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The map label for this gene is hesB [C]

Identifier: 162146271

GI number: 162146271

Start: 442813

End: 443133

Strand: Direct

Name: hesB [C]

Synonym: GDI_0446

Alternate gene names: 162146271

Gene position: 442813-443133 (Clockwise)

Preceding gene: 162146270

Following gene: 162146272

Centisome position: 11.23

GC content: 60.12

Gene sequence:

>321_bases
ATGATTGAGATGACCCCCAGCGCGTGTGAGGCGGTACGCGCGGCCATCGCCGGTGCAGCGACCCCGGTCGAGGGAATCCG
GATCATGGTCGAATCCGGTGGATGCTCGGGTTTCAAATACATGATGGGCCTGGTCGCGGCGCCCGAACCCTCGGACGTCG
TGGTTGACATCGACGGCGTCAAGGTCTTCGTCGATGCCGAAAGCGGGCCACATCTGCAGGGCACCAAGGTCGATTTCGTG
GTGACGCTGGAACAGTCGGGCTTCTCGTTCGACAATCCGAATGCGGCATCGAAATGTTCCTGCGGAAAGTCCTTTAACTG
A

Upstream 100 bases:

>100_bases
AGGACAGCCCCCGGAAAATAACCTCGGCCTTCTCTTTTGTCGTGGCACGCGGATTGCGTGGTTTCCGTGCGGAAGACATT
CGCGGGAAAAGGAGTTCACG

Downstream 100 bases:

>100_bases
ACTGTCGCGGCAGGGTCGGGCGTTGACGGAGGGAAATACAGATGTGGGAATATTCCGATAAGGTAAAGGACTACTTCTTC
AATCCCAAGAACGCCGGCGT

Product: hesB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MIEMTPSACEAVRAAIAGAATPVEGIRIMVESGGCSGFKYMMGLVAAPEPSDVVVDIDGVKVFVDAESGPHLQGTKVDFV
VTLEQSGFSFDNPNAASKCSCGKSFN

Sequences:

>Translated_106_residues
MIEMTPSACEAVRAAIAGAATPVEGIRIMVESGGCSGFKYMMGLVAAPEPSDVVVDIDGVKVFVDAESGPHLQGTKVDFV
VTLEQSGFSFDNPNAASKCSCGKSFN
>Mature_106_residues
MIEMTPSACEAVRAAIAGAATPVEGIRIMVESGGCSGFKYMMGLVAAPEPSDVVVDIDGVKVFVDAESGPHLQGTKVDFV
VTLEQSGFSFDNPNAASKCSCGKSFN

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=105, Percent_Identity=34.2857142857143, Blast_Score=71, Evalue=1e-13,
Organism=Homo sapiens, GI160420328, Length=84, Percent_Identity=42.8571428571429, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=40, Blast_Score=80, Evalue=2e-17,
Organism=Escherichia coli, GI1787974, Length=104, Percent_Identity=37.5, Blast_Score=79, Evalue=4e-17,
Organism=Escherichia coli, GI1786351, Length=104, Percent_Identity=37.5, Blast_Score=72, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24642263, Length=105, Percent_Identity=34.2857142857143, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 10949; Mature: 10949

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEMTPSACEAVRAAIAGAATPVEGIRIMVESGGCSGFKYMMGLVAAPEPSDVVVDIDGV
CCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHEECCCCCCCEEEEECCE
KVFVDAESGPHLQGTKVDFVVTLEQSGFSFDNPNAASKCSCGKSFN
EEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIEMTPSACEAVRAAIAGAATPVEGIRIMVESGGCSGFKYMMGLVAAPEPSDVVVDIDGV
CCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHEECCCCCCCEEEEECCE
KVFVDAESGPHLQGTKVDFVVTLEQSGFSFDNPNAASKCSCGKSFN
EEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157954; 12597275 [H]