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The map label for this gene is ynfJ [H]

Identifier: 162138437

GI number: 162138437

Start: 1705820

End: 1707001

Strand: Direct

Name: ynfJ [H]

Synonym: UTI89_C1779

Alternate gene names: 162138437

Gene position: 1705820-1707001 (Clockwise)

Preceding gene: 162138438

Following gene: 91210806

Centisome position: 33.67

GC content: 54.23

Gene sequence:

>1182_bases
ATGTTCCGCCGTCTGCTTATCGCAACAATCGTCGGTATTCTTGCGGCCTTTGCCGTTGCCGGGTTTCGTCATGCGATGCT
GCTACTGGAGTGGCTGTTCCTCAATAATGACTCCGGCAGTCTGGTCAATGCAGCGACAAATCTTTCCCCGTGGCGACGGC
TGCTAACCCCGGCGCTCGGCGGACTGGCGGCGGGTTTGTTGCTGATGGGCTGGCAGAAATTTACCCAGCAACGCCCTCAT
GCGCCGACCGATTACATGGAAGCGTTGCAAACCGATGGTCAGTTTGATTACGCAGCAAGCCTGGTTAAATCGCTTGCCTC
TCTACTGGTAGTAACCAGCGGCAGTGCAATTGGTCGCGAAGGTGCGATGATTCTTTTAGCTGCCCTTGCAGCCTCGTGTT
TTGCCCAACGTCTTACGCCACGCCAGGAGTGGAAATTATGGATCGCCTGTGGAGCTGCGGCGGGAATGGCTGCGGCCTAT
CGCGCCCCGCTTGCTGGCAGTTTATTTATAGCCGAAGTGCTGTTTGGCACTATGATGTTGGCCTCTCTCGGCCCGGTGAT
TATTTCCGCCGTCGTGGCGTTGCTGGTTAGCAATCTTATTAATCATAGCGACGCATTACTCTACAGCGGACCACTGTTGT
TAACGTTAATGAACGCCTGTCATCGTGGATTTGTGAGTCTCAAGCTTGCGCCGCCCTGGCAACTGGCACTGGGCGGGTTG
ATCGTGGGTCTGCTTTCCCTGTTCACACCTGCAGTGTGGGGCAACGGCTATAGCACCGTACAATCCTTTTTAACCGCTCC
GCCACTGTTAATGATCATTGCCGGGATCTTCCTCTGTAAACTGTGTGCCGTGCTGGCGAGTAGTGGTTCTGGCGCGCCCG
GTGGTGTCTTTACACCGACGCTATTTATCGGTCTTGCCATTGGCATGTTGTATGGTCGTAGCCTGGGATTATGGTTACCT
GATGGCGAAGAAATTACGCTTTTACTCGGATTGACAGGGATGGCGACACTGTTGGCGGCGACCACGCACGCGCCGATTAT
GTCGACGTTGATGATATGTGAAATGACCGGGGAGTATCAGCTACTCCCCGGTTTATTGATTGCCTGCGTAATTGCGTCGG
TAATTTCGCGGACGTTACACCGTGACTCTATCTACCGCCAGCACACTGCGAAGCATAGCTAA

Upstream 100 bases:

>100_bases
GCTTTTGCGGCTGGCCTCTTTTGCCGCAAAATAGTCGCCCGTGTTTCATTGCCCATTTCTGCTCATGCATCATCTACACA
TCTATCCGGATCTGCGCACT

Downstream 100 bases:

>100_bases
GCGGATGTATTGCCCCAGTTCACGCTGTTCGGCGCGCGGCAGATAAGGCAGTTCACCAATGAGCGGTGCCGGAAGTTTTT
TACCGAGCACATCAATGATT

Product: putative voltage-gated ClC-type chloride channel ClcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MFRRLLIATIVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPH
APTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRLTPRQEWKLWIACGAAAGMAAAY
RAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDALLYSGPLLLTLMNACHRGFVSLKLAPPWQLALGGL
IVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWLP
DGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAKHS

Sequences:

>Translated_393_residues
MFRRLLIATIVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPH
APTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRLTPRQEWKLWIACGAAAGMAAAY
RAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDALLYSGPLLLTLMNACHRGFVSLKLAPPWQLALGGL
IVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWLP
DGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAKHS
>Mature_393_residues
MFRRLLIATIVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPH
APTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRLTPRQEWKLWIACGAAAGMAAAY
RAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDALLYSGPLLLTLMNACHRGFVSLKLAPPWQLALGGL
IVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWLP
DGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAKHS

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081943, Length=418, Percent_Identity=92.5837320574163, Blast_Score=690, Evalue=0.0,
Organism=Escherichia coli, GI1786350, Length=263, Percent_Identity=26.2357414448669, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 41519; Mature: 41519

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRRLLIATIVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHH
GLAAGLLLMGWQKFTQQRPHAPTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGRE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GAMILLAALAASCFAQRLTPRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMML
HHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ASLGPVIISAVVALLVSNLINHSDALLYSGPLLLTLMNACHRGFVSLKLAPPWQLALGGL
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
IVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPT
HHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LFIGLAIGMLYGRSLGLWLPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQ
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LLPGLLIACVIASVISRTLHRDSIYRQHTAKHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFRRLLIATIVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHH
GLAAGLLLMGWQKFTQQRPHAPTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGRE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GAMILLAALAASCFAQRLTPRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMML
HHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ASLGPVIISAVVALLVSNLINHSDALLYSGPLLLTLMNACHRGFVSLKLAPPWQLALGGL
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
IVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPT
HHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LFIGLAIGMLYGRSLGLWLPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQ
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LLPGLLIACVIASVISRTLHRDSIYRQHTAKHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA