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The map label for this gene is yggW [H]

Identifier: 161869602

GI number: 161869602

Start: 633275

End: 634474

Strand: Reverse

Name: yggW [H]

Synonym: NMCC_0618

Alternate gene names: 161869602

Gene position: 634474-633275 (Counterclockwise)

Preceding gene: 161869603

Following gene: 161869601

Centisome position: 29.46

GC content: 55.33

Gene sequence:

>1200_bases
TTGCCCACTTTTCCGAACCACACCATGCACACCATTTCCTTTCCAAACCGCACCCGACTCACCGCCCTGCCGCCCCTGTC
GCTTTACATCCACATCCCGTGGTGCATCAAAAAATGCCCGTATTGCGACTTCAATTCCCACAGCCTGAAAAACGGATTGC
CCGAAGCCGCCTATATCGACGCGCTGCTGACCGATTTGCAGCTTGAATTGCCCAATATTTGGGGCAGGCCGGTGGAAACG
ATCTTTTTCGGCGGCGGTACGCCCAGCCTGTTTCAGGCGGAATCGATTGACCGTTTGTTAAGCGGCGTGCGTTCGCTGTT
GCGCTTGCAGCCGGAAGCGGAAATTACCTTGGAAGCCAATCCGGGGACATTTGAAATCGAGAAGTTTCAAGGATTTAAAG
ACGCAGGCATCACGCGGCTTTCTATTGGTGTACAAAGCTTCAACGACGATATGCTCTCAAGGCTGGGGCGCGTCCACAAC
GGTAAAGAAGCCTTAACCGCCATAGCTACTGCCTTGAAATTATTTGATAAAATCAATATCGACTTGATGTACGCCCTGCC
GAACCAAACCGTTCGGACGGCATTGGATGACGTACAAACCGCCATCGCCACGGGCGCAACCCACATCAGCGCGTATCACC
TGACGATGGAACCGAACACGCCGTTCGGACACACGCCGCCGAAAGGTTTGCCGCAAGACGAAGCCGCCCTCGACATCGAA
GACGCGGTACACGGCGCGCTGGAAAGCGCGGGTTTTGTCCACTACGAAACATCGGCTTTTGCGAAACCAGCCATGCAGTG
CCGCCACAATTTGAACTACTGGCAGTTCGGCGATTATTTAGGCATAGGCGCGGGCGCGCACGGCAAAATTTCCTATCCCG
ACCGCATCGAGCGCACCGTCCGCCGCCGCCACCCCAACGACTACCTCGCCTTAATGCAAAACCGACCGAGCGAAGCCGTC
GAACGCAAAACCGTCGCCGCCGAAGATTTGCCGTTTGAGTTCATGATGAACGCCCTGCGCCTGACCGACGGCGTACCCGC
CGCGATGTTGCAGGAACGCACGGGCGTACCGAGTGCCAAAATCATGGCGCAAATCGAAACAGCAAGGCAAAAAGGCCTGC
TGGAAACCGACCCTGCCGTATTCCGCCCGACCGAAAAAGGACGCTTGTTTTTAAACGATTTGCTGCAGTGTTTTTTATAG

Upstream 100 bases:

>100_bases
TGGAAAAAGCCAATGCCTTGGGCGTTTCCGTCCTCAGCGAAGCCGAACTGCTTACCCTGCTCGGCTGAACCCATGCCGTC
TGAACCGCCTTCAGACGGCA

Downstream 100 bases:

>100_bases
TGGATTAACAAAAACCAGTACGGCGTTGCCTCGCCTTAGCTCAAAGAGAACGATTCTCTAAGGTGCTGAAGCACCAAGTG
AATCGGTTCCGTACTATTTG

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPTFPNHTMHTISFPNRTRLTALPPLSLYIHIPWCIKKCPYCDFNSHSLKNGLPEAAYIDALLTDLQLELPNIWGRPVET
IFFGGGTPSLFQAESIDRLLSGVRSLLRLQPEAEITLEANPGTFEIEKFQGFKDAGITRLSIGVQSFNDDMLSRLGRVHN
GKEALTAIATALKLFDKINIDLMYALPNQTVRTALDDVQTAIATGATHISAYHLTMEPNTPFGHTPPKGLPQDEAALDIE
DAVHGALESAGFVHYETSAFAKPAMQCRHNLNYWQFGDYLGIGAGAHGKISYPDRIERTVRRRHPNDYLALMQNRPSEAV
ERKTVAAEDLPFEFMMNALRLTDGVPAAMLQERTGVPSAKIMAQIETARQKGLLETDPAVFRPTEKGRLFLNDLLQCFL

Sequences:

>Translated_399_residues
MPTFPNHTMHTISFPNRTRLTALPPLSLYIHIPWCIKKCPYCDFNSHSLKNGLPEAAYIDALLTDLQLELPNIWGRPVET
IFFGGGTPSLFQAESIDRLLSGVRSLLRLQPEAEITLEANPGTFEIEKFQGFKDAGITRLSIGVQSFNDDMLSRLGRVHN
GKEALTAIATALKLFDKINIDLMYALPNQTVRTALDDVQTAIATGATHISAYHLTMEPNTPFGHTPPKGLPQDEAALDIE
DAVHGALESAGFVHYETSAFAKPAMQCRHNLNYWQFGDYLGIGAGAHGKISYPDRIERTVRRRHPNDYLALMQNRPSEAV
ERKTVAAEDLPFEFMMNALRLTDGVPAAMLQERTGVPSAKIMAQIETARQKGLLETDPAVFRPTEKGRLFLNDLLQCFL
>Mature_398_residues
PTFPNHTMHTISFPNRTRLTALPPLSLYIHIPWCIKKCPYCDFNSHSLKNGLPEAAYIDALLTDLQLELPNIWGRPVETI
FFGGGTPSLFQAESIDRLLSGVRSLLRLQPEAEITLEANPGTFEIEKFQGFKDAGITRLSIGVQSFNDDMLSRLGRVHNG
KEALTAIATALKLFDKINIDLMYALPNQTVRTALDDVQTAIATGATHISAYHLTMEPNTPFGHTPPKGLPQDEAALDIED
AVHGALESAGFVHYETSAFAKPAMQCRHNLNYWQFGDYLGIGAGAHGKISYPDRIERTVRRRHPNDYLALMQNRPSEAVE
RKTVAAEDLPFEFMMNALRLTDGVPAAMLQERTGVPSAKIMAQIETARQKGLLETDPAVFRPTEKGRLFLNDLLQCFL

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=270, Percent_Identity=38.8888888888889, Blast_Score=182, Evalue=4e-46,
Organism=Escherichia coli, GI1789325, Length=382, Percent_Identity=49.738219895288, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI87082341, Length=393, Percent_Identity=24.4274809160305, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44369; Mature: 44238

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFPNHTMHTISFPNRTRLTALPPLSLYIHIPWCIKKCPYCDFNSHSLKNGLPEAAYID
CCCCCCCCEEEEECCCCCEEEECCCEEEEEECCHHHHHCCCCCCCCCHHHCCCCHHHHHH
ALLTDLQLELPNIWGRPVETIFFGGGTPSLFQAESIDRLLSGVRSLLRLQPEAEITLEAN
HHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
PGTFEIEKFQGFKDAGITRLSIGVQSFNDDMLSRLGRVHNGKEALTAIATALKLFDKINI
CCEEEEHHHCCCHHCCEEEEEECHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCE
DLMYALPNQTVRTALDDVQTAIATGATHISAYHLTMEPNTPFGHTPPKGLPQDEAALDIE
EEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHCCHH
DAVHGALESAGFVHYETSAFAKPAMQCRHNLNYWQFGDYLGIGAGAHGKISYPDRIERTV
HHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCEECCCEEEECCCCCCCCCCHHHHHHHH
RRRHPNDYLALMQNRPSEAVERKTVAAEDLPFEFMMNALRLTDGVPAAMLQERTGVPSAK
HHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCHHH
IMAQIETARQKGLLETDPAVFRPTEKGRLFLNDLLQCFL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure 
PTFPNHTMHTISFPNRTRLTALPPLSLYIHIPWCIKKCPYCDFNSHSLKNGLPEAAYID
CCCCCCCEEEEECCCCCEEEECCCEEEEEECCHHHHHCCCCCCCCCHHHCCCCHHHHHH
ALLTDLQLELPNIWGRPVETIFFGGGTPSLFQAESIDRLLSGVRSLLRLQPEAEITLEAN
HHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
PGTFEIEKFQGFKDAGITRLSIGVQSFNDDMLSRLGRVHNGKEALTAIATALKLFDKINI
CCEEEEHHHCCCHHCCEEEEEECHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCE
DLMYALPNQTVRTALDDVQTAIATGATHISAYHLTMEPNTPFGHTPPKGLPQDEAALDIE
EEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHCCHH
DAVHGALESAGFVHYETSAFAKPAMQCRHNLNYWQFGDYLGIGAGAHGKISYPDRIERTV
HHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCEECCCEEEECCCCCCCCCCHHHHHHHH
RRRHPNDYLALMQNRPSEAVERKTVAAEDLPFEFMMNALRLTDGVPAAMLQERTGVPSAK
HHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCHHH
IMAQIETARQKGLLETDPAVFRPTEKGRLFLNDLLQCFL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]