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The map label for this gene is gcp [H]

Identifier: 161986605

GI number: 161986605

Start: 1191316

End: 1192287

Strand: Reverse

Name: gcp [H]

Synonym: TTHA1252

Alternate gene names: 161986605

Gene position: 1192287-1191316 (Counterclockwise)

Preceding gene: 55981225

Following gene: 55981220

Centisome position: 64.46

GC content: 70.78

Gene sequence:

>972_bases
GTGTGGGTCTTGGGGATTGACACCTCCTGCGACGACACCGGGGTGGGCCTCGTGCGGGACGGAAAGGTGGTGGTGAACCT
GGTGGCGAGCCAGGTGCGCCTGCACGAGGCCTTTGGCGGCGTGGTGCCGGAGCTCGCAAGCCGCGAGCACTTAAAGGCCC
TCCCCCTCCTCGTGGAGAGGGCCCTGGCCGAGGCGGGCCTTAGGCCTAAGGACTTAGACCTCGTGGCCGCCACCCGGGGC
CCCGGGCTCATCGGGGCCCTCCTCGTGGGGTACACCTTCGCCAAGGGGATGGCCTTCGCCCTGGACCGGCCCTTCTACGC
CGTCCACCACCTGGAGGGCCACATCGCGGCCGCCTGGCCTGAAGGGCTACCCCCCCCCTTCCTCGCCCTGGTGGCCTCGG
GGGGGCACACCCACCTCTACGAGGTCTTAGACCTCGGCCGCTACCGCCTCCTCGGGGCCACCCGGGACGACGCCGCCGGG
GAGGCCTTTGACAAGGTGGCGAGGCTTTTGGGCCTCGGCTTTCCCGGGGGGCCCGAGGTGGAGCGCCTGGCCGAGGAGGC
GGAGGAAGCCATTCCCTTCCCCGTGCCCTTAAGGGGACAGGAGGGGTACGACTTCAGCTTCTCCGGGCTCAAGACCAAGG
CCCTCCACCTGGTGGAGAAGGGCCTTCCCAAGGCCGCCCTCGCCAAGGGCTTTCAGGAGGCGGCCATCGCTCACCTCGCC
GAGGTGGTCCTGAAGGCGGCGAAGGACACGGGCCACCGGGTCCTCCTCGTGGCCGGGGGGGTGGCGGCGAACCGGGCGCT
CCAGGAGCGCTTCAAGGAGGCGGGCCTGGAGGTGCATTTTCCTCCCCGGGGCCTTTCCCAGGACAACGGGGCCATGATCG
CCCTCGCCGCCTGGCGCCGCCACCAAAGGGGCTTCCCCCCAAGCCCCCTCTCCTTGGGGGCCACGGCCTACTGGCCCTTG
GAGGAGGCCTGA

Upstream 100 bases:

>100_bases
CTAGGGGCCCGCCTCCGGTAGAGGAGGTAGACCAGAAGGAGGACGGGAAGGAGGAGCCAGAGCACCCTGCCCTAAGGCTA
CCCCTGCTAGAGTGAGGGCG

Downstream 100 bases:

>100_bases
GGCTCTTTCTCCCCGTTTTCCCCCTGAAGGGTCCGAGATTGGGGCACGAGGTCCCTTTACCGGGGCCCCATGCTGGCGCA
AGCCAGCATGGGGTGGTATA

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MWVLGIDTSCDDTGVGLVRDGKVVVNLVASQVRLHEAFGGVVPELASREHLKALPLLVERALAEAGLRPKDLDLVAATRG
PGLIGALLVGYTFAKGMAFALDRPFYAVHHLEGHIAAAWPEGLPPPFLALVASGGHTHLYEVLDLGRYRLLGATRDDAAG
EAFDKVARLLGLGFPGGPEVERLAEEAEEAIPFPVPLRGQEGYDFSFSGLKTKALHLVEKGLPKAALAKGFQEAAIAHLA
EVVLKAAKDTGHRVLLVAGGVAANRALQERFKEAGLEVHFPPRGLSQDNGAMIALAAWRRHQRGFPPSPLSLGATAYWPL
EEA

Sequences:

>Translated_323_residues
MWVLGIDTSCDDTGVGLVRDGKVVVNLVASQVRLHEAFGGVVPELASREHLKALPLLVERALAEAGLRPKDLDLVAATRG
PGLIGALLVGYTFAKGMAFALDRPFYAVHHLEGHIAAAWPEGLPPPFLALVASGGHTHLYEVLDLGRYRLLGATRDDAAG
EAFDKVARLLGLGFPGGPEVERLAEEAEEAIPFPVPLRGQEGYDFSFSGLKTKALHLVEKGLPKAALAKGFQEAAIAHLA
EVVLKAAKDTGHRVLLVAGGVAANRALQERFKEAGLEVHFPPRGLSQDNGAMIALAAWRRHQRGFPPSPLSLGATAYWPL
EEA
>Mature_323_residues
MWVLGIDTSCDDTGVGLVRDGKVVVNLVASQVRLHEAFGGVVPELASREHLKALPLLVERALAEAGLRPKDLDLVAATRG
PGLIGALLVGYTFAKGMAFALDRPFYAVHHLEGHIAAAWPEGLPPPFLALVASGGHTHLYEVLDLGRYRLLGATRDDAAG
EAFDKVARLLGLGFPGGPEVERLAEEAEEAIPFPVPLRGQEGYDFSFSGLKTKALHLVEKGLPKAALAKGFQEAAIAHLA
EVVLKAAKDTGHRVLLVAGGVAANRALQERFKEAGLEVHFPPRGLSQDNGAMIALAAWRRHQRGFPPSPLSLGATAYWPL
EEA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=342, Percent_Identity=32.7485380116959, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI8923380, Length=333, Percent_Identity=31.2312312312312, Blast_Score=133, Evalue=3e-31,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=46.1077844311377, Blast_Score=263, Evalue=9e-72,
Organism=Caenorhabditis elegans, GI71995670, Length=317, Percent_Identity=32.1766561514196, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17557464, Length=288, Percent_Identity=31.5972222222222, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320099, Length=366, Percent_Identity=30.8743169398907, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322891, Length=296, Percent_Identity=28.7162162162162, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20129063, Length=332, Percent_Identity=35.2409638554217, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21357207, Length=316, Percent_Identity=31.9620253164557, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 34401; Mature: 34401

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWVLGIDTSCDDTGVGLVRDGKVVVNLVASQVRLHEAFGGVVPELASREHLKALPLLVER
CEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALAEAGLRPKDLDLVAATRGPGLIGALLVGYTFAKGMAFALDRPFYAVHHLEGHIAAAWP
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEHHCCCCEEEECC
EGLPPPFLALVASGGHTHLYEVLDLGRYRLLGATRDDAAGEAFDKVARLLGLGFPGGPEV
CCCCCHHHHHEECCCCHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHH
ERLAEEAEEAIPFPVPLRGQEGYDFSFSGLKTKALHLVEKGLPKAALAKGFQEAAIAHLA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EVVLKAAKDTGHRVLLVAGGVAANRALQERFKEAGLEVHFPPRGLSQDNGAMIALAAWRR
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEHHHH
HQRGFPPSPLSLGATAYWPLEEA
HHCCCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure
MWVLGIDTSCDDTGVGLVRDGKVVVNLVASQVRLHEAFGGVVPELASREHLKALPLLVER
CEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALAEAGLRPKDLDLVAATRGPGLIGALLVGYTFAKGMAFALDRPFYAVHHLEGHIAAAWP
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEHHCCCCEEEECC
EGLPPPFLALVASGGHTHLYEVLDLGRYRLLGATRDDAAGEAFDKVARLLGLGFPGGPEV
CCCCCHHHHHEECCCCHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHH
ERLAEEAEEAIPFPVPLRGQEGYDFSFSGLKTKALHLVEKGLPKAALAKGFQEAAIAHLA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EVVLKAAKDTGHRVLLVAGGVAANRALQERFKEAGLEVHFPPRGLSQDNGAMIALAAWRR
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEHHHH
HQRGFPPSPLSLGATAYWPLEEA
HHCCCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA