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The map label for this gene is arpC [H]

Identifier: 162145978

GI number: 162145978

Start: 154999

End: 156519

Strand: Reverse

Name: arpC [H]

Synonym: GDI_0144

Alternate gene names: 162145978

Gene position: 156519-154999 (Counterclockwise)

Preceding gene: 162145980

Following gene: 162145977

Centisome position: 3.97

GC content: 65.35

Gene sequence:

>1521_bases
TTGCCACCCAATTTCCTGCCCCCTAGCCAGAGGCCAAAGCGGGTCGCCGCCGCATCACGCGCGGCCCGGCTGATTCTCGT
TGTCCTGGTGCCGGGCCTCACAGGCTGCACAGTCGGCCCGACCTACAAGGCTCCCCAGCCACCGGATGCCGCAACATTCG
GCGAAACCCGGTCGGAAACAGCGACCATAGCTTCGTCCAGCTCCCCGTATCAGGCCGCTGGAAAGCCAGGCTCCGACTGG
TGGCGTCTCTTTCACTCCCCTCGGCTGGACACCCTCGTCACAGAGGCACTCCAGAGCAACTGGTCGATCCAGGCGGCGCA
GGCCAACCTGCGCAAGGCCGCTGAGGGACTTCATGCCGCCCAGGGCAGCCTGATGCCCCAGATCGATGCCACCGGCACCG
AAGGACGACAGGAATACGGCGCCGCCTTGTTCGGTCCCTGGGCGTGGACCTTCCCGGCCTTCTCCGCCTATTCGGCCGGT
CTCGACGTTTCCTATGACCCCGATATTTTCGGTAGCAATCACCGGCTGATCCAGATGGTCGGCGCACAAAAGGATGCCGA
ACGGGAGCGCCGTGATGTCACGATGCTCCTGGTGGTCGGCGACACGGTCCTAACCGCCTTCGAAGCGGCCTCGACAGCAG
ACCAGATCGCCGTGATCCGGGGTGTGATCGACACCGACCGGGAAACGCTCCGGCTGGCAACGCTCGCCTGGCAGGCGGGC
AGGAGACCCCGACTGGATGTCGTGACGGCCGAAGCGCAGTTGGCGCACGACCAGTCTCTCCTGCCGCCGCTGATCAATGC
CCATGAAGCCGCGCGAACGACACTGGCCGTCCTGACCGGGCATTCGCCCGCCAACTGGACCGCACCGATCCTGACGCTCG
CCGATTTCAGCCTTCTGCCAGACATCCCTGTGGTCGTGCCCTCCGACCTTGTCCATGCCCGTCCGGATATCATCGGCGCC
GAAGCCATGATGCGCGCGACGAATGCCGAAATCGGTGCCCGGACGGCTGACCTGTATCCCCGCCTGACCCTCAGTGCGGC
CGCCGCTGCCGAAGGTCTGATGGGTGGCCCCGCCGGTGCGGCATGGCGTCTGATCGGCGGCGCTGCTCTGCCACTGTTCC
ATGGCGGCACCCTGAAGGCCCGGAAAAAACAGGCGGAAGAGGACTATCGGATCGCTTTCGATCACTACCAGTCAGTGGTC
ATCAATGGCTTTCGGGAGGTCGCCGATAGTCTGAACGGCCTGAAGAACGCCTCGACGGAACTGGACAACCAGCGGCAGGC
CCTGACCTCGGCCGATGACGCGCTGACCTTGAGCCAGGCCGGTTATCAGGCGGGCCGGGGAACCATCCTTCAGCCGATCA
ACGCCCGACGGCTCTTTCTGCTCGCGCGCCAGAACACAGTGCGGGCACAGACCGAGATGTTCCGTCAGACGGTGCGGATC
ATGGTGGCGACCGGCGGTGGACTCGCCGACTCCCACGTCACACCCGATCAGTGGCGATCCGTCCGGCTCGCGGCGCGATG
A

Upstream 100 bases:

>100_bases
CCCCCGTCATAAGCCTGTGTCTCGATAAGGCTGGCCTTTACTTCGTATGTACGTCTATGTTCGTATCATTGAGACTCGTT
CATGACGACCGGAGGCCGCC

Downstream 100 bases:

>100_bases
CCGGCATCTGATGCACGTTCGGCCTCCAATGTCCGGACTTTCCAGCCCTCTAGGTACGTATATCCGCGTATAACAATAAC
TTCGGGAGATATCTGTGCGA

Product: RND efflux system, outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MPPNFLPPSQRPKRVAAASRAARLILVVLVPGLTGCTVGPTYKAPQPPDAATFGETRSETATIASSSSPYQAAGKPGSDW
WRLFHSPRLDTLVTEALQSNWSIQAAQANLRKAAEGLHAAQGSLMPQIDATGTEGRQEYGAALFGPWAWTFPAFSAYSAG
LDVSYDPDIFGSNHRLIQMVGAQKDAERERRDVTMLLVVGDTVLTAFEAASTADQIAVIRGVIDTDRETLRLATLAWQAG
RRPRLDVVTAEAQLAHDQSLLPPLINAHEAARTTLAVLTGHSPANWTAPILTLADFSLLPDIPVVVPSDLVHARPDIIGA
EAMMRATNAEIGARTADLYPRLTLSAAAAAEGLMGGPAGAAWRLIGGAALPLFHGGTLKARKKQAEEDYRIAFDHYQSVV
INGFREVADSLNGLKNASTELDNQRQALTSADDALTLSQAGYQAGRGTILQPINARRLFLLARQNTVRAQTEMFRQTVRI
MVATGGGLADSHVTPDQWRSVRLAAR

Sequences:

>Translated_506_residues
MPPNFLPPSQRPKRVAAASRAARLILVVLVPGLTGCTVGPTYKAPQPPDAATFGETRSETATIASSSSPYQAAGKPGSDW
WRLFHSPRLDTLVTEALQSNWSIQAAQANLRKAAEGLHAAQGSLMPQIDATGTEGRQEYGAALFGPWAWTFPAFSAYSAG
LDVSYDPDIFGSNHRLIQMVGAQKDAERERRDVTMLLVVGDTVLTAFEAASTADQIAVIRGVIDTDRETLRLATLAWQAG
RRPRLDVVTAEAQLAHDQSLLPPLINAHEAARTTLAVLTGHSPANWTAPILTLADFSLLPDIPVVVPSDLVHARPDIIGA
EAMMRATNAEIGARTADLYPRLTLSAAAAAEGLMGGPAGAAWRLIGGAALPLFHGGTLKARKKQAEEDYRIAFDHYQSVV
INGFREVADSLNGLKNASTELDNQRQALTSADDALTLSQAGYQAGRGTILQPINARRLFLLARQNTVRAQTEMFRQTVRI
MVATGGGLADSHVTPDQWRSVRLAAR
>Mature_505_residues
PPNFLPPSQRPKRVAAASRAARLILVVLVPGLTGCTVGPTYKAPQPPDAATFGETRSETATIASSSSPYQAAGKPGSDWW
RLFHSPRLDTLVTEALQSNWSIQAAQANLRKAAEGLHAAQGSLMPQIDATGTEGRQEYGAALFGPWAWTFPAFSAYSAGL
DVSYDPDIFGSNHRLIQMVGAQKDAERERRDVTMLLVVGDTVLTAFEAASTADQIAVIRGVIDTDRETLRLATLAWQAGR
RPRLDVVTAEAQLAHDQSLLPPLINAHEAARTTLAVLTGHSPANWTAPILTLADFSLLPDIPVVVPSDLVHARPDIIGAE
AMMRATNAEIGARTADLYPRLTLSAAAAAEGLMGGPAGAAWRLIGGAALPLFHGGTLKARKKQAEEDYRIAFDHYQSVVI
NGFREVADSLNGLKNASTELDNQRQALTSADDALTLSQAGYQAGRGTILQPINARRLFLLARQNTVRAQTEMFRQTVRIM
VATGGGLADSHVTPDQWRSVRLAAR

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=494, Percent_Identity=24.2914979757085, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI2367348, Length=436, Percent_Identity=21.7889908256881, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 54238; Mature: 54107

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPNFLPPSQRPKRVAAASRAARLILVVLVPGLTGCTVGPTYKAPQPPDAATFGETRSET
CCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ATIASSSSPYQAAGKPGSDWWRLFHSPRLDTLVTEALQSNWSIQAAQANLRKAAEGLHAA
EEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
QGSLMPQIDATGTEGRQEYGAALFGPWAWTFPAFSAYSAGLDVSYDPDIFGSNHRLIQMV
CCCCCCCCCCCCCCCHHHHCCEEECCCHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEEEE
GAQKDAERERRDVTMLLVVGDTVLTAFEAASTADQIAVIRGVIDTDRETLRLATLAWQAG
CCCCHHHHHHCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RRPRLDVVTAEAQLAHDQSLLPPLINAHEAARTTLAVLTGHSPANWTAPILTLADFSLLP
CCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCC
DIPVVVPSDLVHARPDIIGAEAMMRATNAEIGARTADLYPRLTLSAAAAAEGLMGGPAGA
CCCEECCCHHHHCCCCCCCHHHHHHHHCCHHCCCHHHCCCCHHHHHHHHHHCCCCCCCCH
AWRLIGGAALPLFHGGTLKARKKQAEEDYRIAFDHYQSVVINGFREVADSLNGLKNASTE
HHHHHCCEECCEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LDNQRQALTSADDALTLSQAGYQAGRGTILQPINARRLFLLARQNTVRAQTEMFRQTVRI
HHHHHHHHHCCCCCEEHHHCCCCCCCCCEECCCCCCEEEEEECCCHHHHHHHHHHHHHEE
MVATGGGLADSHVTPDQWRSVRLAAR
EEEECCCCCCCCCCHHHHHCEEECCC
>Mature Secondary Structure 
PPNFLPPSQRPKRVAAASRAARLILVVLVPGLTGCTVGPTYKAPQPPDAATFGETRSET
CCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ATIASSSSPYQAAGKPGSDWWRLFHSPRLDTLVTEALQSNWSIQAAQANLRKAAEGLHAA
EEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
QGSLMPQIDATGTEGRQEYGAALFGPWAWTFPAFSAYSAGLDVSYDPDIFGSNHRLIQMV
CCCCCCCCCCCCCCCHHHHCCEEECCCHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEEEE
GAQKDAERERRDVTMLLVVGDTVLTAFEAASTADQIAVIRGVIDTDRETLRLATLAWQAG
CCCCHHHHHHCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RRPRLDVVTAEAQLAHDQSLLPPLINAHEAARTTLAVLTGHSPANWTAPILTLADFSLLP
CCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCC
DIPVVVPSDLVHARPDIIGAEAMMRATNAEIGARTADLYPRLTLSAAAAAEGLMGGPAGA
CCCEECCCHHHHCCCCCCCHHHHHHHHCCHHCCCHHHCCCCHHHHHHHHHHCCCCCCCCH
AWRLIGGAALPLFHGGTLKARKKQAEEDYRIAFDHYQSVVINGFREVADSLNGLKNASTE
HHHHHCCEECCEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LDNQRQALTSADDALTLSQAGYQAGRGTILQPINARRLFLLARQNTVRAQTEMFRQTVRI
HHHHHHHHHCCCCCEEHHHCCCCCCCCCEECCCCCCEEEEEECCCHHHHHHHHHHHHHEE
MVATGGGLADSHVTPDQWRSVRLAAR
EEEECCCCCCCCCCHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]