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The map label for this gene is tktB [C]

Identifier: 162146073

GI number: 162146073

Start: 251889

End: 253955

Strand: Direct

Name: tktB [C]

Synonym: GDI_0241

Alternate gene names: 162146073

Gene position: 251889-253955 (Clockwise)

Preceding gene: 162146070

Following gene: 162146074

Centisome position: 6.39

GC content: 69.42

Gene sequence:

>2067_bases
GTGCCGGCCACGCGACCGTGGCCGATGAATGCCGTCCGGACCCGGTCCGGCGCGTGTGCAGCACACAGGAGACACCAGAT
GCTGACAGTCGAGCAGGCCGTGCAGGCCAAGGCCATCGCGTTGGGAAAACTGTCCGTTCGCGCCACCACCGCCGCAAAAG
CCGGCCATCCGACCACGGCTTTGTCGCTGACCCACCTGGTGACGGAACTGTTGTATCGCATCATGCGATGGGACCCGGCC
CATCCCCGGGCCCCGGGGTCCGATCGGCTGGTCCTGTCGGAAGGTCATGCGGTGCCCATCATCTACGCGGCCTGCGCGGA
CCTGGGGGTGACCATCACGCCCCACGGCAATGCCCGCCCGATGACGCAGGACGACCTGATGGCGCTGCGCGACATCGACA
GCCCCGTGGACGGCCATCCCAATCCCGAAATCGGTTTTCCCTTCTTCGACGCGGCCACCGGCTCGCTGGGGCAGGGGCTG
TCGGTCGCGGCCGGCCTGGCCGCCGCCGCCCGCCTGGATGGGATCGACAAGACGATCTACTGCATCATCGGGGACGGGGA
ATCGCGCGAGGGGCAGATCTGGGAAGCGATGGATTTCATCGCCGACCACGGCCTGACCAACGTCGTCGCGATCTTCAACT
GCAACACCCTGGCGCAGAGCGACTATGTCTCGCCCGCGCAGGACTGGGTGCACCTGCAGCACAAGGCCGAGGCCTTCGGC
TGGACCGCCCTGGCCATTGACGGGCACGATCCGGCCCGGATCGACGACGCGTTGCGCAACCGCGCGTCCCTGGCCAAGGG
CCGGCCGCTCTGTATCGTCGCCCGCACCGTCAAGGGTTGGGGCGTTCCCGACCTGGGCGGGATGGGCCACCACGGAACGC
CGGTCAAGCAGGACCAGCTCACCGCCGCGCTGGCGGCGCTGGACCACATGGCGCGGGAATACGGCGTGGACAGCGTCTTT
CCGGACGACGTTGAAAAACTGCTGCGGATCACGCCCCCGCCCGACGTTCCGGTCCAGCCTGCCCCCGTCGCGGCGCCGGC
ATCGCTGGGCACGGTGGCGCATGACAACGGGACGATCGCCGCCGCGCTGCGCGACAAGAAGATGATGTCGCCCCGCCGCG
CCTTCGGGACCGCGCTCAAGGCGCTGGGGGCCGCCAACCCCCAGATCGTCGCGCTGGATGCCGACGTGAAGAATTCGACC
TACGCCCAGGATTTCGCCGACGCCTTCCCCGACCGGTATTTCGAATCCCGGATCGGCGAACAGAACATGGTCTCGGCGGC
GGCGGGGCTGGCCGGCGGCGGCAAGATCCCGTTCGTCAGCACGTTCGGCCGCTTCCTGGAACGGGCCTTCGACCAGATCG
AAATGGCGATCATCGGCGGCGCCGACCTGAAGCTGGTGGGCACCCATATCGGCGTGACCCTGGCCTCGGACGGTCCCAGC
CAGATGGCGCTGGCGGACGTGGCCTTCATGCGCGCCTTCGCCCATGTGGGTGACAAGCGCGGCAACCCGGCGGTCAGGGT
GCTGACGCCCAGCGACGGGGTCAGCGCCTATGCCCTCGTCCTGGCCATGGCCGAATCCTCCGGCGCCTGCTACCTGCGCG
CGGTGCGGGGGGACCTGCCGATCCTCTATCCCGAAGGGGAAAAATTCCCCCTCGGCGGCCACAAGGTCGTGCGGCAGGCC
GACCCGGCGGGCGACGGTGCCGCGCTGGTGTTCGTGGCATCGGGCTACATGGTGCATAGCTGCCTGAAGGCGGCGCGGAT
CCTGGAACAGGACGGCGTCCGCACGGCGGTGGTGGACGCCTATTCCCTGCCGGCGGACGTGCCCGCCATCCTGGCCCTGG
CCGGGAAGGGCGGCCAGGTCGTGACCGTCGAGGACAATTACGTCGGCGGCCTGGGCAGCGAACTGGCCGAAGGCGCGGGC
ACGATCCCGGACGCCCCCCCGATCCACCCGCTGACCGTGACGCGGATTCCCAAGAGCGGCCGGTCGGCCGACGACGTCCT
GCACTATGTCGGCCTGGGGGTCGAGGATATCGTGGCGGCGGCCAGGGAGTACCTGCCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGGCCCCGTGTCCGTGCGCCGTTTCCCCAATTTTTAGGGAAACCTTCCGCGGGCGCCTGTCGTTCCAACTCGACACATCC
GGGGGGATGCGTCCGTCCCC

Downstream 100 bases:

>100_bases
TCGGAGCCCGCGCCATGTCCGACTACATCCTCTATTACTGGTCCGTGCCGTTCCGGGGCCAGTTCGTGCGCGCCGTCCTG
GCCCATGCCGGCAGAAGCTG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MPATRPWPMNAVRTRSGACAAHRRHQMLTVEQAVQAKAIALGKLSVRATTAAKAGHPTTALSLTHLVTELLYRIMRWDPA
HPRAPGSDRLVLSEGHAVPIIYAACADLGVTITPHGNARPMTQDDLMALRDIDSPVDGHPNPEIGFPFFDAATGSLGQGL
SVAAGLAAAARLDGIDKTIYCIIGDGESREGQIWEAMDFIADHGLTNVVAIFNCNTLAQSDYVSPAQDWVHLQHKAEAFG
WTALAIDGHDPARIDDALRNRASLAKGRPLCIVARTVKGWGVPDLGGMGHHGTPVKQDQLTAALAALDHMAREYGVDSVF
PDDVEKLLRITPPPDVPVQPAPVAAPASLGTVAHDNGTIAAALRDKKMMSPRRAFGTALKALGAANPQIVALDADVKNST
YAQDFADAFPDRYFESRIGEQNMVSAAAGLAGGGKIPFVSTFGRFLERAFDQIEMAIIGGADLKLVGTHIGVTLASDGPS
QMALADVAFMRAFAHVGDKRGNPAVRVLTPSDGVSAYALVLAMAESSGACYLRAVRGDLPILYPEGEKFPLGGHKVVRQA
DPAGDGAALVFVASGYMVHSCLKAARILEQDGVRTAVVDAYSLPADVPAILALAGKGGQVVTVEDNYVGGLGSELAEGAG
TIPDAPPIHPLTVTRIPKSGRSADDVLHYVGLGVEDIVAAAREYLPAA

Sequences:

>Translated_688_residues
MPATRPWPMNAVRTRSGACAAHRRHQMLTVEQAVQAKAIALGKLSVRATTAAKAGHPTTALSLTHLVTELLYRIMRWDPA
HPRAPGSDRLVLSEGHAVPIIYAACADLGVTITPHGNARPMTQDDLMALRDIDSPVDGHPNPEIGFPFFDAATGSLGQGL
SVAAGLAAAARLDGIDKTIYCIIGDGESREGQIWEAMDFIADHGLTNVVAIFNCNTLAQSDYVSPAQDWVHLQHKAEAFG
WTALAIDGHDPARIDDALRNRASLAKGRPLCIVARTVKGWGVPDLGGMGHHGTPVKQDQLTAALAALDHMAREYGVDSVF
PDDVEKLLRITPPPDVPVQPAPVAAPASLGTVAHDNGTIAAALRDKKMMSPRRAFGTALKALGAANPQIVALDADVKNST
YAQDFADAFPDRYFESRIGEQNMVSAAAGLAGGGKIPFVSTFGRFLERAFDQIEMAIIGGADLKLVGTHIGVTLASDGPS
QMALADVAFMRAFAHVGDKRGNPAVRVLTPSDGVSAYALVLAMAESSGACYLRAVRGDLPILYPEGEKFPLGGHKVVRQA
DPAGDGAALVFVASGYMVHSCLKAARILEQDGVRTAVVDAYSLPADVPAILALAGKGGQVVTVEDNYVGGLGSELAEGAG
TIPDAPPIHPLTVTRIPKSGRSADDVLHYVGLGVEDIVAAAREYLPAA
>Mature_687_residues
PATRPWPMNAVRTRSGACAAHRRHQMLTVEQAVQAKAIALGKLSVRATTAAKAGHPTTALSLTHLVTELLYRIMRWDPAH
PRAPGSDRLVLSEGHAVPIIYAACADLGVTITPHGNARPMTQDDLMALRDIDSPVDGHPNPEIGFPFFDAATGSLGQGLS
VAAGLAAAARLDGIDKTIYCIIGDGESREGQIWEAMDFIADHGLTNVVAIFNCNTLAQSDYVSPAQDWVHLQHKAEAFGW
TALAIDGHDPARIDDALRNRASLAKGRPLCIVARTVKGWGVPDLGGMGHHGTPVKQDQLTAALAALDHMAREYGVDSVFP
DDVEKLLRITPPPDVPVQPAPVAAPASLGTVAHDNGTIAAALRDKKMMSPRRAFGTALKALGAANPQIVALDADVKNSTY
AQDFADAFPDRYFESRIGEQNMVSAAAGLAGGGKIPFVSTFGRFLERAFDQIEMAIIGGADLKLVGTHIGVTLASDGPSQ
MALADVAFMRAFAHVGDKRGNPAVRVLTPSDGVSAYALVLAMAESSGACYLRAVRGDLPILYPEGEKFPLGGHKVVRQAD
PAGDGAALVFVASGYMVHSCLKAARILEQDGVRTAVVDAYSLPADVPAILALAGKGGQVVTVEDNYVGGLGSELAEGAGT
IPDAPPIHPLTVTRIPKSGRSADDVLHYVGLGVEDIVAAAREYLPAA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=661, Percent_Identity=36.1573373676248, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI4507521, Length=661, Percent_Identity=36.1573373676248, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI133778974, Length=666, Percent_Identity=33.6336336336336, Blast_Score=339, Evalue=5e-93,
Organism=Homo sapiens, GI225637459, Length=672, Percent_Identity=30.0595238095238, Blast_Score=297, Evalue=3e-80,
Organism=Homo sapiens, GI225637461, Length=672, Percent_Identity=29.6130952380952, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI225637463, Length=556, Percent_Identity=32.1942446043165, Blast_Score=277, Evalue=3e-74,
Organism=Escherichia coli, GI1788808, Length=615, Percent_Identity=25.5284552845528, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI48994911, Length=616, Percent_Identity=26.1363636363636, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1786622, Length=506, Percent_Identity=25.098814229249, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17539652, Length=650, Percent_Identity=36.1538461538462, Blast_Score=370, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6325331, Length=605, Percent_Identity=26.1157024793388, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319593, Length=668, Percent_Identity=23.502994011976, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45551847, Length=649, Percent_Identity=35.1309707241911, Blast_Score=355, Evalue=6e-98,
Organism=Drosophila melanogaster, GI45550715, Length=649, Percent_Identity=35.1309707241911, Blast_Score=355, Evalue=6e-98,
Organism=Drosophila melanogaster, GI24666278, Length=640, Percent_Identity=35.46875, Blast_Score=353, Evalue=3e-97,
Organism=Drosophila melanogaster, GI24645119, Length=624, Percent_Identity=34.9358974358974, Blast_Score=333, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72210; Mature: 72079

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATRPWPMNAVRTRSGACAAHRRHQMLTVEQAVQAKAIALGKLSVRATTAAKAGHPTTA
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECEEEEEEHHHCCCCCHHH
LSLTHLVTELLYRIMRWDPAHPRAPGSDRLVLSEGHAVPIIYAACADLGVTITPHGNARP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHCCEEECCCCCCCC
MTQDDLMALRDIDSPVDGHPNPEIGFPFFDAATGSLGQGLSVAAGLAAAARLDGIDKTIY
CCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
CIIGDGESREGQIWEAMDFIADHGLTNVVAIFNCNTLAQSDYVSPAQDWVHLQHKAEAFG
EEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHCC
WTALAIDGHDPARIDDALRNRASLAKGRPLCIVARTVKGWGVPDLGGMGHHGTPVKQDQL
EEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
TAALAALDHMAREYGVDSVFPDDVEKLLRITPPPDVPVQPAPVAAPASLGTVAHDNGTIA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEE
AALRDKKMMSPRRAFGTALKALGAANPQIVALDADVKNSTYAQDFADAFPDRYFESRIGE
EEEHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
QNMVSAAAGLAGGGKIPFVSTFGRFLERAFDQIEMAIIGGADLKLVGTHIGVTLASDGPS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEEEEEEEECCCCC
QMALADVAFMRAFAHVGDKRGNPAVRVLTPSDGVSAYALVLAMAESSGACYLRAVRGDLP
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
ILYPEGEKFPLGGHKVVRQADPAGDGAALVFVASGYMVHSCLKAARILEQDGVRTAVVDA
EECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEH
YSLPADVPAILALAGKGGQVVTVEDNYVGGLGSELAEGAGTIPDAPPIHPLTVTRIPKSG
HCCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCCC
RSADDVLHYVGLGVEDIVAAAREYLPAA
CCHHHHHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PATRPWPMNAVRTRSGACAAHRRHQMLTVEQAVQAKAIALGKLSVRATTAAKAGHPTTA
CCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECEEEEEEHHHCCCCCHHH
LSLTHLVTELLYRIMRWDPAHPRAPGSDRLVLSEGHAVPIIYAACADLGVTITPHGNARP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHCCEEECCCCCCCC
MTQDDLMALRDIDSPVDGHPNPEIGFPFFDAATGSLGQGLSVAAGLAAAARLDGIDKTIY
CCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
CIIGDGESREGQIWEAMDFIADHGLTNVVAIFNCNTLAQSDYVSPAQDWVHLQHKAEAFG
EEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHCC
WTALAIDGHDPARIDDALRNRASLAKGRPLCIVARTVKGWGVPDLGGMGHHGTPVKQDQL
EEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
TAALAALDHMAREYGVDSVFPDDVEKLLRITPPPDVPVQPAPVAAPASLGTVAHDNGTIA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEE
AALRDKKMMSPRRAFGTALKALGAANPQIVALDADVKNSTYAQDFADAFPDRYFESRIGE
EEEHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
QNMVSAAAGLAGGGKIPFVSTFGRFLERAFDQIEMAIIGGADLKLVGTHIGVTLASDGPS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEEEEEEEECCCCC
QMALADVAFMRAFAHVGDKRGNPAVRVLTPSDGVSAYALVLAMAESSGACYLRAVRGDLP
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
ILYPEGEKFPLGGHKVVRQADPAGDGAALVFVASGYMVHSCLKAARILEQDGVRTAVVDA
EECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEH
YSLPADVPAILALAGKGGQVVTVEDNYVGGLGSELAEGAGTIPDAPPIHPLTVTRIPKSG
HCCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCCC
RSADDVLHYVGLGVEDIVAAAREYLPAA
CCHHHHHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]