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The map label for this gene is gltA [H]

Identifier: 161869866

GI number: 161869866

Start: 896531

End: 897814

Strand: Direct

Name: gltA [H]

Synonym: NMCC_0897

Alternate gene names: 161869866

Gene position: 896531-897814 (Clockwise)

Preceding gene: 161869865

Following gene: 161869867

Centisome position: 41.63

GC content: 52.88

Gene sequence:

>1284_bases
ATGTCCAAATCAATCAAACTCAACGTACCGGGTCAGGCAGGTTTGGAGCTGCCGGTATTGGAAGCCAGCATCGGGCACGA
TGTGGTTGACATTCGGGGGCTGACAAAAAATACAGGTTTGTTTTCCTTCGACCCCGGATTTGTTTCAACCGCAAGCTGTG
AGTCTAAAATTACTTACATCGACGGCGATCAAGGCTTGCTTTATTATCGCGGATACCCCATCGAGCAGCTGGCCGAAAAG
TCCGATTATTTGGAAGTCTGCTACCTGTTGATTTACGGCGAACTGCCGACTCCCGAGCAAAAGGCAGAATTTGACAATAC
CGTCCGCCGCCACACGATGGTGCATGAACAGCTGACTTGGTTCTTCCGGGGGTTCCGCCGCGACGCGCATCCGATGGCGA
TGATGGTCGGCGTGGTCGGTGCGCTGTCTGCGTTCTACCAAGACAGCTTGGACATTAGCAATCCCGAACACCGCAAAATC
GCGATTTACCGCCTGATTTCCAAAATCCCGACCATTGCGGCAATGTGCTACCGCTATTCAAACGGTCTGCCGTTCAATTA
TCCGAAGAATAATCTTTCTTATTCCGAAAACTTCCTTCATATGATGTTCGCCACGCCGTGTGAAGACTACAAACCCAATC
CCGTTTTGGCACGCGCGCTCGACCGCATCTTTATTTTGCATGCCGACCACGAGCAAAACGCCTCAACTTCAACCGTCCGT
CTGGCAGGGTCTTCGGGTGCGAACCCGTTTGCCTGTATTGCTGCCGGTATCGCCTGCCTGTGGGGTGCTTCGCACGGCGG
TGCGAACGAAGCCGTGTTGAAAATGTTGGACGAAATCGGCGATGTGTCTAATGTTGCCGCATACATGGAAGGTGTGAAAC
AACGCAAATACCGTCTGATGGGCTTCGGTCACCGCGTGTACCGCAATATGGATCCGCGTGCCAGCATTATGCGCGAAACC
TGCTATGAAGTTTTGAAGGAATTGGGCTTGGAAGACAGTCCGAAATTCAAACTGGCGATGGAATTGGAACAGATTGCGCT
GAAAGACCCGTTCTTTATCGAACGCAAACTGTATCCAAACGTCGATTTCTATTCCGGCATCGTCCTGTCCGCGCTGGGCA
TCCCGACCGAAATGTTTACCGTCATCTTCGCCCTGTCGCGCAGCGTGGGCTGGATTTCGCACTGGCACGAGATGATTAGC
GATCCTTCGCTGAAAATCGGCCGCCCGCGCCAGCTTTATACCGGTTCGGAACGCCGCGATTATGTGCCGCCAGGCGAGAG
GTAA

Upstream 100 bases:

>100_bases
TCTGCCTGCAGGCAGATTTCAAAATGCAAAAGCCGTCTGAAGGCAAAGAACGTGCTGCGGATGCAGTAACGTGGGTTATA
ACTTGCAAAGGAGCAATAAT

Downstream 100 bases:

>100_bases
CATACATTAATATATTGTCAAACAGGCAATATCAGAGAACCGGATTGTTTCCCGAATCCGTCTGATTGTAGTCGGATGAA
ATCAAGACAAGCAATCCGGT

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSKSIKLNVPGQAGLELPVLEASIGHDVVDIRGLTKNTGLFSFDPGFVSTASCESKITYIDGDQGLLYYRGYPIEQLAEK
SDYLEVCYLLIYGELPTPEQKAEFDNTVRRHTMVHEQLTWFFRGFRRDAHPMAMMVGVVGALSAFYQDSLDISNPEHRKI
AIYRLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLARALDRIFILHADHEQNASTSTVR
LAGSSGANPFACIAAGIACLWGASHGGANEAVLKMLDEIGDVSNVAAYMEGVKQRKYRLMGFGHRVYRNMDPRASIMRET
CYEVLKELGLEDSPKFKLAMELEQIALKDPFFIERKLYPNVDFYSGIVLSALGIPTEMFTVIFALSRSVGWISHWHEMIS
DPSLKIGRPRQLYTGSERRDYVPPGER

Sequences:

>Translated_427_residues
MSKSIKLNVPGQAGLELPVLEASIGHDVVDIRGLTKNTGLFSFDPGFVSTASCESKITYIDGDQGLLYYRGYPIEQLAEK
SDYLEVCYLLIYGELPTPEQKAEFDNTVRRHTMVHEQLTWFFRGFRRDAHPMAMMVGVVGALSAFYQDSLDISNPEHRKI
AIYRLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLARALDRIFILHADHEQNASTSTVR
LAGSSGANPFACIAAGIACLWGASHGGANEAVLKMLDEIGDVSNVAAYMEGVKQRKYRLMGFGHRVYRNMDPRASIMRET
CYEVLKELGLEDSPKFKLAMELEQIALKDPFFIERKLYPNVDFYSGIVLSALGIPTEMFTVIFALSRSVGWISHWHEMIS
DPSLKIGRPRQLYTGSERRDYVPPGER
>Mature_426_residues
SKSIKLNVPGQAGLELPVLEASIGHDVVDIRGLTKNTGLFSFDPGFVSTASCESKITYIDGDQGLLYYRGYPIEQLAEKS
DYLEVCYLLIYGELPTPEQKAEFDNTVRRHTMVHEQLTWFFRGFRRDAHPMAMMVGVVGALSAFYQDSLDISNPEHRKIA
IYRLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLARALDRIFILHADHEQNASTSTVRL
AGSSGANPFACIAAGIACLWGASHGGANEAVLKMLDEIGDVSNVAAYMEGVKQRKYRLMGFGHRVYRNMDPRASIMRETC
YEVLKELGLEDSPKFKLAMELEQIALKDPFFIERKLYPNVDFYSGIVLSALGIPTEMFTVIFALSRSVGWISHWHEMISD
PSLKIGRPRQLYTGSERRDYVPPGER

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=412, Percent_Identity=28.6407766990291, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI1786939, Length=418, Percent_Identity=66.5071770334928, Blast_Score=603, Evalue=1e-174,
Organism=Escherichia coli, GI1786527, Length=362, Percent_Identity=30.1104972375691, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17555174, Length=389, Percent_Identity=27.7634961439589, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319850, Length=372, Percent_Identity=26.0752688172043, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324328, Length=370, Percent_Identity=27.2972972972973, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325257, Length=413, Percent_Identity=25.4237288135593, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640126, Length=414, Percent_Identity=26.5700483091787, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24640124, Length=413, Percent_Identity=26.634382566586, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356863, Length=401, Percent_Identity=27.1820448877805, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48122; Mature: 47991

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSIKLNVPGQAGLELPVLEASIGHDVVDIRGLTKNTGLFSFDPGFVSTASCESKITYI
CCCCEEEECCCCCCCCCEEEHHHCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEE
DGDQGLLYYRGYPIEQLAEKSDYLEVCYLLIYGELPTPEQKAEFDNTVRRHTMVHEQLTW
ECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FFRGFRRDAHPMAMMVGVVGALSAFYQDSLDISNPEHRKIAIYRLISKIPTIAAMCYRYS
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLARALDRIFILHADHEQNASTSTVR
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIACLWGASHGGANEAVLKMLDEIGDVSNVAAYMEGVKQRKYRLM
EECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFGHRVYRNMDPRASIMRETCYEVLKELGLEDSPKFKLAMELEQIALKDPFFIERKLYPN
CCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCCCCCEEEHCCCCC
VDFYSGIVLSALGIPTEMFTVIFALSRSVGWISHWHEMISDPSLKIGRPRQLYTGSERRD
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
YVPPGER
CCCCCCC
>Mature Secondary Structure 
SKSIKLNVPGQAGLELPVLEASIGHDVVDIRGLTKNTGLFSFDPGFVSTASCESKITYI
CCCEEEECCCCCCCCCEEEHHHCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEE
DGDQGLLYYRGYPIEQLAEKSDYLEVCYLLIYGELPTPEQKAEFDNTVRRHTMVHEQLTW
ECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FFRGFRRDAHPMAMMVGVVGALSAFYQDSLDISNPEHRKIAIYRLISKIPTIAAMCYRYS
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLARALDRIFILHADHEQNASTSTVR
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIACLWGASHGGANEAVLKMLDEIGDVSNVAAYMEGVKQRKYRLM
EECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFGHRVYRNMDPRASIMRETCYEVLKELGLEDSPKFKLAMELEQIALKDPFFIERKLYPN
CCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCCCCCEEEHCCCCC
VDFYSGIVLSALGIPTEMFTVIFALSRSVGWISHWHEMISDPSLKIGRPRQLYTGSERRD
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
YVPPGER
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2507528; 10984043 [H]