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The map label for this gene is dnaQ [H]

Identifier: 161870374

GI number: 161870374

Start: 1442532

End: 1443095

Strand: Reverse

Name: dnaQ [H]

Synonym: NMCC_1419

Alternate gene names: 161870374

Gene position: 1443095-1442532 (Counterclockwise)

Preceding gene: 161871034

Following gene: 161871033

Centisome position: 67.01

GC content: 58.33

Gene sequence:

>564_bases
GTGCACGGTCTGACGATAGAGGTTTTGGAAGGGAAAAACGCGCCGCCGTTTGCAGAGGTCGGCAGGCAGATTGCCGATTT
CCTGCGCGGTGCGGAGTTGATTATCCACAATGCCAAATTCGACGTGGGCTTCCTCAATATGGAGTTCCGCCGGATGGGGT
TGCCGACTGTCGAGGAACTCGGCTGTACCGTTACCGATACCCTGGCGATGGCGCGCGAAATGTTCCCTGGGCAGAAAGCC
AGCCTGGATGCCCTGTGCAACCGTTTTTCCGTCGACCGCAGCAAGCGCGTCCTGCACGGCGCATTGATCGACTGCGAACT
TTTGGGCGAAGTCTATCTTGCTATGACGCGGCGGCAGTTCGACCTGATGGGGGAGGCCGCAGAGGAAAAAATGGAAACCA
AACCCGTGGTGCATACCGAAACCAAACGCAGCGGCAAACTGAAAGTCATCAGGGCGGACGAAAACGAGTTGGCGGCGCAC
GGGCAATATTTGGACGGCTTGGGCGAAGCCTGTATCTGGCGCAAGGAAGCCGTGCCGTCTGAAAACGGCGGGACGGACGC
ATGA

Upstream 100 bases:

>100_bases
CGAGTTTGCCGGTTTAGAAATGGTCAACCGCCAAATGACCGACAAAAACCTGCACCTCTATGTCCACCCCGAGCGCGATA
TGCCCGAAGAGGCGGCGAGG

Downstream 100 bases:

>100_bases
AGCGCAAAAATATCGCGCTGATTCCCGCCGCCGGCATCGGGGCGCGTTTCGGTGCGGACAAACCCAAGCAATATGTCGAA
ATCGGAAGCAAAACCGTTTT

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MHGLTIEVLEGKNAPPFAEVGRQIADFLRGAELIIHNAKFDVGFLNMEFRRMGLPTVEELGCTVTDTLAMAREMFPGQKA
SLDALCNRFSVDRSKRVLHGALIDCELLGEVYLAMTRRQFDLMGEAAEEKMETKPVVHTETKRSGKLKVIRADENELAAH
GQYLDGLGEACIWRKEAVPSENGGTDA

Sequences:

>Translated_187_residues
MHGLTIEVLEGKNAPPFAEVGRQIADFLRGAELIIHNAKFDVGFLNMEFRRMGLPTVEELGCTVTDTLAMAREMFPGQKA
SLDALCNRFSVDRSKRVLHGALIDCELLGEVYLAMTRRQFDLMGEAAEEKMETKPVVHTETKRSGKLKVIRADENELAAH
GQYLDGLGEACIWRKEAVPSENGGTDA
>Mature_187_residues
MHGLTIEVLEGKNAPPFAEVGRQIADFLRGAELIIHNAKFDVGFLNMEFRRMGLPTVEELGCTVTDTLAMAREMFPGQKA
SLDALCNRFSVDRSKRVLHGALIDCELLGEVYLAMTRRQFDLMGEAAEEKMETKPVVHTETKRSGKLKVIRADENELAAH
GQYLDGLGEACIWRKEAVPSENGGTDA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=183, Percent_Identity=45.3551912568306, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 20693; Mature: 20693

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGLTIEVLEGKNAPPFAEVGRQIADFLRGAELIIHNAKFDVGFLNMEFRRMGLPTVEEL
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHHCCCCCHHHH
GCTVTDTLAMAREMFPGQKASLDALCNRFSVDRSKRVLHGALIDCELLGEVYLAMTRRQF
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLMGEAAEEKMETKPVVHTETKRSGKLKVIRADENELAAHGQYLDGLGEACIWRKEAVPS
HHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCCC
ENGGTDA
CCCCCCC
>Mature Secondary Structure
MHGLTIEVLEGKNAPPFAEVGRQIADFLRGAELIIHNAKFDVGFLNMEFRRMGLPTVEEL
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHHCCCCCHHHH
GCTVTDTLAMAREMFPGQKASLDALCNRFSVDRSKRVLHGALIDCELLGEVYLAMTRRQF
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLMGEAAEEKMETKPVVHTETKRSGKLKVIRADENELAAHGQYLDGLGEACIWRKEAVPS
HHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCCC
ENGGTDA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]