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The map label for this gene is mraW [H]

Identifier: 161870663

GI number: 161870663

Start: 1778707

End: 1779501

Strand: Reverse

Name: mraW [H]

Synonym: NMCC_1733

Alternate gene names: 161870663

Gene position: 1779501-1778707 (Counterclockwise)

Preceding gene: 161870664

Following gene: 161870662

Centisome position: 82.64

GC content: 57.11

Gene sequence:

>795_bases
GTGGCAGAAGAGCTGGCGCGTTCGGACAAACGGGTCGGTGTCGTGCATGGCGGTTTTGCTTCGTTTCAGACGGCATTGGA
CGGTTTGGGTATCGGCAAGGTGGACGGTGCGCTGTTTGATTTGGGGATTTCGTCTCCGCAAATCGATGACGGCAGCCGCG
GTTTCAGCTTTCGTTTCGATGCCCCTTTGGATATGCGTATGGATACGATGCGCGGTATGTCTGCCGCAGAGTGGATAGCG
GTTGCGTCGGAACAGGATTTGCACGAGGTAATCAAGAATTATGGTGAAGAGCGGTTTAGCCGCCAGATTGCGCGCGCCAT
TGTTGCGCAACGGGCGGAAAGTCCAATCGATACAACCCGCAAGCTGGCGCAGATCGTGGCACAAAACGTCCGTACTCGCG
AGCGGGGGCAGGATCCTGCGACGCGCACCTTCCAGGCAATCCGCATCTTTATTAACCGCGAGCTTGAAGAAGTAGGGGCA
GTATTGCCGCAGGTCATGTGTCGTCTGAAAGAGGGCGGACGTTTGGCGGTCATTGCTTTCCATTCGTTGGAAGACCGCAT
TGTGAAGCAGTTTGTCAAAAAATATTCGCAACACGCGCCCCTGCCGCGCTGGGCGGCGGTCAGGGAAGCGGATTTGCCCG
AGCCGCCCCTGAAAATCGCGGGCAGGGCATTAAAGCCGGGTGAGGCGGAAATTGCCGCCAATCCGAGGGCGAGAAGTGCG
GTTTTGCGTGTGGCGGAGCGGACTGCCGGTCCGATACCGGAACAATCACAGAGAAAAACGTCTGAATGGCAATGA

Upstream 100 bases:

>100_bases
CGGTACGTTCGGCAGGGGAGGGCATTCCCGGCTGATTTTGTCGCGTTTGGGCGATGCGGGGCGGTTGATTGTTTTCGACA
AAGACCCGCAGGCGATTGCT

Downstream 100 bases:

>100_bases
ACAAATTGAATTTCCTTCTGCTGCTTGCGGTGTGCGTTTCCGCTTTTTCCGTTGTGATGCAGCAAAACCAGTACAGGCTC
AACTTCACAGCTTTGGATAA

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MAEELARSDKRVGVVHGGFASFQTALDGLGIGKVDGALFDLGISSPQIDDGSRGFSFRFDAPLDMRMDTMRGMSAAEWIA
VASEQDLHEVIKNYGEERFSRQIARAIVAQRAESPIDTTRKLAQIVAQNVRTRERGQDPATRTFQAIRIFINRELEEVGA
VLPQVMCRLKEGGRLAVIAFHSLEDRIVKQFVKKYSQHAPLPRWAAVREADLPEPPLKIAGRALKPGEAEIAANPRARSA
VLRVAERTAGPIPEQSQRKTSEWQ

Sequences:

>Translated_264_residues
MAEELARSDKRVGVVHGGFASFQTALDGLGIGKVDGALFDLGISSPQIDDGSRGFSFRFDAPLDMRMDTMRGMSAAEWIA
VASEQDLHEVIKNYGEERFSRQIARAIVAQRAESPIDTTRKLAQIVAQNVRTRERGQDPATRTFQAIRIFINRELEEVGA
VLPQVMCRLKEGGRLAVIAFHSLEDRIVKQFVKKYSQHAPLPRWAAVREADLPEPPLKIAGRALKPGEAEIAANPRARSA
VLRVAERTAGPIPEQSQRKTSEWQ
>Mature_263_residues
AEELARSDKRVGVVHGGFASFQTALDGLGIGKVDGALFDLGISSPQIDDGSRGFSFRFDAPLDMRMDTMRGMSAAEWIAV
ASEQDLHEVIKNYGEERFSRQIARAIVAQRAESPIDTTRKLAQIVAQNVRTRERGQDPATRTFQAIRIFINRELEEVGAV
LPQVMCRLKEGGRLAVIAFHSLEDRIVKQFVKKYSQHAPLPRWAAVREADLPEPPLKIAGRALKPGEAEIAANPRARSAV
LRVAERTAGPIPEQSQRKTSEWQ

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=280, Percent_Identity=38.2142857142857, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI165377202, Length=138, Percent_Identity=40.5797101449275, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786270, Length=247, Percent_Identity=49.7975708502024, Blast_Score=234, Evalue=3e-63,
Organism=Drosophila melanogaster, GI62472493, Length=251, Percent_Identity=41.8326693227092, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28571637, Length=251, Percent_Identity=41.8326693227092, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 29267; Mature: 29136

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEELARSDKRVGVVHGGFASFQTALDGLGIGKVDGALFDLGISSPQIDDGSRGFSFRFD
CCHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEC
APLDMRMDTMRGMSAAEWIAVASEQDLHEVIKNYGEERFSRQIARAIVAQRAESPIDTTR
CCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KLAQIVAQNVRTRERGQDPATRTFQAIRIFINRELEEVGAVLPQVMCRLKEGGRLAVIAF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
HSLEDRIVKQFVKKYSQHAPLPRWAAVREADLPEPPLKIAGRALKPGEAEIAANPRARSA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHH
VLRVAERTAGPIPEQSQRKTSEWQ
HHHHHHHHCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
AEELARSDKRVGVVHGGFASFQTALDGLGIGKVDGALFDLGISSPQIDDGSRGFSFRFD
CHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEC
APLDMRMDTMRGMSAAEWIAVASEQDLHEVIKNYGEERFSRQIARAIVAQRAESPIDTTR
CCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KLAQIVAQNVRTRERGQDPATRTFQAIRIFINRELEEVGAVLPQVMCRLKEGGRLAVIAF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
HSLEDRIVKQFVKKYSQHAPLPRWAAVREADLPEPPLKIAGRALKPGEAEIAANPRARSA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHH
VLRVAERTAGPIPEQSQRKTSEWQ
HHHHHHHHCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA