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The map label for this gene is tetR [H]

Identifier: 162146062

GI number: 162146062

Start: 242559

End: 243266

Strand: Reverse

Name: tetR [H]

Synonym: GDI_0230

Alternate gene names: 162146062

Gene position: 243266-242559 (Counterclockwise)

Preceding gene: 162146066

Following gene: 162146061

Centisome position: 6.17

GC content: 67.94

Gene sequence:

>708_bases
ATGAGGGGCGCGAGTCCGCGTTCAAGGATTTATGGAGCGATGACACCAAAAAAAATCGACGGTGAACGGCGTGGCCGCGG
CCGGCCGCAATCCTTCGACCGGGACCAGGCCCTGTGCGCGGCCATGCGCCTGTTCTGGGATCGTGGCTATGAAGGCACCA
GCTTCGACGAACTGACGGCGGCGATGGGGATCAGCCCGTCGAGTTTCTACAACGCCTTCGGCAGCAAGGAGCAGTTGTAC
CAGGAGGCGACCGAGGCGTACCTGACCGCCTCGCGCGCGTGGTTCCTGGACATCCTGCAACAGGACGCCGACACGCGGAC
CGTTTTCCGGCACCTGATGGAAGCGGCAGCGACCGAGTTCACGCGCGAGGACCTGCCGGCGGGGTGCATGATCTCGGTGT
CCGGTACCCAGTGCGCGCCCGGCCAGGCCCGCCTGCGCGACCTGATGGCCCGCCAGCGCGCGCTGTCCGAGGCCGCGATG
GCCGACCGCCTGCGCCAGGGCGTGGCGGATGGCGACATGCCGGCGGATACGGATGCCGCGGGGCTGGCGGCCTTCTTCAG
TTCGCTGGCACGCGGGATGGCGGTGCAGGCGCGCGACGGTGCGTCGCGGGACAGACTGCTGGACATCGCACGGATCGGCA
TGCAGGCCTGGCCCACGCGACAGGACACGGTCCCTTGTCCCACCCGTGACGCGTTCATAACTCCATAG

Upstream 100 bases:

>100_bases
TGGACCTGTCTGCTCGGGCGGGAACGACGCGCGTTCCTCATGCCCGGATTGCGGAAACGAAAGGCTTACAATTTGGAGTG
ACTGCTCCAAGATACGGGAT

Downstream 100 bases:

>100_bases
GGCAGACGATCAGCCAACGGGGACGCACATGAAGATCGGCATTATCGGCGCCGGCCACATTGGCGGCGCACTGACCCGGC
GCCTGACGGCGCTGGGCCAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRGASPRSRIYGAMTPKKIDGERRGRGRPQSFDRDQALCAAMRLFWDRGYEGTSFDELTAAMGISPSSFYNAFGSKEQLY
QEATEAYLTASRAWFLDILQQDADTRTVFRHLMEAAATEFTREDLPAGCMISVSGTQCAPGQARLRDLMARQRALSEAAM
ADRLRQGVADGDMPADTDAAGLAAFFSSLARGMAVQARDGASRDRLLDIARIGMQAWPTRQDTVPCPTRDAFITP

Sequences:

>Translated_235_residues
MRGASPRSRIYGAMTPKKIDGERRGRGRPQSFDRDQALCAAMRLFWDRGYEGTSFDELTAAMGISPSSFYNAFGSKEQLY
QEATEAYLTASRAWFLDILQQDADTRTVFRHLMEAAATEFTREDLPAGCMISVSGTQCAPGQARLRDLMARQRALSEAAM
ADRLRQGVADGDMPADTDAAGLAAFFSSLARGMAVQARDGASRDRLLDIARIGMQAWPTRQDTVPCPTRDAFITP
>Mature_235_residues
MRGASPRSRIYGAMTPKKIDGERRGRGRPQSFDRDQALCAAMRLFWDRGYEGTSFDELTAAMGISPSSFYNAFGSKEQLY
QEATEAYLTASRAWFLDILQQDADTRTVFRHLMEAAATEFTREDLPAGCMISVSGTQCAPGQARLRDLMARQRALSEAAM
ADRLRQGVADGDMPADTDAAGLAAFFSSLARGMAVQARDGASRDRLLDIARIGMQAWPTRQDTVPCPTRDAFITP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081833, Length=197, Percent_Identity=32.48730964467, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI87082397, Length=206, Percent_Identity=28.6407766990291, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25851; Mature: 25851

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGASPRSRIYGAMTPKKIDGERRGRGRPQSFDRDQALCAAMRLFWDRGYEGTSFDELTA
CCCCCCHHHHCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
AMGISPSSFYNAFGSKEQLYQEATEAYLTASRAWFLDILQQDADTRTVFRHLMEAAATEF
HHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TREDLPAGCMISVSGTQCAPGQARLRDLMARQRALSEAAMADRLRQGVADGDMPADTDAA
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
GLAAFFSSLARGMAVQARDGASRDRLLDIARIGMQAWPTRQDTVPCPTRDAFITP
HHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRGASPRSRIYGAMTPKKIDGERRGRGRPQSFDRDQALCAAMRLFWDRGYEGTSFDELTA
CCCCCCHHHHCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
AMGISPSSFYNAFGSKEQLYQEATEAYLTASRAWFLDILQQDADTRTVFRHLMEAAATEF
HHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TREDLPAGCMISVSGTQCAPGQARLRDLMARQRALSEAAMADRLRQGVADGDMPADTDAA
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
GLAAFFSSLARGMAVQARDGASRDRLLDIARIGMQAWPTRQDTVPCPTRDAFITP
HHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]