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The map label for this gene is trpD

Identifier: 161869879

GI number: 161869879

Start: 917682

End: 918740

Strand: Direct

Name: trpD

Synonym: NMCC_0910

Alternate gene names: 161869879

Gene position: 917682-918740 (Clockwise)

Preceding gene: 229597121

Following gene: 161869880

Centisome position: 42.62

GC content: 52.88

Gene sequence:

>1059_bases
ATGATTACACCGCAACAGGCTATCGAACGATTAATCAGCAATAACGAGTTGTTTTACGATGAAATGACCGACTTGATGCG
GCAAATGATGAGCGGAAAAGTGCCGCCCGAACAAATTGCGGCGATTTTGACAGGATTGCGTATCAAGGTTGAAACCGTTT
CCGAAATTACCGCCGCCGCCGCCGTCATGCGCGAGTTTGCGACAAAAGTGCCGCTGGAGAATGCAGAGGGGCTGGTCGAT
ATCGTCGGTACGGGCGGGGATGGCGCGAAAACCTTCAATATTTCGACGACTTCGATGTTTGTTGCCGCAGCGGCAGGCGC
GAAGGTTGCCAAACACGGAGGCCGGTCGGTCTCTTCCTCCAGCGGTGCGGCTGACGTGGTGGAGCAGATGGGCGCAAACC
TCAACCTGACTCCCGAACAGGTTGCCCAAAGTATCAGGCAGACCGGCATCGGGTTTATGTTCGCGCCCAATCACCACAGT
GCCATGCGCCATGTCGCCCCTGTACGCCGTTCGCTCGGTTTCCGAAGTATTTTCAACATATTGGGTCCGTTAACGAATCC
TGCGGGCGCGCCGAACCAGCTTTTGGGCGTGTTCCACACCGATTTGTGCGGCATTTTGTCGCGGGTCTTGCAACAACTTG
GTTCAAAACACGTTTTGGTTGTTTGTGGGGAGGGCGGTTTGGATGAAATTACACTGACAGGCAAAACGCGCGTTGCCGAA
CTCAAAGACGGAAAAATCAGCGAATACGACATCCGCCCAGAAGATTTCGGTATCGAAACCCGCCGCAATTTGGATGAAAT
CAAAGTTGCCAATACTCAGGAATCTTTGTTGAAAATGAATGAGGTGCTGGAAGGAAGAGAAGGGGCTGCGCGCGATATCG
TATTGCTCAACACCGCCGCCGCCCTGTATGCCGGAAATGTCGCTGCTTCGCTTTCAGACGGCATATCTGCCGCACGGGAA
GCCATCGATTCAGGCAGGGCCAAATCGAAAAAAGAGGAGTTTGTCGGTTTTCAACCACAACAAAGATGCCATTTTCTTGG
AAAGATGGAGCTTGGGTGA

Upstream 100 bases:

>100_bases
AGTTGAATTTCAAAACTTCAAACCGCAAAAAATCTGACGTGATGCCGTCTGAATCCCTTCAGACGGCATTTTCGTCCGAA
TATTGAACGGAGGACAAAAA

Downstream 100 bases:

>100_bases
TGCCGCCATGATTATGGAACTTTTGTGGCAAAACATAAGCACTTCACGAAGAGAACTTACCAAACTGTTTTTATATAAAA
ACTTGGGGCTGTACTAGATA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MITPQQAIERLISNNELFYDEMTDLMRQMMSGKVPPEQIAAILTGLRIKVETVSEITAAAAVMREFATKVPLENAEGLVD
IVGTGGDGAKTFNISTTSMFVAAAAGAKVAKHGGRSVSSSSGAADVVEQMGANLNLTPEQVAQSIRQTGIGFMFAPNHHS
AMRHVAPVRRSLGFRSIFNILGPLTNPAGAPNQLLGVFHTDLCGILSRVLQQLGSKHVLVVCGEGGLDEITLTGKTRVAE
LKDGKISEYDIRPEDFGIETRRNLDEIKVANTQESLLKMNEVLEGREGAARDIVLLNTAAALYAGNVAASLSDGISAARE
AIDSGRAKSKKEEFVGFQPQQRCHFLGKMELG

Sequences:

>Translated_352_residues
MITPQQAIERLISNNELFYDEMTDLMRQMMSGKVPPEQIAAILTGLRIKVETVSEITAAAAVMREFATKVPLENAEGLVD
IVGTGGDGAKTFNISTTSMFVAAAAGAKVAKHGGRSVSSSSGAADVVEQMGANLNLTPEQVAQSIRQTGIGFMFAPNHHS
AMRHVAPVRRSLGFRSIFNILGPLTNPAGAPNQLLGVFHTDLCGILSRVLQQLGSKHVLVVCGEGGLDEITLTGKTRVAE
LKDGKISEYDIRPEDFGIETRRNLDEIKVANTQESLLKMNEVLEGREGAARDIVLLNTAAALYAGNVAASLSDGISAARE
AIDSGRAKSKKEEFVGFQPQQRCHFLGKMELG
>Mature_352_residues
MITPQQAIERLISNNELFYDEMTDLMRQMMSGKVPPEQIAAILTGLRIKVETVSEITAAAAVMREFATKVPLENAEGLVD
IVGTGGDGAKTFNISTTSMFVAAAAGAKVAKHGGRSVSSSSGAADVVEQMGANLNLTPEQVAQSIRQTGIGFMFAPNHHS
AMRHVAPVRRSLGFRSIFNILGPLTNPAGAPNQLLGVFHTDLCGILSRVLQQLGSKHVLVVCGEGGLDEITLTGKTRVAE
LKDGKISEYDIRPEDFGIETRRNLDEIKVANTQESLLKMNEVLEGREGAARDIVLLNTAAALYAGNVAASLSDGISAARE
AIDSGRAKSKKEEFVGFQPQQRCHFLGKMELG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=284, Percent_Identity=40.4929577464789, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320561, Length=326, Percent_Identity=31.5950920245399, Blast_Score=146, Evalue=5e-36,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_NEIM0 (A9M4G6)

Other databases:

- EMBL:   CP000381
- RefSeq:   YP_001599048.1
- EnsemblBacteria:   EBNEIT00000012887
- GeneID:   5796159
- GenomeReviews:   CP000381_GR
- KEGG:   nmn:NMCC_0910
- GeneTree:   EBGT00050000020527
- HOGENOM:   HBG559996
- OMA:   GSADIME
- ProtClustDB:   PRK00188
- BioCyc:   NMEN374833:NMCC_0910-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37632; Mature: 37632

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITPQQAIERLISNNELFYDEMTDLMRQMMSGKVPPEQIAAILTGLRIKVETVSEITAAA
CCCHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEHHHHHHHHHH
AVMREFATKVPLENAEGLVDIVGTGGDGAKTFNISTTSMFVAAAAGAKVAKHGGRSVSSS
HHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHCHHHHHCCCCCCCCC
SGAADVVEQMGANLNLTPEQVAQSIRQTGIGFMFAPNHHSAMRHVAPVRRSLGFRSIFNI
CCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHH
LGPLTNPAGAPNQLLGVFHTDLCGILSRVLQQLGSKHVLVVCGEGGLDEITLTGKTRVAE
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCEEEE
LKDGKISEYDIRPEDFGIETRRNLDEIKVANTQESLLKMNEVLEGREGAARDIVLLNTAA
CCCCCCCCCCCCCCCCCCHHHCCHHHHEECCHHHHHHHHHHHHCCCCCCCCCEEEEEHHH
ALYAGNVAASLSDGISAAREAIDSGRAKSKKEEFVGFQPQQRCHFLGKMELG
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MITPQQAIERLISNNELFYDEMTDLMRQMMSGKVPPEQIAAILTGLRIKVETVSEITAAA
CCCHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEHHHHHHHHHH
AVMREFATKVPLENAEGLVDIVGTGGDGAKTFNISTTSMFVAAAAGAKVAKHGGRSVSSS
HHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHCHHHHHCCCCCCCCC
SGAADVVEQMGANLNLTPEQVAQSIRQTGIGFMFAPNHHSAMRHVAPVRRSLGFRSIFNI
CCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHH
LGPLTNPAGAPNQLLGVFHTDLCGILSRVLQQLGSKHVLVVCGEGGLDEITLTGKTRVAE
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCEEEE
LKDGKISEYDIRPEDFGIETRRNLDEIKVANTQESLLKMNEVLEGREGAARDIVLLNTAA
CCCCCCCCCCCCCCCCCCHHHCCHHHHEECCHHHHHHHHHHHHCCCCCCCCCEEEEEHHH
ALYAGNVAASLSDGISAAREAIDSGRAKSKKEEFVGFQPQQRCHFLGKMELG
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA