Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 161869613

GI number: 161869613

Start: 644954

End: 645715

Strand: Direct

Name: kdsB [H]

Synonym: NMCC_0629

Alternate gene names: 161869613

Gene position: 644954-645715 (Clockwise)

Preceding gene: 161869612

Following gene: 161869614

Centisome position: 29.95

GC content: 59.32

Gene sequence:

>762_bases
ATGACCGAATTCGTCGTATTGATTCCGGCGCGGCTGGATTCGTCGCGCCTGCCCGGAAAAGCCTTGGCGGACATCCACGG
CAAACCGATGGTCGTGCGCGTTGCCGAACAGGCGGCAAAAAGTAAAGCCGCGCGCGTCGTCGTCGCCACCGACCATCCCG
ATATTCAGACGGTCTGTCAGGCGCACGGCATCGAAGCGGTTATGACTTCAAACCGGCACGAAAGCGGCACGACGCGCCTT
GCCGAAGCCTCTGCCGCGCTGAAGCTGCCGCCGCATTTGATTGTTGTGAACGTACAGGGTGACGAGCCGCTGATTGCCCC
CGAACTCATCGACCGCACCGCCGAAGTACTCGTCGAAAACAACGTCCAAATGGCGACCGCCGCCCACGAATTGCACGATT
TCGACGAATTGATGAATCCCAATGCCGTCAAAGTCGTCCTCGACAAAAACCGCAACGCCATCTACTTCAGCCGCGCCCCG
ATTCCCTATCTGCGCGATGCAATGCGTGCCGGAAAACGCGAAATGCCGTCTGAAACCGCCGTCCTGCGACATATCGGCAT
CTACGCTTACCGCGCCGGCTTCCTGCAACGCTATGCCGAAATGAGCGTTTCGCCGCTGGAAACCATCGAATCGCTGGAAC
AGCTGCGCGTCCTGTGGCACGGTTATCCCATTGCCGTCGAAACCGCCAAAGAAGCCCCCGCCGCCGGTGTGGATACGCAA
GAGGACTTGGACAGGGTTCGCGCCGTATTTCAGACCGTATAA

Upstream 100 bases:

>100_bases
TGTGGAGCCGTCAGGCGAAGCTGGCGTATCCGATTAAAGACGGCATCCCCTATATGCTGGAAAACGAAGCGCGAGCGTTG
GGCGAAGAGGAGCTCAAAGT

Downstream 100 bases:

>100_bases
AACAGGTTCAAAGGGAAAAGATATGCAGCAACATATTGAAAAGTGGCAACACTTGAGCCGGGAAGAACAGAAAATCCTTG
CTGAAGTATGGGGTCTCGTG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTVCQAHGIEAVMTSNRHESGTTRL
AEASAALKLPPHLIVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAP
IPYLRDAMRAGKREMPSETAVLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQ
EDLDRVRAVFQTV

Sequences:

>Translated_253_residues
MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTVCQAHGIEAVMTSNRHESGTTRL
AEASAALKLPPHLIVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAP
IPYLRDAMRAGKREMPSETAVLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQ
EDLDRVRAVFQTV
>Mature_252_residues
TEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTVCQAHGIEAVMTSNRHESGTTRLA
EASAALKLPPHLIVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAPI
PYLRDAMRAGKREMPSETAVLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQE
DLDRVRAVFQTV

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=245, Percent_Identity=53.0612244897959, Blast_Score=247, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27840; Mature: 27709

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTVCQ
CCCEEEEEECCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHCEEEEECCCCCHHHHHH
AHGIEAVMTSNRHESGTTRLAEASAALKLPPHLIVVNVQGDEPLIAPELIDRTAEVLVEN
HCCCCEEEECCCCCCCCHHHHHHHHHEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
NVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAPIPYLRDAMRAGKREMPSETA
CCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHCHHCCCHHHH
VLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQ
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCH
EDLDRVRAVFQTV
HHHHHHHHHHHCC
>Mature Secondary Structure 
TEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTVCQ
CCEEEEEECCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHCEEEEECCCCCHHHHHH
AHGIEAVMTSNRHESGTTRLAEASAALKLPPHLIVVNVQGDEPLIAPELIDRTAEVLVEN
HCCCCEEEECCCCCCCCHHHHHHHHHEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
NVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAPIPYLRDAMRAGKREMPSETA
CCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHCHHCCCHHHH
VLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQ
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCH
EDLDRVRAVFQTV
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA