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The map label for this gene is gpmA [H]

Identifier: 161870454

GI number: 161870454

Start: 1534275

End: 1534958

Strand: Reverse

Name: gpmA [H]

Synonym: NMCC_1509

Alternate gene names: 161870454

Gene position: 1534958-1534275 (Counterclockwise)

Preceding gene: 161870459

Following gene: 161870449

Centisome position: 71.28

GC content: 55.41

Gene sequence:

>684_bases
ATGGAACTGGTATTTATCCGCCACGGACAAAGCGAATGGAACGCGAAAAACCTGTTTACAGGCTGGCGCGACGTGAAGCT
GAGCGAGCAGGGGCTTGCCGAGGCTGCCGCCGCCGGTAAAAAACTGAAAGAAAACGGCTATGAGTTCGACATCGCCTTCA
CATCCGTCCTGACCCGCGCGATTAAGACCTGCAACATCGTTTTGGAAGAATCCGACCAACTGTTCGTACCGCAAATCAAA
ACGTGGCGGCTGAACGAACGCCACTACGGCCAACTGCAAGGCCTGGACAAAAAACAAACCGCCGAAAAATACGGCGACGA
GCAAGTCCGCATCTGGCGGCGCAGCTACGACACCCTGCCGCCGCTTTTGGACAAAGACGATGAGTTTTCCGCACACAAAG
ACCGCCGCTATGCCCATCTGCCTGCCGATGTCGTACCCGACGGCGAAAACCTGAAAGTAACGCTGGAGCGCGTATTGCCG
TTTTGGGAAGACCAAATCGCCCCCGCGATTTTGAGCGGCAAACGCGTCTTGGTGGCGGCGCACGGCAACTCCCTGCGCGC
GCTGGCAAAACACATCGAGGGCATTTCCGACGAAGACATTATGGGCTTGGAAATCCCGACCGGTCAGCCGCTGGTGTACA
AATTGGATGACAACCTGAAAGTCCTCGAAAAATTCTACCTGTAA

Upstream 100 bases:

>100_bases
GCAAACCATAGTGGGCGCGTGTCTGAATCTGAATCAAATACGGGAAATGTGAAAATATGTTATAAATAAGGCTTTCCCAC
TTTCACACATTGGAGACGAT

Downstream 100 bases:

>100_bases
GGGTTTGAAATAAAAAATGCCGTCTGAAGGCTTGAGCGTTCAGACGGCATTTTTGACGGTAAACGTAGCAACTGCTTTCG
CGAGAACGACGAGATTTTAG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAIKTCNIVLEESDQLFVPQIK
TWRLNERHYGQLQGLDKKQTAEKYGDEQVRIWRRSYDTLPPLLDKDDEFSAHKDRRYAHLPADVVPDGENLKVTLERVLP
FWEDQIAPAILSGKRVLVAAHGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDNLKVLEKFYL

Sequences:

>Translated_227_residues
MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAIKTCNIVLEESDQLFVPQIK
TWRLNERHYGQLQGLDKKQTAEKYGDEQVRIWRRSYDTLPPLLDKDDEFSAHKDRRYAHLPADVVPDGENLKVTLERVLP
FWEDQIAPAILSGKRVLVAAHGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDNLKVLEKFYL
>Mature_227_residues
MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAIKTCNIVLEESDQLFVPQIK
TWRLNERHYGQLQGLDKKQTAEKYGDEQVRIWRRSYDTLPPLLDKDDEFSAHKDRRYAHLPADVVPDGENLKVTLERVLP
FWEDQIAPAILSGKRVLVAAHGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDNLKVLEKFYL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=220, Percent_Identity=53.6363636363636, Blast_Score=252, Evalue=2e-67,
Organism=Homo sapiens, GI4505753, Length=221, Percent_Identity=56.5610859728507, Blast_Score=251, Evalue=3e-67,
Organism=Homo sapiens, GI71274132, Length=224, Percent_Identity=54.0178571428571, Blast_Score=241, Evalue=4e-64,
Organism=Homo sapiens, GI4502445, Length=225, Percent_Identity=49.3333333333333, Blast_Score=238, Evalue=3e-63,
Organism=Homo sapiens, GI40353764, Length=225, Percent_Identity=49.3333333333333, Blast_Score=238, Evalue=3e-63,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=54.0372670807453, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI1786970, Length=226, Percent_Identity=57.0796460176991, Blast_Score=271, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6322697, Length=225, Percent_Identity=55.1111111111111, Blast_Score=261, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6320183, Length=281, Percent_Identity=32.7402135231317, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324516, Length=276, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6324857, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646216, Length=223, Percent_Identity=56.5022421524664, Blast_Score=259, Evalue=1e-69,
Organism=Drosophila melanogaster, GI85725270, Length=222, Percent_Identity=53.6036036036036, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI85725272, Length=222, Percent_Identity=53.6036036036036, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24650981, Length=222, Percent_Identity=53.6036036036036, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI28571815, Length=217, Percent_Identity=40.0921658986175, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28571817, Length=217, Percent_Identity=40.0921658986175, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24648979, Length=217, Percent_Identity=40.0921658986175, Blast_Score=175, Evalue=2e-44,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25959; Mature: 25959

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRA
CEEEEEECCCCCCCCHHHCCCCCCCEECHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
IKTCNIVLEESDQLFVPQIKTWRLNERHYGQLQGLDKKQTAEKYGDEQVRIWRRSYDTLP
HHHHEEEEECCCCEECCCCEEEEECCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCC
PLLDKDDEFSAHKDRRYAHLPADVVPDGENLKVTLERVLPFWEDQIAPAILSGKRVLVAA
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEHHHHCCHHHHHHCHHHHCCCEEEEEE
HGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDNLKVLEKFYL
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRA
CEEEEEECCCCCCCCHHHCCCCCCCEECHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
IKTCNIVLEESDQLFVPQIKTWRLNERHYGQLQGLDKKQTAEKYGDEQVRIWRRSYDTLP
HHHHEEEEECCCCEECCCCEEEEECCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCC
PLLDKDDEFSAHKDRRYAHLPADVVPDGENLKVTLERVLPFWEDQIAPAILSGKRVLVAA
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEHHHHCCHHHHHHCHHHHCCCEEEEEE
HGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDNLKVLEKFYL
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA