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The map label for this gene is lnt [H]

Identifier: 161869655

GI number: 161869655

Start: 685924

End: 687498

Strand: Reverse

Name: lnt [H]

Synonym: NMCC_0672

Alternate gene names: 161869655

Gene position: 687498-685924 (Counterclockwise)

Preceding gene: 161869656

Following gene: 161869654

Centisome position: 31.93

GC content: 55.94

Gene sequence:

>1575_bases
ATGTTCAGACGGTATCTTCCGAACAGACAGATGAATATGGTTTCCAAACTGGACAAATACTGGCAGCACCCCGCCCTCTA
CTGGCCTTTGCTCATCCTTTTTGCCGCCGCCACCCCCTTTACCTTCGCACCCTACTACCACTTTTGGCTGATGCCCTTGA
TTTTCGGTGCCTTCGTCCGCCTCATCGAACTGCGTCCGCGTTTTGCTGTCTCTTCCGCCTACCTGTTCGGCCTGACCGCA
TACACGACACAGTTCTACTGGATACACACCGCCCTGCACGACGTTTCCGGCCTGCCCGACCTCTATGCCGTACCGCTGAC
CTTCCTACTCCCCGCCTACCTTGCCCTTTATCCGGCACTGTGTTTCTGGCTGTGGAAAAAATTTACCCTGCCTCGGGGCA
TAAAAATCGGTTTGGTACTGCCCATCCTGTGGACGCTGACCGAGTTTGCCCGCGAACGTTTCCTGACCGGATTCGGCTGG
GGCGCAATCGGCTACTCCCAAATCACCCCGGACAGCCCGCTCGCCGGCTTTGCCCCATTGGGCGGCATCCACATGGTTAC
ACTGGCAACCGCCTTTCTCGGTGTCTGGCTGGTTTTGGCGAGTGATAACACCGCACGTTCGGGCAAACGCCTGCTTCCAA
TTATCCTGATTGCCGCCCTGCTTGCCGCAGGCTACACCGCCCGACAAACCGACTTCACCCGCCCCGACGGCAGCCGCAGC
ACCGTCGCCCTGCTTCAAGGCAACATCGACCAAACCCTCAAATGGCGTGAAGACCAAGTCATCCCGACCATACAGAAATA
TTACGAACAGGTCGGCAAAACCACTGCCGACATCGTCATCCTGCCCGAAACCGCCATCCCCGTTATGCGCCAAAACCTGC
CGGAAAACATACTGGCAAAATTTGCCGAACAGGCGCAAAACAACGGCAGCGCGCTCGCCGTCGGCATCAGCCAATACACT
TCGGACGGCAACGGTTACGAAAACGCCGTCATCAACCTGACCGGTTATCAGGAAAACAATCAGGACGGCATCCCCTACTA
CGCCAAAAACCACCTCGTCCCCTTCGGCGAATACAAACCGCTGCCCTTCCTGACCACGCCGCTTTACAAAATGATGAATA
TGCCCCTTTCCGACTTCCGCAAAGGCGGCGGTAAGCAATCCGCCCTGCTGATGAAAAACCAAAAAATCGCCTTCAACATC
TGTTACGAAGACGGATTCGGCGACGAACTGATTGCCGCCGCCAAAGATGCCACCCTGCTTGCCAATGCCAGCAATATGGC
GTGGTACGGAAAATCCAACGCCATGTACCAGCACCTCCAACAATCGCAGGCGCGGGCTATGGAACTCGGACGCTATATGG
TCCGCGCCACCAACACCGGCGCAACCGCCATCATCTCCCCCAAAGGCAACATCATCGCCCAAGCCCAACCCGATACGGAA
ACCGTATTGGAAGGACACATCAAAGGCTATGTCGGCGAAACGCCCTATATGAAAACCGGCAGTTCATGGTGGTTGATGGG
CATATTGGCCCTAGCCGCACTGATTCTTTTCATCTTCCGAAACAAAGAACACTGA

Upstream 100 bases:

>100_bases
GGCTGCTTTCCGGTTCGATTGCCTGCGCCCCCGCCTTGCCGCTGATGAATCGTTTCGGCAGGCATTGATTTCTTTTTCAA
ATACCGATGCCGTTTGAAAG

Downstream 100 bases:

>100_bases
TACCTGCACAGCCCGTCCGGACGGGCTGTCTTTTTTCAAAACGGCTATTTACATACAACCACGTATGTAATATAATTCCA
AAATCGAATTGAGCCATCAG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MFRRYLPNRQMNMVSKLDKYWQHPALYWPLLILFAAATPFTFAPYYHFWLMPLIFGAFVRLIELRPRFAVSSAYLFGLTA
YTTQFYWIHTALHDVSGLPDLYAVPLTFLLPAYLALYPALCFWLWKKFTLPRGIKIGLVLPILWTLTEFARERFLTGFGW
GAIGYSQITPDSPLAGFAPLGGIHMVTLATAFLGVWLVLASDNTARSGKRLLPIILIAALLAAGYTARQTDFTRPDGSRS
TVALLQGNIDQTLKWREDQVIPTIQKYYEQVGKTTADIVILPETAIPVMRQNLPENILAKFAEQAQNNGSALAVGISQYT
SDGNGYENAVINLTGYQENNQDGIPYYAKNHLVPFGEYKPLPFLTTPLYKMMNMPLSDFRKGGGKQSALLMKNQKIAFNI
CYEDGFGDELIAAAKDATLLANASNMAWYGKSNAMYQHLQQSQARAMELGRYMVRATNTGATAIISPKGNIIAQAQPDTE
TVLEGHIKGYVGETPYMKTGSSWWLMGILALAALILFIFRNKEH

Sequences:

>Translated_524_residues
MFRRYLPNRQMNMVSKLDKYWQHPALYWPLLILFAAATPFTFAPYYHFWLMPLIFGAFVRLIELRPRFAVSSAYLFGLTA
YTTQFYWIHTALHDVSGLPDLYAVPLTFLLPAYLALYPALCFWLWKKFTLPRGIKIGLVLPILWTLTEFARERFLTGFGW
GAIGYSQITPDSPLAGFAPLGGIHMVTLATAFLGVWLVLASDNTARSGKRLLPIILIAALLAAGYTARQTDFTRPDGSRS
TVALLQGNIDQTLKWREDQVIPTIQKYYEQVGKTTADIVILPETAIPVMRQNLPENILAKFAEQAQNNGSALAVGISQYT
SDGNGYENAVINLTGYQENNQDGIPYYAKNHLVPFGEYKPLPFLTTPLYKMMNMPLSDFRKGGGKQSALLMKNQKIAFNI
CYEDGFGDELIAAAKDATLLANASNMAWYGKSNAMYQHLQQSQARAMELGRYMVRATNTGATAIISPKGNIIAQAQPDTE
TVLEGHIKGYVGETPYMKTGSSWWLMGILALAALILFIFRNKEH
>Mature_524_residues
MFRRYLPNRQMNMVSKLDKYWQHPALYWPLLILFAAATPFTFAPYYHFWLMPLIFGAFVRLIELRPRFAVSSAYLFGLTA
YTTQFYWIHTALHDVSGLPDLYAVPLTFLLPAYLALYPALCFWLWKKFTLPRGIKIGLVLPILWTLTEFARERFLTGFGW
GAIGYSQITPDSPLAGFAPLGGIHMVTLATAFLGVWLVLASDNTARSGKRLLPIILIAALLAAGYTARQTDFTRPDGSRS
TVALLQGNIDQTLKWREDQVIPTIQKYYEQVGKTTADIVILPETAIPVMRQNLPENILAKFAEQAQNNGSALAVGISQYT
SDGNGYENAVINLTGYQENNQDGIPYYAKNHLVPFGEYKPLPFLTTPLYKMMNMPLSDFRKGGGKQSALLMKNQKIAFNI
CYEDGFGDELIAAAKDATLLANASNMAWYGKSNAMYQHLQQSQARAMELGRYMVRATNTGATAIISPKGNIIAQAQPDTE
TVLEGHIKGYVGETPYMKTGSSWWLMGILALAALILFIFRNKEH

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=511, Percent_Identity=31.1154598825832, Blast_Score=222, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 58671; Mature: 58671

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]