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The map label for this gene is cspA [H]

Identifier: 161869773

GI number: 161869773

Start: 807735

End: 807977

Strand: Direct

Name: cspA [H]

Synonym: NMCC_0796

Alternate gene names: 161869773

Gene position: 807735-807977 (Clockwise)

Preceding gene: 161871030

Following gene: 161869775

Centisome position: 37.51

GC content: 44.03

Gene sequence:

>243_bases
TTGCTGATTTTGTTAATTTTTGAGTATAGGAAGTTTCTAATGGCAACCGGTATCGTAAAATGGTTTAACGACGCTAAAGG
TTTTGGTTTCATCACGCCTGATGAAGGCGGCGAAGATTTGTTCGCTCACTTCTCAGCAATCAATATGGAAGGTTTCAAAA
CCCTGAAAGAAGGCCAACGTGTCTCTTTCGACGTAACCACCGGCCCTAAAGGCAAACAGGCCGCCAACATTCAGGCTGCT
TAA

Upstream 100 bases:

>100_bases
CTTAACAAATGTAAAAAGACGGTTAAGCAGGATTGGGCATCCGCCGAGTATATCAAGCTGGAAGGAACGCCAGACGGCTC
GGTTTGCCGTATGCCTTGTT

Downstream 100 bases:

>100_bases
TTCCTGATGTACGGTCAAATGTATATTTGAAAACGGCGGGACAGGCAATGTCCCGCCGTTTTTGTCTGCCGTTTTGCCGG
CGGCGGAAAAACCCCAATCC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 80

Protein sequence:

>80_residues
MLILLIFEYRKFLMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMEGFKTLKEGQRVSFDVTTGPKGKQAANIQAA

Sequences:

>Translated_80_residues
MLILLIFEYRKFLMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMEGFKTLKEGQRVSFDVTTGPKGKQAANIQAA
>Mature_80_residues
MLILLIFEYRKFLMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMEGFKTLKEGQRVSFDVTTGPKGKQAANIQAA

Specific function: Inhibits DNA Replication At Both Initiation And Elongation Steps, Most Probably By Binding To The Opened, Single- Stranded Regions At Replication Forks. Plays A Regulatory Role In Chromosomal Replication In Nutrient-Depleted Cells. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1787107, Length=64, Percent_Identity=64.0625, Blast_Score=92, Evalue=5e-21,
Organism=Escherichia coli, GI1786841, Length=63, Percent_Identity=65.0793650793651, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI1789979, Length=64, Percent_Identity=60.9375, Blast_Score=88, Evalue=1e-19,
Organism=Escherichia coli, GI1788126, Length=63, Percent_Identity=60.3174603174603, Blast_Score=82, Evalue=9e-18,
Organism=Escherichia coli, GI1787834, Length=64, Percent_Identity=57.8125, Blast_Score=80, Evalue=2e-17,
Organism=Escherichia coli, GI2367114, Length=62, Percent_Identity=56.4516129032258, Blast_Score=80, Evalue=2e-17,
Organism=Escherichia coli, GI1787839, Length=62, Percent_Identity=56.4516129032258, Blast_Score=80, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71983225, Length=56, Percent_Identity=51.7857142857143, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71983217, Length=56, Percent_Identity=51.7857142857143, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24658520, Length=63, Percent_Identity=42.8571428571429, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 8876; Mature: 8876

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILLIFEYRKFLMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMEGFKTLKEGQR
CEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCE
VSFDVTTGPKGKQAANIQAA
EEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLILLIFEYRKFLMATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMEGFKTLKEGQR
CEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCE
VSFDVTTGPKGKQAANIQAA
EEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA