Click here to switch to the map view.

The map label for this gene is gapA2 [H]

Identifier: 161871023

GI number: 161871023

Start: 2149258

End: 2150262

Strand: Reverse

Name: gapA2 [H]

Synonym: NMCC_2119

Alternate gene names: 161871023

Gene position: 2150262-2149258 (Counterclockwise)

Preceding gene: NA

Following gene: 161871022

Centisome position: 99.85

GC content: 55.22

Gene sequence:

>1005_bases
ATGAGCATTAAAGTAGCGATTAACGGTTTCGGCCGCATCGGCCGCCTCGCATTGCGTCAAATTGAAAAAGCCCACGACAT
CGAAGTCGTCGCCGTCAACGACCTGACCCCTGCCGAAATGCTGCTGCACCTTTTCAAATACGACAGCACGCAAGGCCGTT
TCCAAGGTACTGCCGAATTAAAAGACGATGCCATCGTGGTAAACGGCAAAGAAATCAAAGTTTTTGCCAATCCGAATCCC
GAAGAATTGCCTTGGGGCGAGTTGGGTGTGGATGTCGTCCTCGAATGTACCGGCTTCTTTACCAATAAAACCAAAGCCGA
AGCACACATCAGGGCCGGCGCGCGCAAAGTCGTGATTTCCGCACCCGGCGGCAATGATGTGAAAACCGTCGTATATGGCG
TAAACCAAGACATTTTGGACGGCAGCGAAACCGTTATCTCCGCTGCTTCCTGCACCACCAACTGCCTTGCCCCGATGGCG
GCAGTCCTGCAAAAGGAATTCGGCGTAGTCGAAGGCCTGATGACCACCATCCACGCCTACACCGGCGACCAAAACACCCT
TGACGCGCCGCACCGCAAAGGCGATTTGCGCCGCGCCCGCGCCGCCGCGCTCAACATCGTGCCCAACAGCACCGGTGCCG
CCAAGGCCATCGGTCTGGTTATCCCTGAATTGAACGGCAAACTCGACGGCTCCGCCCAACGCGTCCCTGTTGCCACCGGC
TCGCTGACCGAATTGGTTTCCGTCCTCGAACGCCCTGTAACCAAAGAAGAAATCAACGCCGCGATGAAAGCCGCCGCCAG
CGAATCTTACGGCTACAACGAAGATCAAATTGTTTCTTCCGACGTTGTCGGCATCGAATACGGTTCGCTCTTCGATGCGA
CCCAAACCCGCGTGATGACCGTGGGCGGCAAACAATTGGTGAAAACTGTTGCCTGGTACGACAACGAAATGTCCTACACC
TGCCAACTCGTCCGCACTTTGGAATACTTTGCAGGCAAAATCTAA

Upstream 100 bases:

>100_bases
TCAAATAAGCGTCAAGTAGTTAGATGTAATAGTGGAATGTAACTTTATTTCAGAATACAATGCAGGCATCGGACTTTATT
TCACAACCTGGAGACAAAAT

Downstream 100 bases:

>100_bases
GGCTTGAACAAACCTGTGGATAAGTAAATGCCGTCTGAACACATTGCGTTCAGACGGCATTGTTTATCTGTATAGTGGAT
TAAATTTAAACCAGTACGGC

Product: glyceraldehyde 3-phosphate dehydrogenase C

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSIKVAINGFGRIGRLALRQIEKAHDIEVVAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDDAIVVNGKEIKVFANPNP
EELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVISAPGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMA
AVLQKEFGVVEGLMTTIHAYTGDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPVATG
SLTELVSVLERPVTKEEINAAMKAAASESYGYNEDQIVSSDVVGIEYGSLFDATQTRVMTVGGKQLVKTVAWYDNEMSYT
CQLVRTLEYFAGKI

Sequences:

>Translated_334_residues
MSIKVAINGFGRIGRLALRQIEKAHDIEVVAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDDAIVVNGKEIKVFANPNP
EELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVISAPGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMA
AVLQKEFGVVEGLMTTIHAYTGDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPVATG
SLTELVSVLERPVTKEEINAAMKAAASESYGYNEDQIVSSDVVGIEYGSLFDATQTRVMTVGGKQLVKTVAWYDNEMSYT
CQLVRTLEYFAGKI
>Mature_333_residues
SIKVAINGFGRIGRLALRQIEKAHDIEVVAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDDAIVVNGKEIKVFANPNPE
ELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVISAPGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMAA
VLQKEFGVVEGLMTTIHAYTGDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPVATGS
LTELVSVLERPVTKEEINAAMKAAASESYGYNEDQIVSSDVVGIEYGSLFDATQTRVMTVGGKQLVKTVAWYDNEMSYTC
QLVRTLEYFAGKI

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=44.3452380952381, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI7657116, Length=338, Percent_Identity=45.5621301775148, Blast_Score=280, Evalue=2e-75,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=48.6567164179104, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=40.7185628742515, Blast_Score=253, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=47.3372781065089, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI32566163, Length=340, Percent_Identity=47.0588235294118, Blast_Score=286, Evalue=9e-78,
Organism=Caenorhabditis elegans, GI17568413, Length=340, Percent_Identity=47.0588235294118, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=47.3372781065089, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=46.1077844311377, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=44.9101796407186, Blast_Score=282, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=44.6107784431138, Blast_Score=280, Evalue=3e-76,
Organism=Drosophila melanogaster, GI17933600, Length=336, Percent_Identity=44.3452380952381, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI18110149, Length=336, Percent_Identity=44.3452380952381, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI85725000, Length=336, Percent_Identity=44.3452380952381, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI22023983, Length=336, Percent_Identity=44.3452380952381, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=42.5981873111783, Blast_Score=266, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35831; Mature: 35700

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKVAINGFGRIGRLALRQIEKAHDIEVVAVNDLTPAEMLLHLFKYDSTQGRFQGTAEL
CEEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCC
KDDAIVVNGKEIKVFANPNPEELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVIS
CCCEEEEECCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEEE
APGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMAAVLQKEFGVVEGLMTTIHAY
CCCCCCCEEEEEECCCHHCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPVATG
CCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCHHEEEEEEECCCCCCCCCCCEEEECCC
SLTELVSVLERPVTKEEINAAMKAAASESYGYNEDQIVSSDVVGIEYGSLFDATQTRVMT
CHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEECCCCCCCCCEEEEE
VGGKQLVKTVAWYDNEMSYTCQLVRTLEYFAGKI
ECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIKVAINGFGRIGRLALRQIEKAHDIEVVAVNDLTPAEMLLHLFKYDSTQGRFQGTAEL
EEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCC
KDDAIVVNGKEIKVFANPNPEELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVIS
CCCEEEEECCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEEE
APGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMAAVLQKEFGVVEGLMTTIHAY
CCCCCCCEEEEEECCCHHCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPVATG
CCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCHHEEEEEEECCCCCCCCCCCEEEECCC
SLTELVSVLERPVTKEEINAAMKAAASESYGYNEDQIVSSDVVGIEYGSLFDATQTRVMT
CHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEECCCCCCCCCEEEEE
VGGKQLVKTVAWYDNEMSYTCQLVRTLEYFAGKI
ECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10463150; 11466286 [H]