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The map label for this gene is arnB

Identifier: 161984905

GI number: 161984905

Start: 2278098

End: 2279237

Strand: Direct

Name: arnB

Synonym: SBO_2290

Alternate gene names: 161984905

Gene position: 2278098-2279237 (Clockwise)

Preceding gene: 82544729

Following gene: 82544736

Centisome position: 50.4

GC content: 51.67

Gene sequence:

>1140_bases
ATGTCAGAATTTTTGCCTTTTTCGCGACCAGCAATGGGCGTGGAGGAACTCGCTGCAGTTAAAGAAGTTCTCGAATCCGG
TTGGATCACAACCGGTCCGAAGAATCAGGCGCTTGAGCAAGCCTTTTGCCAGTTGACGGGAAATCAGCATGCCATCGCGG
TCAGTTCAGCCACCGCCGGAATGCATATCACGCTAATGGCGTTGGAAATTGGCAAGGGCGATGAAGTGATTACGCCTTCC
CTGACCTGGGTTTCAACCCTCAATATGATTTCCTTGTTGGGTGCAACGCCGGTAATGGTGGATGTCGACCGCGATACGCT
GATGGTCACGCCTGAAGCGATCGAGTCAGCCATTACGCCACGCACTAAAGCCATCATTCCGGTGCATTATGCCGGTGCGC
CAGCAGATATTGACGCCATTCGCGCCATTGGCGAACGTTACGGCATCGCAGTTATCGAAGATGCTGCCCATGCCGTCGGT
ACGTATTACAAAGGGCGACATATTGGCGCAAAAGGTACCGCTATTTTTTCATTTCATGCCATTAAAAATATTACCTGTGC
GGAAGGTGGCCTGATTGTAACTGATAATGAAAACCTTGCCCGCCAGCTACGGATGCTGAAATTTCACGGCCTGGGTGTCG
ATGCCTATGACAGACAAACCTGGGGCCGAGCACCGCAGGCTGAAGTCTTAACACCGGGCTATAAGTACAATCTGACCGAT
ATTAACGCCGCAATTGCCCTGACACAGTTAGCAAAATTAGAGCACCTCAACACCCGTCGGCGCGAAATTGCCCAGCAATA
TCAGCAAGCACTGGCTGCTCTCCCCTTTCAGCCATTAAGCCTTCCCGCCTGGCCGCACGTTCACGCCTGGCATCTGTTTA
TTATTCGTGTCGATGAACAACGTTGTGGTATCAGTCGCGATGCGTTGATGGAAGCGTTAAAAGAAAGAGGCATTGGTACC
GGGTTACATTTCCGCGCCGCTCACACACAAAAATATTATCGCGAGCGTTTTCCCACGCTGTCGTTACCGAATACCGAATG
GAATAGCGAACGCATCTGTTCTTTGCCGCTGTTCCCGGATATGACTACCGCCGATGCCGACCGTGTCATCACAGCCCTTC
AGCAACTCGCAGGACAATAA

Upstream 100 bases:

>100_bases
ATATTCTATCCTTAAAATTTCGTTCCAAATGGCAAAATATACACAACACTCTTTATAGCAAATATAAGTGGACAGGTATT
CAATGGCGGAAGGAAAAGCA

Downstream 100 bases:

>100_bases
GCCATGTTTGAAATCCACCCTGTTAAGAAAGTCTCGGTGGTTATTCCCGTTTATAACGAGCAGGAAAGCTTACCGGAATT
AATCAGGCGCACCACCACAG

Product: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

Products: NA

Alternate protein names: UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-Ara4O aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPS
LTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTD
INAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGT
GLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ

Sequences:

>Translated_379_residues
MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPS
LTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTD
INAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGT
GLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
>Mature_378_residues
SEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSL
TWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGT
YYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTDI
NAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTG
LHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ

Specific function: Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. ArnB subfamily

Homologues:

Organism=Escherichia coli, GI145693159, Length=379, Percent_Identity=99.2084432717678, Blast_Score=779, Evalue=0.0,
Organism=Escherichia coli, GI2367285, Length=387, Percent_Identity=32.0413436692506, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNB_ECO24 (A7ZP71)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001463600.1
- ProteinModelPortal:   A7ZP71
- SMR:   A7ZP71
- STRING:   A7ZP71
- EnsemblBacteria:   EBESCT00000022966
- GeneID:   5588184
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_2548
- eggNOG:   COG0399
- GeneTree:   EBGT00050000010722
- HOGENOM:   HBG660897
- OMA:   SEWNSAR
- ProtClustDB:   PRK11658
- BioCyc:   ECOL331111:ECE24377A_2548-MONOMER
- HAMAP:   MF_01167
- InterPro:   IPR022850
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000390

Pfam domain/function: PF01041 DegT_DnrJ_EryC1; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.87

Molecular weight: Translated: 41642; Mature: 41511

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
MHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITP
EEEEEEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCEEEECCCCEEEECHHHHHHHCCC
RTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHA
CCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCCEEEEEHH
IKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTD
HCCCEECCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCEECCCCEEECCH
INAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECHH
RCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPD
HCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCC
MTTADADRVITALQQLAGQ
CCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
MHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITP
EEEEEEEEEECCCCCEECCCHHHHHHHHHHHHHCCCCEEEECCCCEEEECHHHHHHHCCC
RTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHA
CCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCCEEEEEHH
IKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTD
HCCCEECCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCEECCCCEEECCH
INAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECHH
RCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPD
HCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCC
MTTADADRVITALQQLAGQ
CCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA