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The map label for this gene is etfA [H]

Identifier: 161871017

GI number: 161871017

Start: 2144644

End: 2145579

Strand: Reverse

Name: etfA [H]

Synonym: NMCC_2113

Alternate gene names: 161871017

Gene position: 2145579-2144644 (Counterclockwise)

Preceding gene: 161871018

Following gene: 161871016

Centisome position: 99.64

GC content: 48.08

Gene sequence:

>936_bases
ATGAGCGTATTGATTATTGCCGAACACGACAACAAACAGTTGAATCCTGCCACTTTGCATGCTGTTACCGCTGCCGCAAA
ACTAGGCAAAGTCGATTTATTGGTTGCCGGAAACGGCGCATCGTCCGTCGTGGAGTTCGCGAAGCAAGTAGCGGGAGTGG
AAAAAGTTTTGGTTGCAGATGCTGCCCATTATGCTGAAGGTTTGGCTGAAGAGTTGGCTCCGCTGGTTGTCAAATTGGCG
GCGGATTACCGCTATGTTGCAGCAACGGCAACCACATTCGGTAAAAACCTTTTGCCCCGCGTAGCCGCCTTATTAGACGT
ACCGCAAATTTCTGATTTGACCGAGATTGTAGATAACACGACTTTTGTACGTCCGATTTATGCAGGTAATGCATTTGAAA
CCGTGCAAGCCAATGCGGAAAAATTGGTGCTGACCTTCCGTGCGACGGCTTTTGACGCAGTGGCGGCGCAAGGTGGTAAT
GCTGAGGTAATTAATGTTGAAGCAACCCCTGCCCAAAACCTGAGTCGTTTTGTTAACCGTCAGCTTTCCCATTCCGATCG
TCCTGAACTGACTCAGGCAAAAGTGATTGTTTCCGGTGGTCGTGCGTTGGGTAGTGCGGAAAAATTCAATGAAGTGCTGA
CACCGTTGGCGGATGTTTTAGGTGCGGCAATCGGTGCATCCCGTGCAGCAGTTGATGCCGAATATGCGCCAAACGATGCT
CAAGTCGGACAAACCGGTAAAGTGGTTGCGCCGCAACTCTATTTTGCAATCGGTATTTCAGGTGCGATTCAACACGTTGC
CGGTATGCAAGACAGTAAGGTGATTGTTGCAATCAATAAAGATGCTGATGCGCCGATTTTCAATGTAGCCGATTACGGAT
TGGTTGGCGATTTATTTGAAATCGTTCCACAATTAACAGAAGCATTGAAAAATTGA

Upstream 100 bases:

>100_bases
GCCGAGCCTAAAGCGCGTCAGGCAGGCGTAAAAGTAGCAAGCGTTGCCGAATTAGTTGAAAAATTGAAAAACGAAGCCAA
AGTGATTTGAGGAGACTGAA

Downstream 100 bases:

>100_bases
TGTTTCACGTGAAACGTTCAGACGACCTTGTTATTAATGAGGTCGTCTGAAAACATTTCAGCATGATTACGACTTATAAA
ACCATTACCTCCTTGACGCA

Product: electron transfer flavoprotein alpha-subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSVLIIAEHDNKQLNPATLHAVTAAAKLGKVDLLVAGNGASSVVEFAKQVAGVEKVLVADAAHYAEGLAEELAPLVVKLA
ADYRYVAATATTFGKNLLPRVAALLDVPQISDLTEIVDNTTFVRPIYAGNAFETVQANAEKLVLTFRATAFDAVAAQGGN
AEVINVEATPAQNLSRFVNRQLSHSDRPELTQAKVIVSGGRALGSAEKFNEVLTPLADVLGAAIGASRAAVDAEYAPNDA
QVGQTGKVVAPQLYFAIGISGAIQHVAGMQDSKVIVAINKDADAPIFNVADYGLVGDLFEIVPQLTEALKN

Sequences:

>Translated_311_residues
MSVLIIAEHDNKQLNPATLHAVTAAAKLGKVDLLVAGNGASSVVEFAKQVAGVEKVLVADAAHYAEGLAEELAPLVVKLA
ADYRYVAATATTFGKNLLPRVAALLDVPQISDLTEIVDNTTFVRPIYAGNAFETVQANAEKLVLTFRATAFDAVAAQGGN
AEVINVEATPAQNLSRFVNRQLSHSDRPELTQAKVIVSGGRALGSAEKFNEVLTPLADVLGAAIGASRAAVDAEYAPNDA
QVGQTGKVVAPQLYFAIGISGAIQHVAGMQDSKVIVAINKDADAPIFNVADYGLVGDLFEIVPQLTEALKN
>Mature_310_residues
SVLIIAEHDNKQLNPATLHAVTAAAKLGKVDLLVAGNGASSVVEFAKQVAGVEKVLVADAAHYAEGLAEELAPLVVKLAA
DYRYVAATATTFGKNLLPRVAALLDVPQISDLTEIVDNTTFVRPIYAGNAFETVQANAEKLVLTFRATAFDAVAAQGGNA
EVINVEATPAQNLSRFVNRQLSHSDRPELTQAKVIVSGGRALGSAEKFNEVLTPLADVLGAAIGASRAAVDAEYAPNDAQ
VGQTGKVVAPQLYFAIGISGAIQHVAGMQDSKVIVAINKDADAPIFNVADYGLVGDLFEIVPQLTEALKN

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=313, Percent_Identity=55.2715654952077, Blast_Score=323, Evalue=9e-89,
Organism=Homo sapiens, GI189181759, Length=265, Percent_Identity=56.9811320754717, Blast_Score=289, Evalue=2e-78,
Organism=Escherichia coli, GI1787990, Length=257, Percent_Identity=33.0739299610895, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786226, Length=188, Percent_Identity=37.2340425531915, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082157, Length=216, Percent_Identity=32.8703703703704, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=53.8461538461538, Blast_Score=306, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6325261, Length=285, Percent_Identity=49.8245614035088, Blast_Score=270, Evalue=2e-73,
Organism=Drosophila melanogaster, GI17136898, Length=315, Percent_Identity=53.3333333333333, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24652801, Length=315, Percent_Identity=53.3333333333333, Blast_Score=303, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32465; Mature: 32334

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLIIAEHDNKQLNPATLHAVTAAAKLGKVDLLVAGNGASSVVEFAKQVAGVEKVLVAD
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
AAHYAEGLAEELAPLVVKLAADYRYVAATATTFGKNLLPRVAALLDVPQISDLTEIVDNT
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
TFVRPIYAGNAFETVQANAEKLVLTFRATAFDAVAAQGGNAEVINVEATPAQNLSRFVNR
CEEEEEECCCCHHHHHCCCEEEEEEEEHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHH
QLSHSDRPELTQAKVIVSGGRALGSAEKFNEVLTPLADVLGAAIGASRAAVDAEYAPNDA
HHCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
QVGQTGKVVAPQLYFAIGISGAIQHVAGMQDSKVIVAINKDADAPIFNVADYGLVGDLFE
CCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCHHHHHHH
IVPQLTEALKN
HHHHHHHHHCC
>Mature Secondary Structure 
SVLIIAEHDNKQLNPATLHAVTAAAKLGKVDLLVAGNGASSVVEFAKQVAGVEKVLVAD
EEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
AAHYAEGLAEELAPLVVKLAADYRYVAATATTFGKNLLPRVAALLDVPQISDLTEIVDNT
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
TFVRPIYAGNAFETVQANAEKLVLTFRATAFDAVAAQGGNAEVINVEATPAQNLSRFVNR
CEEEEEECCCCHHHHHCCCEEEEEEEEHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHH
QLSHSDRPELTQAKVIVSGGRALGSAEKFNEVLTPLADVLGAAIGASRAAVDAEYAPNDA
HHCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
QVGQTGKVVAPQLYFAIGISGAIQHVAGMQDSKVIVAINKDADAPIFNVADYGLVGDLFE
CCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCHHHHHHH
IVPQLTEALKN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]