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The map label for this gene is katA [H]

Identifier: 162145915

GI number: 162145915

Start: 90932

End: 92401

Strand: Reverse

Name: katA [H]

Synonym: GDI_0079

Alternate gene names: 162145915

Gene position: 92401-90932 (Counterclockwise)

Preceding gene: 162145916

Following gene: 162145914

Centisome position: 2.34

GC content: 60.07

Gene sequence:

>1470_bases
ATGACGACTGAGCAGACAACAGCATATCATACGACGGAGTCCGGCATTCCCGTCTCCAGCGACGAGCATTCGCTGACTGT
CGGTGCCGATGGCCCGATCCTGCTGCACGATCACTACCTGATCGAGCAGATAGCGGCATTCAATCGTGAGATGATCCCCG
ACCGTCAGCCCCATGCCAAAGGCAGCGGCGCGTTCGGTCGGTTCGAAGTCACCCACGATGTCAGCCGGTATACCTGCGCC
AAATTCCTGCAACCGGGCGCGAGGACGGAGGTCGTCGCGCGCTTCTCGACCGTGGCGGGAGAGGCCGGAAGCCCGGATAC
GTGGCGCGATCCGCGTGGATTTGCCCTGAAATTCTATACGGAGGACGGCAATTTCGACATGGTCGGCAATAACACGCCGG
TCTTCTTCGTGCGCGATCCGCTGAAATTCCAGCATTTCATCCATTCGCAGAAGCGCCGTGTGGATAACGGCCTGCGCGAC
AACGACATGCAGTGGGATTTCTGGACATTGAGCCCGGAGACCGCGCATCAGGTGACATGGCTGATGGGCGACCGTGGCAT
CCCGGCAAGCTGGCGCCACATGGATGGGTTTTCCAGCCACACCTATCTATGGGTGAATGCGGCTGGCGAGCGGTTCTGGG
TGAAGTATCACTTCAAGACCGATCAGGGCATCAAGTGCCTGACGCAGGAGCAGGCAGGTCAGCTTGCGGGCGCGGATGCC
GATTATCACCGGCGCGATCTCTATACGGCGATCAAACGTGGCGAGCATCCGAGCTGGACGCTCAAGATGCAGATCATGCC
GTATGAGGACGCGAAGACCTATCGCATCAACCCGTTCGACCTGACCAAGGTCTGGCCGCAGGGCGAATATCCGCTGATTG
AGGTCGGCAAGCTGACGCTCGACCGGAACCCGACGGATTTCCACTCCCAGATCGAGCAGGTCGCATTCGAGCCGAACAAT
TTCGTGCCGGGAACCGGACTGTCACCCGACAAGATGCTGCTGGGGCGTTCGTTCGCCTATGCGGATGCACATCGGGCGCG
GTTGGGCGTGAACTATAAGCAGATTCCGGTCAACGCGCCGAAATGTCCGGTCCATGGCTACACCAAGGGGGGCGCCATGC
GGATGCGTGACGCGCATGACCCGGCCTATGTGCCAAACTCCAAAGGTGGTCCCGCGGCTGACAGGCAGCGTTTCCCCGAG
AATGCGGTCTGGGCAGCGGACGGCGAATTCGTACGTGCGGCGTATACGCTTCGGCCGGACGATGACGATTTCAGCCAGGC
CCATGCGCTGGTCAACCGCGTGATGGACGATGCGGCGCGTGACCGTCTGGTGAGCAATATCGTCGGGCATGTGTTGCAGG
GCGTTGAGGAACCTGTTTTGTCGAGGGTGTTCGAATACTGGTCGAAGATCGACGAGACGATCGGAGCACGGGTAAAGGAA
GGTGTGCTCGCCGAACGAGCAGGAGATTAA

Upstream 100 bases:

>100_bases
ATTGCCCTGCGCGCGACGCTTGGAAAATCGCGCCGACACGTTTAGAAACAGAATGTCAGCGCGGATTCACATTCAGAATA
ACCGTTCGAAGGAAACTGTC

Downstream 100 bases:

>100_bases
GATTGTTTGGCGTTCATCCCTACGTCATAAATTCGGCCTGAGGAAACAACCCCGCAGATATCCGCGCTACGGTCATCTGC
TTGGGAGACTCCACGTCGGG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MTTEQTTAYHTTESGIPVSSDEHSLTVGADGPILLHDHYLIEQIAAFNREMIPDRQPHAKGSGAFGRFEVTHDVSRYTCA
KFLQPGARTEVVARFSTVAGEAGSPDTWRDPRGFALKFYTEDGNFDMVGNNTPVFFVRDPLKFQHFIHSQKRRVDNGLRD
NDMQWDFWTLSPETAHQVTWLMGDRGIPASWRHMDGFSSHTYLWVNAAGERFWVKYHFKTDQGIKCLTQEQAGQLAGADA
DYHRRDLYTAIKRGEHPSWTLKMQIMPYEDAKTYRINPFDLTKVWPQGEYPLIEVGKLTLDRNPTDFHSQIEQVAFEPNN
FVPGTGLSPDKMLLGRSFAYADAHRARLGVNYKQIPVNAPKCPVHGYTKGGAMRMRDAHDPAYVPNSKGGPAADRQRFPE
NAVWAADGEFVRAAYTLRPDDDDFSQAHALVNRVMDDAARDRLVSNIVGHVLQGVEEPVLSRVFEYWSKIDETIGARVKE
GVLAERAGD

Sequences:

>Translated_489_residues
MTTEQTTAYHTTESGIPVSSDEHSLTVGADGPILLHDHYLIEQIAAFNREMIPDRQPHAKGSGAFGRFEVTHDVSRYTCA
KFLQPGARTEVVARFSTVAGEAGSPDTWRDPRGFALKFYTEDGNFDMVGNNTPVFFVRDPLKFQHFIHSQKRRVDNGLRD
NDMQWDFWTLSPETAHQVTWLMGDRGIPASWRHMDGFSSHTYLWVNAAGERFWVKYHFKTDQGIKCLTQEQAGQLAGADA
DYHRRDLYTAIKRGEHPSWTLKMQIMPYEDAKTYRINPFDLTKVWPQGEYPLIEVGKLTLDRNPTDFHSQIEQVAFEPNN
FVPGTGLSPDKMLLGRSFAYADAHRARLGVNYKQIPVNAPKCPVHGYTKGGAMRMRDAHDPAYVPNSKGGPAADRQRFPE
NAVWAADGEFVRAAYTLRPDDDDFSQAHALVNRVMDDAARDRLVSNIVGHVLQGVEEPVLSRVFEYWSKIDETIGARVKE
GVLAERAGD
>Mature_488_residues
TTEQTTAYHTTESGIPVSSDEHSLTVGADGPILLHDHYLIEQIAAFNREMIPDRQPHAKGSGAFGRFEVTHDVSRYTCAK
FLQPGARTEVVARFSTVAGEAGSPDTWRDPRGFALKFYTEDGNFDMVGNNTPVFFVRDPLKFQHFIHSQKRRVDNGLRDN
DMQWDFWTLSPETAHQVTWLMGDRGIPASWRHMDGFSSHTYLWVNAAGERFWVKYHFKTDQGIKCLTQEQAGQLAGADAD
YHRRDLYTAIKRGEHPSWTLKMQIMPYEDAKTYRINPFDLTKVWPQGEYPLIEVGKLTLDRNPTDFHSQIEQVAFEPNNF
VPGTGLSPDKMLLGRSFAYADAHRARLGVNYKQIPVNAPKCPVHGYTKGGAMRMRDAHDPAYVPNSKGGPAADRQRFPEN
AVWAADGEFVRAAYTLRPDDDDFSQAHALVNRVMDDAARDRLVSNIVGHVLQGVEEPVLSRVFEYWSKIDETIGARVKEG
VLAERAGD

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=473, Percent_Identity=48.6257928118393, Blast_Score=462, Evalue=1e-130,
Organism=Escherichia coli, GI48994891, Length=384, Percent_Identity=44.7916666666667, Blast_Score=328, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI71998444, Length=476, Percent_Identity=47.2689075630252, Blast_Score=440, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI25147792, Length=480, Percent_Identity=43.75, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI25151141, Length=480, Percent_Identity=43.75, Blast_Score=401, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6320462, Length=487, Percent_Identity=44.1478439425051, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321525, Length=535, Percent_Identity=35.8878504672897, Blast_Score=336, Evalue=6e-93,
Organism=Drosophila melanogaster, GI17981717, Length=474, Percent_Identity=49.789029535865, Blast_Score=462, Evalue=1e-130,
Organism=Drosophila melanogaster, GI19920968, Length=480, Percent_Identity=44.375, Blast_Score=417, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55232; Mature: 55101

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEQTTAYHTTESGIPVSSDEHSLTVGADGPILLHDHYLIEQIAAFNREMIPDRQPHAK
CCCCCCEEEEECCCCCCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCC
GSGAFGRFEVTHDVSRYTCAKFLQPGARTEVVARFSTVAGEAGSPDTWRDPRGFALKFYT
CCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
EDGNFDMVGNNTPVFFVRDPLKFQHFIHSQKRRVDNGLRDNDMQWDFWTLSPETAHQVTW
CCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEE
LMGDRGIPASWRHMDGFSSHTYLWVNAAGERFWVKYHFKTDQGIKCLTQEQAGQLAGADA
EECCCCCCCCCHHCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCHHHHHHCCCCCCCCC
DYHRRDLYTAIKRGEHPSWTLKMQIMPYEDAKTYRINPFDLTKVWPQGEYPLIEVGKLTL
CHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEECCEEEEEECCCCCCCEEEECEEEE
DRNPTDFHSQIEQVAFEPNNFVPGTGLSPDKMLLGRSFAYADAHRARLGVNYKQIPVNAP
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCEEECCCCCC
KCPVHGYTKGGAMRMRDAHDPAYVPNSKGGPAADRQRFPENAVWAADGEFVRAAYTLRPD
CCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCEEEEEEEECCC
DDDFSQAHALVNRVMDDAARDRLVSNIVGHVLQGVEEPVLSRVFEYWSKIDETIGARVKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLAERAGD
CHHHHCCCC
>Mature Secondary Structure 
TTEQTTAYHTTESGIPVSSDEHSLTVGADGPILLHDHYLIEQIAAFNREMIPDRQPHAK
CCCCCEEEEECCCCCCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCC
GSGAFGRFEVTHDVSRYTCAKFLQPGARTEVVARFSTVAGEAGSPDTWRDPRGFALKFYT
CCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
EDGNFDMVGNNTPVFFVRDPLKFQHFIHSQKRRVDNGLRDNDMQWDFWTLSPETAHQVTW
CCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEE
LMGDRGIPASWRHMDGFSSHTYLWVNAAGERFWVKYHFKTDQGIKCLTQEQAGQLAGADA
EECCCCCCCCCHHCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCHHHHHHCCCCCCCCC
DYHRRDLYTAIKRGEHPSWTLKMQIMPYEDAKTYRINPFDLTKVWPQGEYPLIEVGKLTL
CHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEECCEEEEEECCCCCCCEEEECEEEE
DRNPTDFHSQIEQVAFEPNNFVPGTGLSPDKMLLGRSFAYADAHRARLGVNYKQIPVNAP
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCEEECCCCCC
KCPVHGYTKGGAMRMRDAHDPAYVPNSKGGPAADRQRFPENAVWAADGEFVRAAYTLRPD
CCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCEEEEEEEECCC
DDDFSQAHALVNRVMDDAARDRLVSNIVGHVLQGVEEPVLSRVFEYWSKIDETIGARVKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLAERAGD
CHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]