Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 161869663

GI number: 161869663

Start: 694886

End: 695296

Strand: Direct

Name: infC [H]

Synonym: NMCC_0681

Alternate gene names: 161869663

Gene position: 694886-695296 (Clockwise)

Preceding gene: 161869662

Following gene: 161869664

Centisome position: 32.27

GC content: 47.93

Gene sequence:

>411_bases
TTGGCTATGGCCGAAGGGCAGGATGTCGATTTGGTAGAGATTTCCCCAACTGCTAAACCGCCTGTGTGCAAACTGATGGA
TTACGGTAAATACAAATACCAGCAGGCCAAGAAACGCGACGAAGCCAAGAAAAACCAAAAGCAGGTGCAAATCAAGGAAA
TCAAATTCCGTCCGGGTACGGATGAGGGCGATTATCAAATCAAGATGCGCAACATTAACCGCTTCCTTGCCGACGGCGAT
AAAGTCAAAGTGACATTGCGTTTCCGCGGCCGTGAAATGGCTCACCAGCAACTCGGCGCGCAACTTTTGGAACGTGTAAA
AGAAGATTTGGCTGAAGTGGCGCAAATCGAGTCCTTTCCCAAAATGGAAGGTCGCCAAATGGTGATGATGATTGCGCCGA
AGAAAAAATAA

Upstream 100 bases:

>100_bases
AGAACGCGAAGCACGAATCAACGGCGAAATTACCGCCAAAGAAGTGCGTTTAATCAGTGAGTCAGGCGAACAGCTTGGTG
TCGTTTCAGTTCGTGAAGCT

Downstream 100 bases:

>100_bases
AGCTATAATTCTCCGCTTACTCCGATTGCCGCTTCGGAGTAAGTTTTTAATTGCGGCAAAAAACCGTGGCATTGTGGGTT
CAAGTGTTTGAAACCGATGT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MAMAEGQDVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGTDEGDYQIKMRNINRFLADGD
KVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFPKMEGRQMVMMIAPKKK

Sequences:

>Translated_136_residues
MAMAEGQDVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGTDEGDYQIKMRNINRFLADGD
KVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFPKMEGRQMVMMIAPKKK
>Mature_135_residues
AMAEGQDVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGTDEGDYQIKMRNINRFLADGDK
VKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFPKMEGRQMVMMIAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=134, Percent_Identity=67.1641791044776, Blast_Score=181, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 15746; Mature: 15614

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMAEGQDVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGT
CCCCCCCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCC
DEGDYQIKMRNINRFLADGDKVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFP
CCCCEEEEEECHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KMEGRQMVMMIAPKKK
CCCCCEEEEEEECCCC
>Mature Secondary Structure 
AMAEGQDVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGT
CCCCCCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCC
DEGDYQIKMRNINRFLADGDKVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFP
CCCCEEEEEECHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KMEGRQMVMMIAPKKK
CCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA