Click here to switch to the map view.

The map label for this gene is comM [H]

Identifier: 161870669

GI number: 161870669

Start: 1784684

End: 1786141

Strand: Reverse

Name: comM [H]

Synonym: NMCC_1741

Alternate gene names: 161870669

Gene position: 1786141-1784684 (Counterclockwise)

Preceding gene: 161870670

Following gene: 161870668

Centisome position: 82.94

GC content: 59.19

Gene sequence:

>1458_bases
ATGAATGCGCCGTTGGTCGAAGTGGAAGCCCACCTTGCCAACGGCCTGCCACATTTCAACATCGTCGGGCTGCCCGATAC
GGAAGTCAAAGAAAGTCGCGACCGCGTCCGTGCCGCCATTATTCAAAGCGGTTTTGAATTCCCCGCCAAAAAAATCACCG
TCAACCTCGCCCCCGCCGACCTGCCCAAAGAGTCGGGGCGTTTCGATTTGCCGATTGCAATCGGCATCCTTGCTGCATCG
GGGCAGGTTGCGCCCGAAAAACTGGCGGAATACGAGTTTGCGGGGGAATTGGCACTGTCGGGGCTGTTGCGCCCCGTGCG
CGGCGCGTTGGCGATGGCGTGGCAGGGTATGCAGGCAAAACGTGCATTTGTTTTGCCTGAAGAAAACGCAGGACAAGCCG
CCGTGATGCGCGGCATTACCGTTTACGGCGCGCGCTCTTTGGGCGAAGTCGCCGCCCATTTGAACGGTATCGAACCTTTG
GCGCAAACCGAATGCCAAGTTCCTCAGATGCCGTTTGAACATGGCGGACAACCTGATTTGTGCGATGTGAAAGGTCAGCA
CACCGCGCGCCTTGCTTTGGAAATCGCTGCCGCAGGCGGACACAGCCTCTTGATGATGGGTCCGCCGGGAACGGGCAAGT
CTATGCTCTCCCAACGGCTGCCCGGCATCCTGCCGCCGCTGACCGAAGACGAATTGGTAGAAGTTTGGGCATTGCGTTCG
CTCCTGCCCAACCACCAACAACAACTCGACAGCAACCGTCCTTTCCGCAGTCCGCATCACAGCGCCAGCGCGGCGGCTAT
GGTCGGCGGCGGTTCGGATCCGCGTCCGGGCGAGATTTCATTGGCGCACCACGGCGTATTGTTTTTGGACGAGCTGCCCG
AGTTCGACCGCAAAGTTTTGGAAGTTTTGCGCGAACCGTTGGAAAACGGCGAAATCCACATTTCCCGCGCGGCGCGCCAA
GCCGTCTATCCTGCCAAATTCCAACTTGTTGCCGCCATGAACCCCTGCCCGTGCGGTTATCTCGGGCATCCCGTCAAACC
CTGCCGCTGCACGCCCGAAAGCGTCGCGCGTTACCGCAGCAAGATTTCCGGGCCGCTGCTCGACCGCATCGATTTGACCA
TCGAAGTCCCGAGCCTGTCCGCCGCCGAACTGATGCAGCAGGAAGCAGGGGAAAGGAGCGCGTCCGTTTTGGAACGCGTT
ATCGCCGCTAGAGACAAACAATACGCACGGCAAGGCAAAGTGAATGCCGCCTTGAGTGTCAGTGAACTCGACACATCCGC
CCGCATCCAAAAAGAAGCGCAGGAAGCATTGGGCAGCCTGCTGGAAAAACTCTCCCTTTCCGCCCGCAGCTTCCACCGCA
TTATGCGCGTGGCGCGTACATTGGCGGATTTGGCAGGCGACGAAGAAGTCGGCAGAAGCCACGTCATGAAAGCCATAGGT
TTCCGCCGTGCTTTATAG

Upstream 100 bases:

>100_bases
GAAGAAGCCGTCGCCGAAATCAGGCAGCAAACCGAAGCCGGCGAATAAGGCCGTCTGAAATATGTCGCTTGCCTTGGTTT
ACAGCCGCGCCTTGAGCGGT

Downstream 100 bases:

>100_bases
GAACGGGAATGGAAGCAGGTTTTGCCCAAATATGGCGATATTGTTAGAATATCCGCCCGTAAGCAAACGGCGTTAATGCC
GTCTGAAACACATTAAGGTA

Product: competence protein ComM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNAPLVEVEAHLANGLPHFNIVGLPDTEVKESRDRVRAAIIQSGFEFPAKKITVNLAPADLPKESGRFDLPIAIGILAAS
GQVAPEKLAEYEFAGELALSGLLRPVRGALAMAWQGMQAKRAFVLPEENAGQAAVMRGITVYGARSLGEVAAHLNGIEPL
AQTECQVPQMPFEHGGQPDLCDVKGQHTARLALEIAAAGGHSLLMMGPPGTGKSMLSQRLPGILPPLTEDELVEVWALRS
LLPNHQQQLDSNRPFRSPHHSASAAAMVGGGSDPRPGEISLAHHGVLFLDELPEFDRKVLEVLREPLENGEIHISRAARQ
AVYPAKFQLVAAMNPCPCGYLGHPVKPCRCTPESVARYRSKISGPLLDRIDLTIEVPSLSAAELMQQEAGERSASVLERV
IAARDKQYARQGKVNAALSVSELDTSARIQKEAQEALGSLLEKLSLSARSFHRIMRVARTLADLAGDEEVGRSHVMKAIG
FRRAL

Sequences:

>Translated_485_residues
MNAPLVEVEAHLANGLPHFNIVGLPDTEVKESRDRVRAAIIQSGFEFPAKKITVNLAPADLPKESGRFDLPIAIGILAAS
GQVAPEKLAEYEFAGELALSGLLRPVRGALAMAWQGMQAKRAFVLPEENAGQAAVMRGITVYGARSLGEVAAHLNGIEPL
AQTECQVPQMPFEHGGQPDLCDVKGQHTARLALEIAAAGGHSLLMMGPPGTGKSMLSQRLPGILPPLTEDELVEVWALRS
LLPNHQQQLDSNRPFRSPHHSASAAAMVGGGSDPRPGEISLAHHGVLFLDELPEFDRKVLEVLREPLENGEIHISRAARQ
AVYPAKFQLVAAMNPCPCGYLGHPVKPCRCTPESVARYRSKISGPLLDRIDLTIEVPSLSAAELMQQEAGERSASVLERV
IAARDKQYARQGKVNAALSVSELDTSARIQKEAQEALGSLLEKLSLSARSFHRIMRVARTLADLAGDEEVGRSHVMKAIG
FRRAL
>Mature_485_residues
MNAPLVEVEAHLANGLPHFNIVGLPDTEVKESRDRVRAAIIQSGFEFPAKKITVNLAPADLPKESGRFDLPIAIGILAAS
GQVAPEKLAEYEFAGELALSGLLRPVRGALAMAWQGMQAKRAFVLPEENAGQAAVMRGITVYGARSLGEVAAHLNGIEPL
AQTECQVPQMPFEHGGQPDLCDVKGQHTARLALEIAAAGGHSLLMMGPPGTGKSMLSQRLPGILPPLTEDELVEVWALRS
LLPNHQQQLDSNRPFRSPHHSASAAAMVGGGSDPRPGEISLAHHGVLFLDELPEFDRKVLEVLREPLENGEIHISRAARQ
AVYPAKFQLVAAMNPCPCGYLGHPVKPCRCTPESVARYRSKISGPLLDRIDLTIEVPSLSAAELMQQEAGERSASVLERV
IAARDKQYARQGKVNAALSVSELDTSARIQKEAQEALGSLLEKLSLSARSFHRIMRVARTLADLAGDEEVGRSHVMKAIG
FRRAL

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=485, Percent_Identity=49.2783505154639, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 52279; Mature: 52279

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLVEVEAHLANGLPHFNIVGLPDTEVKESRDRVRAAIIQSGFEFPAKKITVNLAPAD
CCCCEEEHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
LPKESGRFDLPIAIGILAASGQVAPEKLAEYEFAGELALSGLLRPVRGALAMAWQGMQAK
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RAFVLPEENAGQAAVMRGITVYGARSLGEVAAHLNGIEPLAQTECQVPQMPFEHGGQPDL
CEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHCCCCCCC
CDVKGQHTARLALEIAAAGGHSLLMMGPPGTGKSMLSQRLPGILPPLTEDELVEVWALRS
CCCCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LLPNHQQQLDSNRPFRSPHHSASAAAMVGGGSDPRPGEISLAHHGVLFLDELPEFDRKVL
HCCCHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCEEEEHHCCHHHHHHH
EVLREPLENGEIHISRAARQAVYPAKFQLVAAMNPCPCGYLGHPVKPCRCTPESVARYRS
HHHHHHHHCCCEEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
KISGPLLDRIDLTIEVPSLSAAELMQQEAGERSASVLERVIAARDKQYARQGKVNAALSV
HHCCCCHHHEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEH
SELDTSARIQKEAQEALGSLLEKLSLSARSFHRIMRVARTLADLAGDEEVGRSHVMKAIG
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FRRAL
HHHCC
>Mature Secondary Structure
MNAPLVEVEAHLANGLPHFNIVGLPDTEVKESRDRVRAAIIQSGFEFPAKKITVNLAPAD
CCCCEEEHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
LPKESGRFDLPIAIGILAASGQVAPEKLAEYEFAGELALSGLLRPVRGALAMAWQGMQAK
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RAFVLPEENAGQAAVMRGITVYGARSLGEVAAHLNGIEPLAQTECQVPQMPFEHGGQPDL
CEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHCCCCCCC
CDVKGQHTARLALEIAAAGGHSLLMMGPPGTGKSMLSQRLPGILPPLTEDELVEVWALRS
CCCCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LLPNHQQQLDSNRPFRSPHHSASAAAMVGGGSDPRPGEISLAHHGVLFLDELPEFDRKVL
HCCCHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCEEEEHHCCHHHHHHH
EVLREPLENGEIHISRAARQAVYPAKFQLVAAMNPCPCGYLGHPVKPCRCTPESVARYRS
HHHHHHHHCCCEEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
KISGPLLDRIDLTIEVPSLSAAELMQQEAGERSASVLERVIAARDKQYARQGKVNAALSV
HHCCCCHHHEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEH
SELDTSARIQKEAQEALGSLLEKLSLSARSFHRIMRVARTLADLAGDEEVGRSHVMKAIG
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FRRAL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]