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The map label for this gene is aroC [H]

Identifier: 161870528

GI number: 161870528

Start: 1622403

End: 1623503

Strand: Direct

Name: aroC [H]

Synonym: NMCC_1593

Alternate gene names: 161870528

Gene position: 1622403-1623503 (Clockwise)

Preceding gene: 161870524

Following gene: 161870529

Centisome position: 75.34

GC content: 59.13

Gene sequence:

>1101_bases
ATGGCAGGCAACACTTTCGGACAACTCTTCACCGTGACCACGTTCGGCGAAAGCCACGGCGCAGGTTTGGGCTGCATCAT
CGACGGCTGCCCGCCCGGCTTGGAATTAAGCGAAGCGGATATCCAATTTGACCTCGACCGACGCAAACCCGGCACCAGCC
GCCACGTTACCCAACGCCGCGAAACCGACCAAGTAGAAATCCTCTCCGGCGTATTCAAAGGCAAAACCACCGGCACGCCC
ATCGCCCTCTTAATCCGCAATACCGACCAGCGCAGCAAAGACTACGGCAACATCGCCCAAAGTTTCCGCCCCGGCCATGC
CGACTATACCTATTGGCACAAATACGGCACGCGCGACTACCGCGGCGGCGGCAGGAGCTCCGCCCGTGAAACCGCCGCCC
GCGTTGCTGCCGGAGCCGTTGCCAAAAAATGGTTGAAAGAAAAATTCGGCACGGAAATCACCGCCTACGTTACCCAAGTC
GGCGAAAAAGAAATCCGGTTTGAAGGCTGCGAACACATTTCCCAAAATCCTTTTTTTGCCGCCAACCATAGCCAAATTGC
CGAGCTGGAAAACTATATGGACAGCGTGCGCAAATCGTTGGATTCCGTCGGCGCGAAGCTGCATATTGAAGCCGCCAATG
TCCCCGTCGGCTTGGGCGAACCCGTTTTCGACCGCCTCGATGCCGAAATCGCCTACGCGATGATGGGCATCAACGCCGTA
AAAGGCGTGGAAATCGGCGCAGGTTTTGACAGCGTAACGCAACGCGGCAGCGAACACGGCGACGAACTGACCCCGCAAGG
CTTCCTGTCCAACCATTCGGGCGGCATCCTCGGCGGCATCAGTACCGGGCAAGACATCTGCGTCAATATCGCCATCAAAC
CCACCAGCTCCATCGCCACCCCGCGCCGCAGTATCGACATCAACGGCAACCCCATCGAACTCGCCACGCACGGCAGGCAC
GACCCCTGCGTCGGCTTGCGCGCCGCGCCGATTGCCGAAGCTATGCTCGCCTTGGTTTTAATCGACCACGCCCTGCGCCA
TCGTGCGCAAAATGCGGATGTTGCCGTGGATACGCCCGATATCGCCCGCTCGGACAAGTAA

Upstream 100 bases:

>100_bases
CTGCAAAACACGCAACCCCTTTACCGGCATATAACCCGTTTTCCTCCAACTTTTATGCTAAAATCCGCCGTCTCCAACAT
ACCGCCGACAGAAGGAAAAT

Downstream 100 bases:

>100_bases
AAAGATTTAGCCAAAACACGGGCTTTATACTAAAATACCGACCATTGCCGTGCCGTCTGAACGCACGATTCTTAGAGGAA
TACAACCGAAATGACACAAG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MAGNTFGQLFTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFDLDRRKPGTSRHVTQRRETDQVEILSGVFKGKTTGTP
IALLIRNTDQRSKDYGNIAQSFRPGHADYTYWHKYGTRDYRGGGRSSARETAARVAAGAVAKKWLKEKFGTEITAYVTQV
GEKEIRFEGCEHISQNPFFAANHSQIAELENYMDSVRKSLDSVGAKLHIEAANVPVGLGEPVFDRLDAEIAYAMMGINAV
KGVEIGAGFDSVTQRGSEHGDELTPQGFLSNHSGGILGGISTGQDICVNIAIKPTSSIATPRRSIDINGNPIELATHGRH
DPCVGLRAAPIAEAMLALVLIDHALRHRAQNADVAVDTPDIARSDK

Sequences:

>Translated_366_residues
MAGNTFGQLFTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFDLDRRKPGTSRHVTQRRETDQVEILSGVFKGKTTGTP
IALLIRNTDQRSKDYGNIAQSFRPGHADYTYWHKYGTRDYRGGGRSSARETAARVAAGAVAKKWLKEKFGTEITAYVTQV
GEKEIRFEGCEHISQNPFFAANHSQIAELENYMDSVRKSLDSVGAKLHIEAANVPVGLGEPVFDRLDAEIAYAMMGINAV
KGVEIGAGFDSVTQRGSEHGDELTPQGFLSNHSGGILGGISTGQDICVNIAIKPTSSIATPRRSIDINGNPIELATHGRH
DPCVGLRAAPIAEAMLALVLIDHALRHRAQNADVAVDTPDIARSDK
>Mature_365_residues
AGNTFGQLFTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFDLDRRKPGTSRHVTQRRETDQVEILSGVFKGKTTGTPI
ALLIRNTDQRSKDYGNIAQSFRPGHADYTYWHKYGTRDYRGGGRSSARETAARVAAGAVAKKWLKEKFGTEITAYVTQVG
EKEIRFEGCEHISQNPFFAANHSQIAELENYMDSVRKSLDSVGAKLHIEAANVPVGLGEPVFDRLDAEIAYAMMGINAVK
GVEIGAGFDSVTQRGSEHGDELTPQGFLSNHSGGILGGISTGQDICVNIAIKPTSSIATPRRSIDINGNPIELATHGRHD
PCVGLRAAPIAEAMLALVLIDHALRHRAQNADVAVDTPDIARSDK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=65.7381615598886, Blast_Score=466, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6321290, Length=373, Percent_Identity=43.9678284182306, Blast_Score=300, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39394; Mature: 39262

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNTFGQLFTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFDLDRRKPGTSRHVTQRR
CCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHC
ETDQVEILSGVFKGKTTGTPIALLIRNTDQRSKDYGNIAQSFRPGHADYTYWHKYGTRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCHHCHHHHHHHHHCCCCCCCCCCEECCCCCCC
RGGGRSSARETAARVAAGAVAKKWLKEKFGTEITAYVTQVGEKEIRFEGCEHISQNPFFA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
ANHSQIAELENYMDSVRKSLDSVGAKLHIEAANVPVGLGEPVFDRLDAEIAYAMMGINAV
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHH
KGVEIGAGFDSVTQRGSEHGDELTPQGFLSNHSGGILGGISTGQDICVNIAIKPTSSIAT
CCEEECCCHHHHHHCCHHCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCCCC
PRRSIDINGNPIELATHGRHDPCVGLRAAPIAEAMLALVLIDHALRHRAQNADVAVDTPD
CCCEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
IARSDK
CCCCCC
>Mature Secondary Structure 
AGNTFGQLFTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFDLDRRKPGTSRHVTQRR
CCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHC
ETDQVEILSGVFKGKTTGTPIALLIRNTDQRSKDYGNIAQSFRPGHADYTYWHKYGTRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCHHCHHHHHHHHHCCCCCCCCCCEECCCCCCC
RGGGRSSARETAARVAAGAVAKKWLKEKFGTEITAYVTQVGEKEIRFEGCEHISQNPFFA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
ANHSQIAELENYMDSVRKSLDSVGAKLHIEAANVPVGLGEPVFDRLDAEIAYAMMGINAV
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHH
KGVEIGAGFDSVTQRGSEHGDELTPQGFLSNHSGGILGGISTGQDICVNIAIKPTSSIAT
CCEEECCCHHHHHHCCHHCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCCCC
PRRSIDINGNPIELATHGRHDPCVGLRAAPIAEAMLALVLIDHALRHRAQNADVAVDTPD
CCCEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
IARSDK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA