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The map label for this gene is xerD [H]

Identifier: 161869695

GI number: 161869695

Start: 721591

End: 722466

Strand: Direct

Name: xerD [H]

Synonym: NMCC_0715

Alternate gene names: 161869695

Gene position: 721591-722466 (Clockwise)

Preceding gene: 161869694

Following gene: 161869696

Centisome position: 33.51

GC content: 55.14

Gene sequence:

>876_bases
ATGGAAGAAGGTTTGATCGACAGGCTGCTTGAAACGCTGTGGTTGGACAGGCGGCTCAATCAGAATACTTTAAACGGTTA
CCGGCGCGATTTGGAAAAAATCGCCCGCCGCCTGTCCCAATCGGGCAGAACGCTGAAGGATGCGGACGAAGCGGATTTGG
CGGCGGCGGTTTATGTTGACGGAGAGCAACGGAGTTCGCAGGCGCGCGCATTATCGGCGTGCAAACGCCTGTATATATGG
ATGGAGCGTGAAGGCATAAGGACGGACAATCCCACCCGTTTGCTGAAACCGCCCAAAATCGACAAGAATATTCCGACCCT
GATCACCGAGCAGCAGATTTCCCGACTGCTTGCCACTCCGGATACTGATACGCCACACGGTTTGCGGGACAAGGCACTGC
TCGAATTGATGTACGCGACCGGCTTGCGCGTCAGCGAGGCGGTCGGGCTGAACTTCGGCAATGTGGATTTGGACAGGGGC
TGTATTACCGCGCTGGGCAAGGGCGATAAGCAGAGGATGGTCCCGATGGGGCAGGAGTCGGCGTATTGGGTGGAACGCTA
TTATACGGAGGCACGCCCACTTCTGCTGAAAGGCAGGAATTGCGACGCATTGTTTGTCAGTCAGAAAAAGACGGGCATTT
CTCGTCAGTTGGCATGGATGATTGTCAAAGAATATGCAGGTAGGGCGGGCATCGGGCACATCAGCCCGCACAGCCTGCGC
CACGCCTTTGCCACGCACTTGGTGCAGCACGGATTGGATTTGCGCGTGGTTCAGGATATGTTGGGACATGCCGATTTGAA
TACGACGCAGATTTACACCCATGTTGCCAATGTATGGTTGCAGGGTGTAGTGAAGGAACACCATTCCCGAAACTGA

Upstream 100 bases:

>100_bases
CAAAGTGGCGGGTCATGCACAGGAAGTGTTGGAAACGCTTTCCCGATAATGTGAACCATGCCGCCTGAAGAAGATTCAGA
CGGCATTTGTTTGGAACGGT

Downstream 100 bases:

>100_bases
GGCTTCTGCTTCGGTTTAATAAGAAATCAATCGGAAATGAAAACTTGATAAAAAATTACCAAGATAAACCGTGTATGCCG
ACCTTGCAATGCGAACCGTT

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MEEGLIDRLLETLWLDRRLNQNTLNGYRRDLEKIARRLSQSGRTLKDADEADLAAAVYVDGEQRSSQARALSACKRLYIW
MEREGIRTDNPTRLLKPPKIDKNIPTLITEQQISRLLATPDTDTPHGLRDKALLELMYATGLRVSEAVGLNFGNVDLDRG
CITALGKGDKQRMVPMGQESAYWVERYYTEARPLLLKGRNCDALFVSQKKTGISRQLAWMIVKEYAGRAGIGHISPHSLR
HAFATHLVQHGLDLRVVQDMLGHADLNTTQIYTHVANVWLQGVVKEHHSRN

Sequences:

>Translated_291_residues
MEEGLIDRLLETLWLDRRLNQNTLNGYRRDLEKIARRLSQSGRTLKDADEADLAAAVYVDGEQRSSQARALSACKRLYIW
MEREGIRTDNPTRLLKPPKIDKNIPTLITEQQISRLLATPDTDTPHGLRDKALLELMYATGLRVSEAVGLNFGNVDLDRG
CITALGKGDKQRMVPMGQESAYWVERYYTEARPLLLKGRNCDALFVSQKKTGISRQLAWMIVKEYAGRAGIGHISPHSLR
HAFATHLVQHGLDLRVVQDMLGHADLNTTQIYTHVANVWLQGVVKEHHSRN
>Mature_291_residues
MEEGLIDRLLETLWLDRRLNQNTLNGYRRDLEKIARRLSQSGRTLKDADEADLAAAVYVDGEQRSSQARALSACKRLYIW
MEREGIRTDNPTRLLKPPKIDKNIPTLITEQQISRLLATPDTDTPHGLRDKALLELMYATGLRVSEAVGLNFGNVDLDRG
CITALGKGDKQRMVPMGQESAYWVERYYTEARPLLLKGRNCDALFVSQKKTGISRQLAWMIVKEYAGRAGIGHISPHSLR
HAFATHLVQHGLDLRVVQDMLGHADLNTTQIYTHVANVWLQGVVKEHHSRN

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=290, Percent_Identity=48.2758620689655, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1790244, Length=290, Percent_Identity=35.8620689655172, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790768, Length=149, Percent_Identity=34.2281879194631, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790767, Length=183, Percent_Identity=30.6010928961749, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32972; Mature: 32972

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEGLIDRLLETLWLDRRLNQNTLNGYRRDLEKIARRLSQSGRTLKDADEADLAAAVYVD
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEEEC
GEQRSSQARALSACKRLYIWMEREGIRTDNPTRLLKPPKIDKNIPTLITEQQISRLLATP
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
DTDTPHGLRDKALLELMYATGLRVSEAVGLNFGNVDLDRGCITALGKGDKQRMVPMGQES
CCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCH
AYWVERYYTEARPLLLKGRNCDALFVSQKKTGISRQLAWMIVKEYAGRAGIGHISPHSLR
HHHHHHHHHHCCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
HAFATHLVQHGLDLRVVQDMLGHADLNTTQIYTHVANVWLQGVVKEHHSRN
HHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEEGLIDRLLETLWLDRRLNQNTLNGYRRDLEKIARRLSQSGRTLKDADEADLAAAVYVD
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEEEC
GEQRSSQARALSACKRLYIWMEREGIRTDNPTRLLKPPKIDKNIPTLITEQQISRLLATP
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
DTDTPHGLRDKALLELMYATGLRVSEAVGLNFGNVDLDRGCITALGKGDKQRMVPMGQES
CCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCH
AYWVERYYTEARPLLLKGRNCDALFVSQKKTGISRQLAWMIVKEYAGRAGIGHISPHSLR
HHHHHHHHHHCCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
HAFATHLVQHGLDLRVVQDMLGHADLNTTQIYTHVANVWLQGVVKEHHSRN
HHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]