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The map label for this gene is aroC

Identifier: 162139849

GI number: 162139849

Start: 707876

End: 708982

Strand: Direct

Name: aroC

Synonym: Nwi_0629

Alternate gene names: 162139849

Gene position: 707876-708982 (Clockwise)

Preceding gene: 75674826

Following gene: 75674836

Centisome position: 20.81

GC content: 65.22

Gene sequence:

>1107_bases
ATGTCCCACAATACCTTCGGTCACCTGTTCCGTGTCACGACCTTTGGCGAGAGCCACGGGGTCGCGATCGGCTGCGTGGT
CGATGGTTGTCCCCCGATGCTGCCGCTCACGGCCGAGGAAATCCAGCGCGATCTCGATCGCCGCCGTCCCGGCCAATCGC
GGTTCACCACGCAGCGGCAGGAGCCGGATGCGGTGAAGATCCTGTCCGGGGTCATGCCGCACCCCGGCACAGGCGAGCAG
GTGACAACGGGTGCGCCGATCGGGCTTCTGATCGAGAATACCGATCAGCGATCGAAGGACTACTCCGACATCAAGGACAA
GTTTCGCCCCGGTCATGCCGACTTCACCTATGAGGCGAAATACGGCATCCGAGACTATCGCGGGGGCGGGCGCTCCTCGG
CGCGCGAGACCGCGATGCGGGTCGCCGCCGGCGCCATCGCGCGCAAGGTTGTCTCCGGCATGAGGGTGCGTGGCGCTCTG
GTTCAGATGGGGCCGCACAAGATCGATCGGGACAAATGGGATTGGGACGAGATCGCGAGGAATCCGTTCTTCTGTCCCGA
CAAGGACAAGGCTGCGTTCTTCGAGAGCTATCTTGACGGCATCCGCAAAAGCGGCTCCTCGATCGGCGCCGTGATCGAGG
TGGTGGCCGATGGGGTGCCCGCAGGACTTGGCGCGCCGATCTATGCCAAGCTCGACGGCGACCTGGCCGCGGCGCTGATG
AGCATCAATGCGGTCAAGGGCGTGGAGATCGGCGCCGGCTTCGGAGCCGCCGCGTTGACCGGGGAGGAGAACGCCGACGA
GATGCGCAGTTCTTCGTCCGATATGGGCAACCACGGCCCGGTGTTCACCTCCAACCATGCCGGCGGCATTCTCGGCGGCA
TATCCACCGGTCAGCCCATCGTGGCGCGGTTCGCGGTGAAGCCGACGTCGTCGATCCTGTCGCCGCGCAAGACCGTCGAT
CGCAACGGAGCCGAAACAGACATCTTCACCAGGGGCCGTCACGATCCCTGCGTCGGCATCCGGGCGGTGCCGGTGGGAGA
GGCCATGGTTGCCTGCGTTCTGGCGGATCATGTCCTGCGACATCGAGGGCAGGTCGGCGCGAGTTAG

Upstream 100 bases:

>100_bases
CTTCCGGGGAGGATAGCGGCAAGCTCGACGCCAGCGCGAATGTTGCGATTCTCGCAACATGCCGCTACGAGAAGTAGCGA
TTTCGCGCTTCGGATTGTTG

Downstream 100 bases:

>100_bases
AGCCTTTCCGCTTCTGATGGAATCAGAAGCGGGGCTCTATGATTTTGTTTTGACGCGTTTTCTTCACGCGAACCGGTGTC
CACTTCGCTCGAAAAACGCT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSHNTFGHLFRVTTFGESHGVAIGCVVDGCPPMLPLTAEEIQRDLDRRRPGQSRFTTQRQEPDAVKILSGVMPHPGTGEQ
VTTGAPIGLLIENTDQRSKDYSDIKDKFRPGHADFTYEAKYGIRDYRGGGRSSARETAMRVAAGAIARKVVSGMRVRGAL
VQMGPHKIDRDKWDWDEIARNPFFCPDKDKAAFFESYLDGIRKSGSSIGAVIEVVADGVPAGLGAPIYAKLDGDLAAALM
SINAVKGVEIGAGFGAAALTGEENADEMRSSSSDMGNHGPVFTSNHAGGILGGISTGQPIVARFAVKPTSSILSPRKTVD
RNGAETDIFTRGRHDPCVGIRAVPVGEAMVACVLADHVLRHRGQVGAS

Sequences:

>Translated_368_residues
MSHNTFGHLFRVTTFGESHGVAIGCVVDGCPPMLPLTAEEIQRDLDRRRPGQSRFTTQRQEPDAVKILSGVMPHPGTGEQ
VTTGAPIGLLIENTDQRSKDYSDIKDKFRPGHADFTYEAKYGIRDYRGGGRSSARETAMRVAAGAIARKVVSGMRVRGAL
VQMGPHKIDRDKWDWDEIARNPFFCPDKDKAAFFESYLDGIRKSGSSIGAVIEVVADGVPAGLGAPIYAKLDGDLAAALM
SINAVKGVEIGAGFGAAALTGEENADEMRSSSSDMGNHGPVFTSNHAGGILGGISTGQPIVARFAVKPTSSILSPRKTVD
RNGAETDIFTRGRHDPCVGIRAVPVGEAMVACVLADHVLRHRGQVGAS
>Mature_367_residues
SHNTFGHLFRVTTFGESHGVAIGCVVDGCPPMLPLTAEEIQRDLDRRRPGQSRFTTQRQEPDAVKILSGVMPHPGTGEQV
TTGAPIGLLIENTDQRSKDYSDIKDKFRPGHADFTYEAKYGIRDYRGGGRSSARETAMRVAAGAIARKVVSGMRVRGALV
QMGPHKIDRDKWDWDEIARNPFFCPDKDKAAFFESYLDGIRKSGSSIGAVIEVVADGVPAGLGAPIYAKLDGDLAAALMS
INAVKGVEIGAGFGAAALTGEENADEMRSSSSDMGNHGPVFTSNHAGGILGGISTGQPIVARFAVKPTSSILSPRKTVDR
NGAETDIFTRGRHDPCVGIRAVPVGEAMVACVLADHVLRHRGQVGAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=367, Percent_Identity=62.9427792915531, Blast_Score=438, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=42.7055702917772, Blast_Score=273, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_NITWN (Q3SUZ5)

Other databases:

- EMBL:   CP000115
- RefSeq:   YP_317248.2
- HSSP:   P63611
- ProteinModelPortal:   Q3SUZ5
- SMR:   Q3SUZ5
- STRING:   Q3SUZ5
- GeneID:   3676242
- GenomeReviews:   CP000115_GR
- KEGG:   nwi:Nwi_0629
- NMPDR:   fig|323098.3.peg.300
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- PhylomeDB:   Q3SUZ5
- ProtClustDB:   PRK05382
- BioCyc:   NWIN323098:NWI_0629-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39166; Mature: 39035

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTFGESHGVAIGCVVDGCPPMLPLTAEEIQRDLDRRRPGQSRFTTQRQ
CCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDAVKILSGVMPHPGTGEQVTTGAPIGLLIENTDQRSKDYSDIKDKFRPGHADFTYEAK
CCHHHHHHHCCCCCCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEC
YGIRDYRGGGRSSARETAMRVAAGAIARKVVSGMRVRGALVQMGPHKIDRDKWDWDEIAR
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHC
NPFFCPDKDKAAFFESYLDGIRKSGSSIGAVIEVVADGVPAGLGAPIYAKLDGDLAAALM
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHH
SINAVKGVEIGAGFGAAALTGEENADEMRSSSSDMGNHGPVFTSNHAGGILGGISTGQPI
HHHHHCCEEECCCCCCEEECCCCCHHHHHHCCCCCCCCCCEEECCCCCCEEECCCCCCCE
VARFAVKPTSSILSPRKTVDRNGAETDIFTRGRHDPCVGIRAVPVGEAMVACVLADHVLR
EEEEECCCHHHHHCCHHHHCCCCCCCCCEECCCCCCCCCEEECCCHHHHHHHHHHHHHHH
HRGQVGAS
HCCCCCCC
>Mature Secondary Structure 
SHNTFGHLFRVTTFGESHGVAIGCVVDGCPPMLPLTAEEIQRDLDRRRPGQSRFTTQRQ
CCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDAVKILSGVMPHPGTGEQVTTGAPIGLLIENTDQRSKDYSDIKDKFRPGHADFTYEAK
CCHHHHHHHCCCCCCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEC
YGIRDYRGGGRSSARETAMRVAAGAIARKVVSGMRVRGALVQMGPHKIDRDKWDWDEIAR
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHC
NPFFCPDKDKAAFFESYLDGIRKSGSSIGAVIEVVADGVPAGLGAPIYAKLDGDLAAALM
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHH
SINAVKGVEIGAGFGAAALTGEENADEMRSSSSDMGNHGPVFTSNHAGGILGGISTGQPI
HHHHHCCEEECCCCCCEEECCCCCHHHHHHCCCCCCCCCCEEECCCCCCEEECCCCCCCE
VARFAVKPTSSILSPRKTVDRNGAETDIFTRGRHDPCVGIRAVPVGEAMVACVLADHVLR
EEEEECCCHHHHHCCHHHHCCCCCCCCCEECCCCCCCCCEEECCCHHHHHHHHHHHHHHH
HRGQVGAS
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA