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The map label for this gene is tsf [H]

Identifier: 162139171

GI number: 162139171

Start: 1836774

End: 1837814

Strand: Direct

Name: tsf [H]

Synonym: MGAS10750_Spy1873

Alternate gene names: 162139171

Gene position: 1836774-1837814 (Clockwise)

Preceding gene: 94995268

Following gene: 94995273

Centisome position: 94.82

GC content: 42.46

Gene sequence:

>1041_bases
ATGGCAGAAATTACAGCTAAGCTTGTAAAAGAATTACGTGAAAAATCTGGTGCTGGCGTTATGGACGCTAAAAAAGCACT
TGTTGAAACAGATGGTGACATGGACAAAGCCGTTGAACTTCTTCGTGAAAAAGGAATGGCTAAAGCGGCTAAAAAAGCTG
ACCGTGTTGCCGCTGAAGGTTTAACAGGCGTTTACGTTCATGGTAACGTTGCTGCTGTTGTTGAAGTTAACGCTGAAACA
GACTTTGTTGCTAAAAATGCTCAATTCGTTGAATTGGTAAACGCAACTGCTAAAGTTATCGCTGAAGGCAAACCAGCTAA
CAACGATGAAGCACTTGCACTTGTTATGCCTTCAGGTGAAACTCTTGCTGAAGCTTACGTTAATGCAACTGCTACCATCG
GAGAAAAAATCTCATTCCGTCGTTTTGCTTTGATTGAAAAAACAGATGAGCAACACTTCGGTGCTTACCAACATAATGGT
GGCCGTATCGGGGTTATCTCAGTTGTCGAAGGCGGCGACGATGCTCTTGCTAAACAAGTATCAATGCATATCGCTGCAAT
GAAACCAACTGTTCTTTCATACACTGAGCTTGATGCACAATTCATCAAAGATGAACTTGCTCAATTGAACCACGCTATCG
AACTTGACAACGAATCGCGTGCAATGGTTGACAAACCAGCACTTCCATTCTTGAAATACGGTTCAAAAGCTCAATTATCA
GACGACGTGATTACTGCTGCTGAAGCAGACATCAAAGCTGAACTTGCTGCTGAAGGCAAACCAGAAAAGATCTGGGACAA
AATCATCCCAGGTAAAATGGACCGCTTCATGCTTGACAACACTAAAGTTGACCAAGCTTACACTCTTCTTGCACAAGTTT
ACATCATGGACGACAGCAAAACTGTTGAAGCCTACCTTGACTCAGTAAACGCTAAAGCGATTGCTTTTGCACGTTTTGAA
GTTGGTGAAGGTATCGAGAAAAAAGCTAACGACTTTGAATCAGAAGTTGCAGCTACTATGGCTGCTGCCCTTAACAACTA
A

Upstream 100 bases:

>100_bases
TCGTTTGTCTTTAACAATCGAAAACCAAACGGGGCAGAAAGCAAACCGCTCTGTCTCGTTTTTTGAAACCAAAACAAATA
TCATTTGGAGGATACTACAC

Downstream 100 bases:

>100_bases
TCACTTATTTCTGATAAGTCTAAAAAAGGCAACCTTCTTTCCTGAGGGTTGTCTTTTTGTTGTGTCAAAACGGACACCAA
TAAGGAAGAAAAAAACTGAT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAET
DFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLS
DDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFE
VGEGIEKKANDFESEVAATMAAALNN

Sequences:

>Translated_346_residues
MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAET
DFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLS
DDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFE
VGEGIEKKANDFESEVAATMAAALNN
>Mature_345_residues
AEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETD
FVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNGG
RIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLSD
DVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEV
GEGIEKKANDFESEVAATMAAALNN

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=230, Percent_Identity=28.2608695652174, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI291084498, Length=94, Percent_Identity=42.5531914893617, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI291084502, Length=97, Percent_Identity=41.2371134020619, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI291084500, Length=97, Percent_Identity=41.2371134020619, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786366, Length=338, Percent_Identity=36.6863905325444, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17561440, Length=228, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19921466, Length=212, Percent_Identity=30.6603773584906, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 37258; Mature: 37126

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEG
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCC
LTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGE
CCEEEEECCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCH
TLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNGGRIGVISVVEGGDDALAKQV
HHHHHHHHHHHHHCCCCCHHHEEEEECCCHHHCCCEECCCCEEEEEEEEECCCHHHHHHH
SMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLS
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCCHHCCCCCCHHHHCCCCCCCC
DDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSK
CHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCCHHHEECCCCHHHHHHHHEEEEEECCCH
TVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN
HHHHHHHCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEG
CCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCC
LTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGE
CCEEEEECCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCH
TLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNGGRIGVISVVEGGDDALAKQV
HHHHHHHHHHHHHCCCCCHHHEEEEECCCHHHCCCEECCCCEEEEEEEEECCCHHHHHHH
SMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLS
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCCHHCCCCCCHHHHCCCCCCCC
DDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSK
CHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCCHHHEECCCCHHHHHHHHEEEEEECCCH
TVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN
HHHHHHHCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]