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The map label for this gene is pgsA [H]

Identifier: 161870443

GI number: 161870443

Start: 1520962

End: 1521576

Strand: Reverse

Name: pgsA [H]

Synonym: NMCC_1498

Alternate gene names: 161870443

Gene position: 1521576-1520962 (Counterclockwise)

Preceding gene: 161870444

Following gene: 161870442

Centisome position: 70.66

GC content: 48.13

Gene sequence:

>615_bases
ATGAGGATAACCGTTATAATCACAACTTTACAGTCTGCACAGAGAAAACCGATGCCTTGGAATCTCCCCATCTTCCTCAC
ATGGTTGAGGGTCTTGCTCATTCCTGTCATGACAGCCCTTTTTTACCTGCCTTTTCCGTGGTTCGCGGAGGAAACGATTA
ATCTTGCCGCCGCCGTCATTTTTGCCGTTGCCGCCTTAACCGACTGGTTTGACGGATTTTTGGCAAGACTGTGGAAACAG
ACTTCCGATTTCGGCGCCTTCCTCGATCCCGTTGCCGACAAGCTGATGGTCGCCGTCTCTTTGCTTTTACTGGTCAAACT
CGACCGGACCTATGTTTTGTTTGCCATGATCATCATCGGCAGGGAAATTACCATTTCCGCATTGCGCGAATGGATGGCGC
AAATGGGCAAAAGGAACAGCGTTGCCGTCGCCACCGTCGGTAAGTTTAAAACCGCCGCGCAAATGCTGGCAATTTTCCTG
CTGCTGCTGAATATTCCCGATTTTTACGGATTTAATCTTGTTGTTATCGGCAATGTATTGATGTTTATCGCATCTTTGCT
GACAGTCTGGTCGATGCTGTATTATCTGAAAATGGCGTGGAAAGAAATCGCCTGA

Upstream 100 bases:

>100_bases
TTTGCTTTTATTGCCCGCCATTTTCCTGCGTTTGAAAAGAATGTGAAAACAGATTGGCGGGGCGGGGGAATGCCCATGCA
GCAATTTTACGTTTTGGGTT

Downstream 100 bases:

>100_bases
AAAAAACATAAAAATAGCTTGACGGCAAAAACAGAATCCATAATAATTGCGTCTCTTCGATGTTGGAGAATGAAATCGGG
CGGGAATAGCTCAGTTGGTA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MRITVIITTLQSAQRKPMPWNLPIFLTWLRVLLIPVMTALFYLPFPWFAEETINLAAAVIFAVAALTDWFDGFLARLWKQ
TSDFGAFLDPVADKLMVAVSLLLLVKLDRTYVLFAMIIIGREITISALREWMAQMGKRNSVAVATVGKFKTAAQMLAIFL
LLLNIPDFYGFNLVVIGNVLMFIASLLTVWSMLYYLKMAWKEIA

Sequences:

>Translated_204_residues
MRITVIITTLQSAQRKPMPWNLPIFLTWLRVLLIPVMTALFYLPFPWFAEETINLAAAVIFAVAALTDWFDGFLARLWKQ
TSDFGAFLDPVADKLMVAVSLLLLVKLDRTYVLFAMIIIGREITISALREWMAQMGKRNSVAVATVGKFKTAAQMLAIFL
LLLNIPDFYGFNLVVIGNVLMFIASLLTVWSMLYYLKMAWKEIA
>Mature_204_residues
MRITVIITTLQSAQRKPMPWNLPIFLTWLRVLLIPVMTALFYLPFPWFAEETINLAAAVIFAVAALTDWFDGFLARLWKQ
TSDFGAFLDPVADKLMVAVSLLLLVKLDRTYVLFAMIIIGREITISALREWMAQMGKRNSVAVATVGKFKTAAQMLAIFL
LLLNIPDFYGFNLVVIGNVLMFIASLLTVWSMLYYLKMAWKEIA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=106, Percent_Identity=38.6792452830189, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI10092647, Length=106, Percent_Identity=38.6792452830189, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788220, Length=184, Percent_Identity=51.6304347826087, Blast_Score=166, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 23190; Mature: 23190

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITVIITTLQSAQRKPMPWNLPIFLTWLRVLLIPVMTALFYLPFPWFAEETINLAAAVI
CEEEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FAVAALTDWFDGFLARLWKQTSDFGAFLDPVADKLMVAVSLLLLVKLDRTYVLFAMIIIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
REITISALREWMAQMGKRNSVAVATVGKFKTAAQMLAIFLLLLNIPDFYGFNLVVIGNVL
CHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MFIASLLTVWSMLYYLKMAWKEIA
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRITVIITTLQSAQRKPMPWNLPIFLTWLRVLLIPVMTALFYLPFPWFAEETINLAAAVI
CEEEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FAVAALTDWFDGFLARLWKQTSDFGAFLDPVADKLMVAVSLLLLVKLDRTYVLFAMIIIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
REITISALREWMAQMGKRNSVAVATVGKFKTAAQMLAIFLLLLNIPDFYGFNLVVIGNVL
CHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MFIASLLTVWSMLYYLKMAWKEIA
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]