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The map label for this gene is ubiA [H]

Identifier: 161869677

GI number: 161869677

Start: 706176

End: 707066

Strand: Direct

Name: ubiA [H]

Synonym: NMCC_0695

Alternate gene names: 161869677

Gene position: 706176-707066 (Clockwise)

Preceding gene: 161869676

Following gene: 161869678

Centisome position: 32.79

GC content: 52.64

Gene sequence:

>891_bases
ATGAATCCTAAATCCCCTTTATTTTTACGACTGTCCGACCGTTTGGATGTGTACCTGCGCCTGATGCGGGCGGACAAGCC
CATTGGGACGCTGCTTTTACTGTGGCCGACCTACTGGGCATTGTGGCTGGCTTCAGACGGCATTCCCGATTTGGCGGTAT
TGGCGGCGTTTACAATCGGTACGTTTTTAATGCGCAGTGCCGGCTGCGTCATCAACGATTTTGCCGACCGCGATTTTGAC
GGGGCTGTCGAGCGCACTAAAAACCGTCCGTTCGCACAGGGCAGGGTCAAGAAAAAAGAAGCGCTGCTGCTGACGGCATT
TTTGTGCCTGCTTGCCGCATTGTGCCTGATTCCGCTGAATCATCTGACTTGGCTGATGAGCCTGCCCGCGCTGTTTCTTG
CGCTGACTTACCCGTTTACCAAACGTTTTTTTCCGATTCCCCAACTCTATCTCGGGCTTGCCTTTTCCTTCGGTATCCCG
ATGGCGTTTGCCGCAGTGGGCAACAGCGTCCCCGTTGAAGCATGGATACTTTTTACCGCCAATGTTTTATGGACACTGGC
TTACGACACTGTTTACGCCATGGCGGACAAAGAAGACGATTTGAAAATCGGCATCAAAACCTCCGCCGTCACATTCGGGC
GTTACGACATCGCCGCTGTTATGCTGTGTCATGGCGGCTTTACCCTGCTGATGGCAGTATTGGGTGCGGTTATCGGCGCG
GCTTGGGCATATTGGACGGCAATCCCCATCGTCCTGCTGCTGCAATACCGCCAATATGCCGCCATCAAAAGCCGCGTCCG
GCAAATCTGTTTTGAAACGTTTTTGGCAAACAACAGAATTGGTTGGGTGTGGTTTACCGCCATTTTTGCCCATACGTTTT
TCGCGAAATAA

Upstream 100 bases:

>100_bases
TTTCCCGTCACGGCGAGGAAATGCTGCTGACCGAGTATTTTCTGCCCGAACTGAAACGCTTTATCGGATAAAATACCGTT
TTTTCAAGCTGTGCGGCAAT

Downstream 100 bases:

>100_bases
GGCAGGGCAATGCCGTCTGAAGAGCCGTAAACTGCTTTGGACGGCATTTCTATCTGTGCCGAAAAGCGTTAAAATATGTT
TTTAAAACGCTGTGTTATGT

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLASDGIPDLAVLAAFTIGTFLMRSAGCVINDFADRDFD
GAVERTKNRPFAQGRVKKKEALLLTAFLCLLAALCLIPLNHLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIP
MAFAAVGNSVPVEAWILFTANVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIAAVMLCHGGFTLLMAVLGAVIGA
AWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLANNRIGWVWFTAIFAHTFFAK

Sequences:

>Translated_296_residues
MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLASDGIPDLAVLAAFTIGTFLMRSAGCVINDFADRDFD
GAVERTKNRPFAQGRVKKKEALLLTAFLCLLAALCLIPLNHLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIP
MAFAAVGNSVPVEAWILFTANVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIAAVMLCHGGFTLLMAVLGAVIGA
AWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLANNRIGWVWFTAIFAHTFFAK
>Mature_296_residues
MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLASDGIPDLAVLAAFTIGTFLMRSAGCVINDFADRDFD
GAVERTKNRPFAQGRVKKKEALLLTAFLCLLAALCLIPLNHLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIP
MAFAAVGNSVPVEAWILFTANVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIAAVMLCHGGFTLLMAVLGAVIGA
AWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLANNRIGWVWFTAIFAHTFFAK

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=281, Percent_Identity=36.2989323843416, Blast_Score=161, Evalue=6e-40,
Organism=Escherichia coli, GI1790473, Length=277, Percent_Identity=49.8194945848375, Blast_Score=268, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17553718, Length=288, Percent_Identity=36.4583333333333, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32565247, Length=287, Percent_Identity=35.5400696864112, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17553720, Length=183, Percent_Identity=42.0765027322404, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=46.0992907801418, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=45.7142857142857, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324370, Length=304, Percent_Identity=32.5657894736842, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21355567, Length=286, Percent_Identity=37.7622377622378, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 33200; Mature: 33200

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLASDGIPDLAVLAAFTIG
CCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TFLMRSAGCVINDFADRDFDGAVERTKNRPFAQGRVKKKEALLLTAFLCLLAALCLIPLN
HHHHHHCCCEEECCCCCCCCHHHHHHCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
HLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIPMAFAAVGNSVPVEAWILFTA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHH
NVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIAAVMLCHGGFTLLMAVLGAVIGA
HHHHHHHHHHHHHHCCCCCCEEEEEEECEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHH
AWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLANNRIGWVWFTAIFAHTFFAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLASDGIPDLAVLAAFTIG
CCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TFLMRSAGCVINDFADRDFDGAVERTKNRPFAQGRVKKKEALLLTAFLCLLAALCLIPLN
HHHHHHCCCEEECCCCCCCCHHHHHHCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
HLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIPMAFAAVGNSVPVEAWILFTA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHH
NVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIAAVMLCHGGFTLLMAVLGAVIGA
HHHHHHHHHHHHHHCCCCCCEEEEEEECEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHH
AWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLANNRIGWVWFTAIFAHTFFAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA