCCGGCTCCTCGCGCGTCCCCCTCCGGCTTACGCCGGGCACGCTGGGCCGCCTGGGCGT
CATCGGGGCCGTGATGCTGGCCCTGTGCGGCGCCTTCGCCTGGGATGCGGGCGTCCTGTCCTCCCGCCGCCTGACGCAGG
GCGGGGTGATGGCGGCCCTGCGGGCCGTGGACGGGCTGCATCCCGGCTTTCGCCGCAACCATGCCAAGGGGCTGTGCGTC
ACCGGCTGGTTCCAGGCCAGCGGGCAGGCTGCGGCGCTCTCCACGGCCTCGCTCTTCCGTCCCGGGCGCGTGCCGGTGGT
CGGGCGGTTCGCGCTGGCGGGCGGCATGCCGTTCCAGCCGGACGCGCCGGCCAAGGTGCGCAGCATGGCGCTGCGCCTGA
TGCCGCCCGACGGGCAGGAATGGCGGATGGGAATCAACGATATTCCGGTCTTCGTCGCGCGCACCGCGCAGGAATTTCGC
GACCTGCTGCTGGCCACCCGGCCCGATCCCGCCACGGGCAAGCCCGATCCGGCCCGGATAGGGCCTTTCCTGTCCGCGCA
TCAGGCGGTGGCCACGGCGCTGGGGCGTGTCGCCGCCCGGCCGCTCACCTCCGGCTTCGGCGACGATACCTACTACAGCC
TGGACACGTTCCGCTTCGTCGATGCCGGCGGCGCCTCCGTGCCGGTCCGCTGGGCGATGGTGCCCCTCCAGCCGGTCCAG
CCGGCCGGGGCCGGCGGGGGGCCGGACTATCTGTTCGACGACCTGGCCGCCACGCTGCGCCGGCAGCCGCTGCAATGGCG
GCTGGTGGTGACGGTGGGTGATCCGTCCGATCCGACCGCCGACCCGACCCTGTCCTGGCCGTCCGGCCGCCGGCAGGTCG
ATGCCGGCCTGCTGACGCTGGACCGGGCCGAGAGCGAGGATGGCGGGCCCTGCACCGGCATCACCTACGACCCGGTGGTC
CTGCCGCCCGGCATCACCCTGTCGGACGATCCGATCCCGGCCGCGCGGTCGGCCGCCTATATGCGGTCCTTCATCCTGCG
CTCGGGCGAGGCCAAGCCGCCCAGCGCCGTAACGCCGGGCATGGCCGGGGCGGGGGGCGGATCATGA

Upstream 100 bases:

>100_bases
TCATCGCCAGATGCCGTAGGCTCCACAAAGGAAACCCGGCGGTCCGTCTGGCGTATGCAGCCGGGCGTCCATTTCGGACA
GCCCGCAAGTCGAGGCCACG

Downstream 100 bases:

>100_bases
CCCCCGTCATCCGCACCCGCGTCATCCGGTTTTCCGTCCTGGCCCGGGTCCTGCACTGGCTGATGGCCGTGATGATCCTG
GGCATGCTGTTCGTCGGTGC

Product: catalase

Products: H2O; O2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MPGPHDKPGSSRVPLRLTPGTLGRLGVIGAVMLALCGAFAWDAGVLSSRRLTQGGVMAALRAVDGLHPGFRRNHAKGLCV
TGWFQASGQAAALSTASLFRPGRVPVVGRFALAGGMPFQPDAPAKVRSMALRLMPPDGQEWRMGINDIPVFVARTAQEFR
DLLLATRPDPATGKPDPARIGPFLSAHQAVATALGRVAARPLTSGFGDDTYYSLDTFRFVDAGGASVPVRWAMVPLQPVQ
PAGAGGGPDYLFDDLAATLRRQPLQWRLVVTVGDPSDPTADPTLSWPSGRRQVDAGLLTLDRAESEDGGPCTGITYDPVV
LPPGITLSDDPIPAARSAAYMRSFILRSGEAKPPSAVTPGMAGAGGGS

Sequences:

>Translated_368_residues
MPGPHDKPGSSRVPLRLTPGTLGRLGVIGAVMLALCGAFAWDAGVLSSRRLTQGGVMAALRAVDGLHPGFRRNHAKGLCV
TGWFQASGQAAALSTASLFRPGRVPVVGRFALAGGMPFQPDAPAKVRSMALRLMPPDGQEWRMGINDIPVFVARTAQEFR
DLLLATRPDPATGKPDPARIGPFLSAHQAVATALGRVAARPLTSGFGDDTYYSLDTFRFVDAGGASVPVRWAMVPLQPVQ
PAGAGGGPDYLFDDLAATLRRQPLQWRLVVTVGDPSDPTADPTLSWPSGRRQVDAGLLTLDRAESEDGGPCTGITYDPVV
LPPGITLSDDPIPAARSAAYMRSFILRSGEAKPPSAVTPGMAGAGGGS
>Mature_367_residues
PGPHDKPGSSRVPLRLTPGTLGRLGVIGAVMLALCGAFAWDAGVLSSRRLTQGGVMAALRAVDGLHPGFRRNHAKGLCVT
GWFQASGQAAALSTASLFRPGRVPVVGRFALAGGMPFQPDAPAKVRSMALRLMPPDGQEWRMGINDIPVFVARTAQEFRD
LLLATRPDPATGKPDPARIGPFLSAHQAVATALGRVAARPLTSGFGDDTYYSLDTFRFVDAGGASVPVRWAMVPLQPVQP
AGAGGGPDYLFDDLAATLRRQPLQWRLVVTVGDPSDPTADPTLSWPSGRRQVDAGLLTLDRAESEDGGPCTGITYDPVVL
PPGITLSDDPIPAARSAAYMRSFILRSGEAKPPSAVTPGMAGAGGGS

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71998444, Length=300, Percent_Identity=25, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25147792, Length=294, Percent_Identity=22.7891156462585, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25151141, Length=294, Percent_Identity=22.7891156462585, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6 [C]

Molecular weight: Translated: 38414; Mature: 38283

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGPHDKPGSSRVPLRLTPGTLGRLGVIGAVMLALCGAFAWDAGVLSSRRLTQGGVMAAL
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RAVDGLHPGFRRNHAKGLCVTGWFQASGQAAALSTASLFRPGRVPVVGRFALAGGMPFQP
HHHHCCCCCHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEHHHCCCCCCCC
DAPAKVRSMALRLMPPDGQEWRMGINDIPVFVARTAQEFRDLLLATRPDPATGKPDPARI
CCCHHHHHHEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
GPFLSAHQAVATALGRVAARPLTSGFGDDTYYSLDTFRFVDAGGASVPVRWAMVPLQPVQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCEEEEEECCCCCC
PAGAGGGPDYLFDDLAATLRRQPLQWRLVVTVGDPSDPTADPTLSWPSGRRQVDAGLLTL
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
DRAESEDGGPCTGITYDPVVLPPGITLSDDPIPAARSAAYMRSFILRSGEAKPPSAVTPG
ECCCCCCCCCCCCCEECCEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
MAGAGGGS
CCCCCCCC
>Mature Secondary Structure 
PGPHDKPGSSRVPLRLTPGTLGRLGVIGAVMLALCGAFAWDAGVLSSRRLTQGGVMAAL
CCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RAVDGLHPGFRRNHAKGLCVTGWFQASGQAAALSTASLFRPGRVPVVGRFALAGGMPFQP
HHHHCCCCCHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEHHHCCCCCCCC
DAPAKVRSMALRLMPPDGQEWRMGINDIPVFVARTAQEFRDLLLATRPDPATGKPDPARI
CCCHHHHHHEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
GPFLSAHQAVATALGRVAARPLTSGFGDDTYYSLDTFRFVDAGGASVPVRWAMVPLQPVQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCEEEEEECCCCCC
PAGAGGGPDYLFDDLAATLRRQPLQWRLVVTVGDPSDPTADPTLSWPSGRRQVDAGLLTL
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
DRAESEDGGPCTGITYDPVVLPPGITLSDDPIPAARSAAYMRSFILRSGEAKPPSAVTPG
ECCCCCCCCCCCCCEECCEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
MAGAGGGS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: Hydrogen peroxide [C]

Specific reaction: (2) Hydrogen peroxide --> (2) H2O + O2 [C]

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]