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The map label for this gene is argD [H]

Identifier: 162139850

GI number: 162139850

Start: 570129

End: 571340

Strand: Direct

Name: argD [H]

Synonym: Nwi_0513

Alternate gene names: 162139850

Gene position: 570129-571340 (Clockwise)

Preceding gene: 75674709

Following gene: 75674712

Centisome position: 16.76

GC content: 65.43

Gene sequence:

>1212_bases
ATGACCACAGCCGCGGCGTCTCATCTGTTGCCCGTTTTCGCAAGGGCCGATCTTTCATTCGAGAGCGGTGAAGGAGCCTG
GCTGCTCGGCTCGGACGGCGGACGTTATCTCGATTTCACGAGCGGCGTTGCCGTGAATGCGCTGGGCCATTGCCATCCGC
ATCTCGTCGCCGCGCTTCAGGCGCAGACGGCGAAGCTGTGGCACGTCTCGAACCTGTTCAAGTCGCCCGACGGCGAGCGC
CTGGCGGTGCGGCTCTGCGAGCAGAGTTTCGCCGATTTCGTCTTCTTCGCCAATTCGGGCGCCGAGGCGGTTGAATGCGC
CATCAAGATCGTGCGTCGTTATCATGCCGGCAGGGGTAATCCGGAACGCTATCGGATTGTCACCTTCGAGGGCGCCTTTC
ATGGCCGCACGCTGGCGATGCTGGCCGCTACCGGCTCGAAAAAATACCTCGAAGGATACGGGCCGCCGGCGGACGGTTTT
GACCAGGTGCCGCTCGACGATATCGAAGCCGTAAAGAAGGCGGTCGGCCCCGAGACCGCCGGCATCCTGATCGAGCCGTT
GCAAGGCGAAGGCGGCGTGCGCGAGCCGCCTCCTGCGTTCTTCCGGGCGCTGCGCCAGCTTTGCGACGAGCGCGGTCTGC
TGCTGGTGTTCGACGAGGTGCAGACCGGCATGGGCCGCACCGGCGATCTGTTCGCCTACAGGCGCATCGGCGTCGCGCCG
GACGTGATGTCACTGGCGAAAGCGCTCGGCGGGGGCTTTCCGATCGGCGCCTGTCTTGCGACGGCGGAAGCCGCGTCGGG
CATGACTCCGGGCTCGCACGGTTCGACCTTCGGCGGCAATCCGCTGGCGGTGGCGGCGGCTCATGCCGTGCTCGACGTGA
TGCTCGCTCCCGGCTTCTTCGAGCGGACACGAAAGATGTCGCTGCTGTTGAAACAGAAGCTGGCCTCGCTCGTCGATCGT
TATCCGGATGTGCTGAGCGAGGTGCGCGGCGAGGGGCTTCTGATCGGCCTCAAGGCCGTCGTTCCGTCGGGTGATCTGGT
CAGCGCGTTGCGTGAGGAAAAGCTCCTGACCGTCGGCGCCGGCGAAAACGTCGTTCGCTTGCTGCCGCCGCTGATCATCG
GCGAGGCCGAGATCAACGAGGCGGCGCAGAGGCTGGAGCGGGCTTGCGTCAGGCTGTCGAGCGCATCCGCCAGCAAGGAA
GCCGCGCAATGA

Upstream 100 bases:

>100_bases
TTTCGGGGCTGACAGTTCATCTTTCGGAGCTGACAGTTCATTGATCGCGCCACAGCGCGGTCGGGCCGAACCGCTCCCAC
CATCCAACCGGCAAACCGTC

Downstream 100 bases:

>100_bases
GCAAGGCGCCGCGGCATTTTCTCGACCTGCTCGATATGTCGACCGGGGAGTTGCGCGCGATCCTCGACGCCAGCGTCGCG
ATGAAGAAGCGGCGCAAGGA

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT 1 [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTTAAASHLLPVFARADLSFESGEGAWLLGSDGGRYLDFTSGVAVNALGHCHPHLVAALQAQTAKLWHVSNLFKSPDGER
LAVRLCEQSFADFVFFANSGAEAVECAIKIVRRYHAGRGNPERYRIVTFEGAFHGRTLAMLAATGSKKYLEGYGPPADGF
DQVPLDDIEAVKKAVGPETAGILIEPLQGEGGVREPPPAFFRALRQLCDERGLLLVFDEVQTGMGRTGDLFAYRRIGVAP
DVMSLAKALGGGFPIGACLATAEAASGMTPGSHGSTFGGNPLAVAAAHAVLDVMLAPGFFERTRKMSLLLKQKLASLVDR
YPDVLSEVRGEGLLIGLKAVVPSGDLVSALREEKLLTVGAGENVVRLLPPLIIGEAEINEAAQRLERACVRLSSASASKE
AAQ

Sequences:

>Translated_403_residues
MTTAAASHLLPVFARADLSFESGEGAWLLGSDGGRYLDFTSGVAVNALGHCHPHLVAALQAQTAKLWHVSNLFKSPDGER
LAVRLCEQSFADFVFFANSGAEAVECAIKIVRRYHAGRGNPERYRIVTFEGAFHGRTLAMLAATGSKKYLEGYGPPADGF
DQVPLDDIEAVKKAVGPETAGILIEPLQGEGGVREPPPAFFRALRQLCDERGLLLVFDEVQTGMGRTGDLFAYRRIGVAP
DVMSLAKALGGGFPIGACLATAEAASGMTPGSHGSTFGGNPLAVAAAHAVLDVMLAPGFFERTRKMSLLLKQKLASLVDR
YPDVLSEVRGEGLLIGLKAVVPSGDLVSALREEKLLTVGAGENVVRLLPPLIIGEAEINEAAQRLERACVRLSSASASKE
AAQ
>Mature_402_residues
TTAAASHLLPVFARADLSFESGEGAWLLGSDGGRYLDFTSGVAVNALGHCHPHLVAALQAQTAKLWHVSNLFKSPDGERL
AVRLCEQSFADFVFFANSGAEAVECAIKIVRRYHAGRGNPERYRIVTFEGAFHGRTLAMLAATGSKKYLEGYGPPADGFD
QVPLDDIEAVKKAVGPETAGILIEPLQGEGGVREPPPAFFRALRQLCDERGLLLVFDEVQTGMGRTGDLFAYRRIGVAPD
VMSLAKALGGGFPIGACLATAEAASGMTPGSHGSTFGGNPLAVAAAHAVLDVMLAPGFFERTRKMSLLLKQKLASLVDRY
PDVLSEVRGEGLLIGLKAVVPSGDLVSALREEKLLTVGAGENVVRLLPPLIIGEAEINEAAQRLERACVRLSSASASKEA
AQ

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=398, Percent_Identity=33.9195979899498, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=34.8837209302326, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI13994255, Length=441, Percent_Identity=30.6122448979592, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=24.5939675174014, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI24119277, Length=404, Percent_Identity=26.980198019802, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI226442709, Length=396, Percent_Identity=24.7474747474747, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=23.2018561484919, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI188536080, Length=412, Percent_Identity=25.7281553398058, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI38679950, Length=412, Percent_Identity=25.7281553398058, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI38679946, Length=412, Percent_Identity=25.7281553398058, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1789759, Length=391, Percent_Identity=45.0127877237852, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1788044, Length=395, Percent_Identity=42.2784810126582, Blast_Score=304, Evalue=8e-84,
Organism=Escherichia coli, GI145693181, Length=397, Percent_Identity=36.7758186397985, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1789016, Length=409, Percent_Identity=35.4523227383863, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=36.25, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1786991, Length=400, Percent_Identity=31.75, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=32.3717948717949, Blast_Score=124, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=375, Percent_Identity=33.6, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI32564660, Length=451, Percent_Identity=27.9379157427938, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=262, Percent_Identity=35.4961832061069, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=415, Percent_Identity=26.5060240963855, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=437, Percent_Identity=26.5446224256293, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=28.75, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=386, Percent_Identity=34.9740932642487, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=413, Percent_Identity=33.4140435835351, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6324386, Length=404, Percent_Identity=23.019801980198, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=419, Percent_Identity=25.0596658711217, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21357415, Length=395, Percent_Identity=34.1772151898734, Blast_Score=218, Evalue=8e-57,
Organism=Drosophila melanogaster, GI161085790, Length=440, Percent_Identity=29.3181818181818, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI28574759, Length=429, Percent_Identity=29.6037296037296, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=27.2946859903382, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI281366494, Length=435, Percent_Identity=26.8965517241379, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24667139, Length=435, Percent_Identity=26.8965517241379, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24667143, Length=435, Percent_Identity=26.8965517241379, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42633; Mature: 42502

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAAASHLLPVFARADLSFESGEGAWLLGSDGGRYLDFTSGVAVNALGHCHPHLVAALQ
CCCCHHHHHHHHHHHCCCCEECCCCEEEEECCCCCEEEECCCCHHHHHHCCCHHHHHHHH
AQTAKLWHVSNLFKSPDGERLAVRLCEQSFADFVFFANSGAEAVECAIKIVRRYHAGRGN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCCC
PERYRIVTFEGAFHGRTLAMLAATGSKKYLEGYGPPADGFDQVPLDDIEAVKKAVGPETA
CCEEEEEEEECCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
GILIEPLQGEGGVREPPPAFFRALRQLCDERGLLLVFDEVQTGMGRTGDLFAYRRIGVAP
CEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCCHHHHHCCCCH
DVMSLAKALGGGFPIGACLATAEAASGMTPGSHGSTFGGNPLAVAAAHAVLDVMLAPGFF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
ERTRKMSLLLKQKLASLVDRYPDVLSEVRGEGLLIGLKAVVPSGDLVSALREEKLLTVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCEEEECC
GENVVRLLPPLIIGEAEINEAAQRLERACVRLSSASASKEAAQ
CCCHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure 
TTAAASHLLPVFARADLSFESGEGAWLLGSDGGRYLDFTSGVAVNALGHCHPHLVAALQ
CCCHHHHHHHHHHHCCCCEECCCCEEEEECCCCCEEEECCCCHHHHHHCCCHHHHHHHH
AQTAKLWHVSNLFKSPDGERLAVRLCEQSFADFVFFANSGAEAVECAIKIVRRYHAGRGN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCCC
PERYRIVTFEGAFHGRTLAMLAATGSKKYLEGYGPPADGFDQVPLDDIEAVKKAVGPETA
CCEEEEEEEECCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
GILIEPLQGEGGVREPPPAFFRALRQLCDERGLLLVFDEVQTGMGRTGDLFAYRRIGVAP
CEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCCHHHHHCCCCH
DVMSLAKALGGGFPIGACLATAEAASGMTPGSHGSTFGGNPLAVAAAHAVLDVMLAPGFF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
ERTRKMSLLLKQKLASLVDRYPDVLSEVRGEGLLIGLKAVVPSGDLVSALREEKLLTVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCEEEECC
GENVVRLLPPLIIGEAEINEAAQRLERACVRLSSASASKEAAQ
CCCHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]