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The map label for this gene is dipZ [H]

Identifier: 161870379

GI number: 161870379

Start: 1447267

End: 1449108

Strand: Reverse

Name: dipZ [H]

Synonym: NMCC_1425

Alternate gene names: 161870379

Gene position: 1449108-1447267 (Counterclockwise)

Preceding gene: 161870381

Following gene: 161870376

Centisome position: 67.29

GC content: 55.16

Gene sequence:

>1842_bases
ATGCAGACAAATTATTTGTCTGAAACGGATTCGATTATGAAAAAACTGATTTGCCTGTTCGCCGTATTTTTGATGTTGTG
CGGACGAGCTTTCGCGCTGGATGCGAACGATCTGCTGCCGCCGGAAAAGGCATTCGTGCCGGAGCTTGCCGTTGCCGACG
ACGGTGTGAACGTCCGTTTCAGGATTGCCGACGGATACTATATGTATCAGGCGAAAATCGTCGGCAAGACCGATCCGGCG
GATTTGTTGGGACAGCCTTCTTTCAGCAAGGGTGAAGAGAAGGAAGACGAGTTTTTCGGCAGGCAGACGGTTTACCATCA
CGAAGCGCAGGTTGCCTTTCCTTATGCAAAGGCTGTCGGCGAACCGTATAAATTGGTTTTGACCTATCAGGGCTGTGCCG
AAGCCGGCGTGTGCTATCCGCCCGTGGATACCGAGTTTGATATTTCCGGCAACGGCACTTACCATCCGCAAACCGACGAA
CCGGCATCCGCCAAAGACCGCTTTTTGCAGCCTTCCTCTCAAAACGGCAGCGGGGTGCTGCCGCCCCCGAAGGGGGATGA
GGGCGGCGACAGCCGTTTCAAGCTGTCTTGGGATACGCTCAACGCCAATCTTTTGGCGTTTTTTCTCGCCGGTTTGGGTC
TGAGTTTTACCGCCTGTATGTATCCCCTGTTGCCGATTGTTTCCAGTATTGTGGTCGGCGACAAAAAGGCGGGCAAGGCG
CGGGCGTTTGTGCTGTCCGTCGTTTATGTTCAGGGTTTGGCTCTGACTTATACGCTGGTCGGCATTGTTGCCGGACTGAC
GGGCGCACTGCTGACCGTATGGTTGCAGCAGGCTTGGGTGGTGTTGGCGGCATCGGCTTTAATGGTCGTCTTGGCACTGT
CTATGTTCGGGCTGTTCAACATCCAGCTTCCCAACGCCGTGCAGTCGTATTTTCAGAATCAAAGCAGCAGGCTTTCAGGC
GGTAAAATCGTTTCCGTCTTTATTATGGGCATATTGTCCGCGCTGATTGTCGGGCCGTGCGTCGCCCCGCCGCTGGCATT
TGCTTTGGGCTACATCGGTCAGACGGGCGATGCGGTTTTAGGCGGTTTGGCACTTTACACTTTGGCGTTGGGCACCGGCG
TTCCGCTGATTGCCATCGGCACGTTCGGCGGGCATATCCTGCCTAAGGCAGGCGATTGGATGAATGCCGTCAAATACGCT
TTCGGCTTTATCCTGCTTGCCGTCGCCGTTTACCTCGCCACGCCGCACTTGCCCTATTATCTCGTCGTCGCGCTGTACAC
GCTGCTGATGCTGGTTCCTGCCTGTATGCTGCTGGTCAACGGACGCAGGCAGAAACGCCGTCCGAAAGCTGTGGCATTCG
TATTGGGCGGCATATTGCTGATAGGCGGCGCGTGGTTCGGCTGGCAGGGCGCAAACGGCAAAACGACCGCGCTGCACCAT
TTCCTGACCCTCAATCCGCCGGCTGAAGCAGGCAAATCTTCGGAACACGGAAAAATGTTTGCCGATACTGCCGCGCTGAA
GGCAGCGATGGATACGGCGTTGAAAGAACATCCTGACAAACCCGTCGTTTTGGATTTTTATGCCGACTGGTGCATTTCCT
GCAAAGAAATGGCGGCTTACACGCTCAATCAGCCGGAAGTGCATCAGGCAGTCGATATGGAACGCTTTTTCCAAATCGAT
GTAACCGCCAACATGCCCGAACATCAGGCGTTGTTGAAAGAATACGGTCTGTTCGGGCCGCCGGGCGTGTTTGTCGTCCG
CTCCGACGGCAGCCGCAGCGAGCCGCTGCTGGGTTTTGTCAAAGCAGACAAGTTTATCGAGTGGTATGAACAAAACCGCT
GA

Upstream 100 bases:

>100_bases
CATCGTACATGGCGGGTTCGATAAGATGTTTATGGAAATAGGTTCGGATAATGGCGGGTTTTACATAAATTAAATCCCAC
CGTCAACCTTACCATTTATA

Downstream 100 bases:

>100_bases
TTCCGATGTTTCAAATGCCGTCTGAAGTTCTCAGACGGCATTTTTGTCAGAAAGGAAAACGGCAATATCCACTATACACA
CGGAAGCAGTCCAAAGATGT

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MQTNYLSETDSIMKKLICLFAVFLMLCGRAFALDANDLLPPEKAFVPELAVADDGVNVRFRIADGYYMYQAKIVGKTDPA
DLLGQPSFSKGEEKEDEFFGRQTVYHHEAQVAFPYAKAVGEPYKLVLTYQGCAEAGVCYPPVDTEFDISGNGTYHPQTDE
PASAKDRFLQPSSQNGSGVLPPPKGDEGGDSRFKLSWDTLNANLLAFFLAGLGLSFTACMYPLLPIVSSIVVGDKKAGKA
RAFVLSVVYVQGLALTYTLVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRLSG
GKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIAIGTFGGHILPKAGDWMNAVKYA
FGFILLAVAVYLATPHLPYYLVVALYTLLMLVPACMLLVNGRRQKRRPKAVAFVLGGILLIGGAWFGWQGANGKTTALHH
FLTLNPPAEAGKSSEHGKMFADTAALKAAMDTALKEHPDKPVVLDFYADWCISCKEMAAYTLNQPEVHQAVDMERFFQID
VTANMPEHQALLKEYGLFGPPGVFVVRSDGSRSEPLLGFVKADKFIEWYEQNR

Sequences:

>Translated_613_residues
MQTNYLSETDSIMKKLICLFAVFLMLCGRAFALDANDLLPPEKAFVPELAVADDGVNVRFRIADGYYMYQAKIVGKTDPA
DLLGQPSFSKGEEKEDEFFGRQTVYHHEAQVAFPYAKAVGEPYKLVLTYQGCAEAGVCYPPVDTEFDISGNGTYHPQTDE
PASAKDRFLQPSSQNGSGVLPPPKGDEGGDSRFKLSWDTLNANLLAFFLAGLGLSFTACMYPLLPIVSSIVVGDKKAGKA
RAFVLSVVYVQGLALTYTLVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRLSG
GKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIAIGTFGGHILPKAGDWMNAVKYA
FGFILLAVAVYLATPHLPYYLVVALYTLLMLVPACMLLVNGRRQKRRPKAVAFVLGGILLIGGAWFGWQGANGKTTALHH
FLTLNPPAEAGKSSEHGKMFADTAALKAAMDTALKEHPDKPVVLDFYADWCISCKEMAAYTLNQPEVHQAVDMERFFQID
VTANMPEHQALLKEYGLFGPPGVFVVRSDGSRSEPLLGFVKADKFIEWYEQNR
>Mature_613_residues
MQTNYLSETDSIMKKLICLFAVFLMLCGRAFALDANDLLPPEKAFVPELAVADDGVNVRFRIADGYYMYQAKIVGKTDPA
DLLGQPSFSKGEEKEDEFFGRQTVYHHEAQVAFPYAKAVGEPYKLVLTYQGCAEAGVCYPPVDTEFDISGNGTYHPQTDE
PASAKDRFLQPSSQNGSGVLPPPKGDEGGDSRFKLSWDTLNANLLAFFLAGLGLSFTACMYPLLPIVSSIVVGDKKAGKA
RAFVLSVVYVQGLALTYTLVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRLSG
GKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIAIGTFGGHILPKAGDWMNAVKYA
FGFILLAVAVYLATPHLPYYLVVALYTLLMLVPACMLLVNGRRQKRRPKAVAFVLGGILLIGGAWFGWQGANGKTTALHH
FLTLNPPAEAGKSSEHGKMFADTAALKAAMDTALKEHPDKPVVLDFYADWCISCKEMAAYTLNQPEVHQAVDMERFFQID
VTANMPEHQALLKEYGLFGPPGVFVVRSDGSRSEPLLGFVKADKFIEWYEQNR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=598, Percent_Identity=32.2742474916388, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 66292; Mature: 66292

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTNYLSETDSIMKKLICLFAVFLMLCGRAFALDANDLLPPEKAFVPELAVADDGVNVRF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHCCCCEEECCCCEEEE
RIADGYYMYQAKIVGKTDPADLLGQPSFSKGEEKEDEFFGRQTVYHHEAQVAFPYAKAVG
EEECCEEEEEEEEECCCCCHHHCCCCCCCCCCCHHHHHHCCHHEEECCCCEECHHHHHCC
EPYKLVLTYQGCAEAGVCYPPVDTEFDISGNGTYHPQTDEPASAKDRFLQPSSQNGSGVL
CCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
PPPKGDEGGDSRFKLSWDTLNANLLAFFLAGLGLSFTACMYPLLPIVSSIVVGDKKAGKA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RAFVLSVVYVQGLALTYTLVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
IQLPNAVQSYFQNQSSRLSGGKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVL
EECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHH
GGLALYTLALGTGVPLIAIGTFGGHILPKAGDWMNAVKYAFGFILLAVAVYLATPHLPYY
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LVVALYTLLMLVPACMLLVNGRRQKRRPKAVAFVLGGILLIGGAWFGWQGANGKTTALHH
HHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
FLTLNPPAEAGKSSEHGKMFADTAALKAAMDTALKEHPDKPVVLDFYADWCISCKEMAAY
EEEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHH
TLNQPEVHQAVDMERFFQIDVTANMPEHQALLKEYGLFGPPGVFVVRSDGSRSEPLLGFV
CCCCCHHHHHHCHHHHEEEEEECCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEEHH
KADKFIEWYEQNR
HHHHHHHHHHCCC
>Mature Secondary Structure
MQTNYLSETDSIMKKLICLFAVFLMLCGRAFALDANDLLPPEKAFVPELAVADDGVNVRF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHCCCCEEECCCCEEEE
RIADGYYMYQAKIVGKTDPADLLGQPSFSKGEEKEDEFFGRQTVYHHEAQVAFPYAKAVG
EEECCEEEEEEEEECCCCCHHHCCCCCCCCCCCHHHHHHCCHHEEECCCCEECHHHHHCC
EPYKLVLTYQGCAEAGVCYPPVDTEFDISGNGTYHPQTDEPASAKDRFLQPSSQNGSGVL
CCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCC
PPPKGDEGGDSRFKLSWDTLNANLLAFFLAGLGLSFTACMYPLLPIVSSIVVGDKKAGKA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RAFVLSVVYVQGLALTYTLVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
IQLPNAVQSYFQNQSSRLSGGKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVL
EECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHH
GGLALYTLALGTGVPLIAIGTFGGHILPKAGDWMNAVKYAFGFILLAVAVYLATPHLPYY
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LVVALYTLLMLVPACMLLVNGRRQKRRPKAVAFVLGGILLIGGAWFGWQGANGKTTALHH
HHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
FLTLNPPAEAGKSSEHGKMFADTAALKAAMDTALKEHPDKPVVLDFYADWCISCKEMAAY
EEEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHH
TLNQPEVHQAVDMERFFQIDVTANMPEHQALLKEYGLFGPPGVFVVRSDGSRSEPLLGFV
CCCCCHHHHHHCHHHHEEEEEECCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEEHH
KADKFIEWYEQNR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]