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The map label for this gene is ppa [H]

Identifier: 161869574

GI number: 161869574

Start: 612548

End: 613081

Strand: Reverse

Name: ppa [H]

Synonym: NMCC_0589

Alternate gene names: 161869574

Gene position: 613081-612548 (Counterclockwise)

Preceding gene: 161869575

Following gene: 161869573

Centisome position: 28.47

GC content: 52.43

Gene sequence:

>534_bases
ATGGCAGACTTCAACCAAATCCTGACCCCCGGCGACGTGGACGGCGGCATCATCAACGTTGTCAACGAAATCCCCGCCGG
CAGCAACCACAAAATCGAATGGAACCGCAAACTGGCCGCATTCCAACTCGACCGCGTCGAACCCGCCATCTTCGCCAAAC
CGACCAACTACGGCTTCATTCCCCAAACTTTGGACGAAGACGGCGACGAATTGGACGTGCTGCTCGTTACCGAACAACCT
TTGGCAACCGGCGTATTCTTGGAAGCGCGCGTTATCGGCGTGATGAAATTCGTTGACGACGGCGAAGTGGACGACAAAAT
CGTCTGCGTTCCTGCCGACGACCGCAACAACGGCAACGCCTACAAAACTTTGTCCGATTTGCCGCAACAGCTCATCAAAC
AAATCGAGTTCCACTTCAACCATTACAAAGACCTGAAAAAAGCAGGTACGACCAAAGTCGAATCGTGGGGCGATGCGGAA
GAAGCGAAAAAAGTCATCAAAGAATCCATCGAACGTTGGAACAAACAGGCATAA

Upstream 100 bases:

>100_bases
CACGCGCCCGTACACCCTTTCAGAGGCATCGGGCGCATTTTCAGCCGGACGTTTGTGCTATACTTTCAAACTTCACACTT
TCCCAAACAAAGGAAACCAA

Downstream 100 bases:

>100_bases
CGCCCGCCATGCCGTCTGAACGCCGTTTCAGACGGCATTTTTCCAAGCTCTAGGGAATACCGTCCCAATCGGCTATAATC
CGAACATACCGTTTCCGACC

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MADFNQILTPGDVDGGIINVVNEIPAGSNHKIEWNRKLAAFQLDRVEPAIFAKPTNYGFIPQTLDEDGDELDVLLVTEQP
LATGVFLEARVIGVMKFVDDGEVDDKIVCVPADDRNNGNAYKTLSDLPQQLIKQIEFHFNHYKDLKKAGTTKVESWGDAE
EAKKVIKESIERWNKQA

Sequences:

>Translated_177_residues
MADFNQILTPGDVDGGIINVVNEIPAGSNHKIEWNRKLAAFQLDRVEPAIFAKPTNYGFIPQTLDEDGDELDVLLVTEQP
LATGVFLEARVIGVMKFVDDGEVDDKIVCVPADDRNNGNAYKTLSDLPQQLIKQIEFHFNHYKDLKKAGTTKVESWGDAE
EAKKVIKESIERWNKQA
>Mature_176_residues
ADFNQILTPGDVDGGIINVVNEIPAGSNHKIEWNRKLAAFQLDRVEPAIFAKPTNYGFIPQTLDEDGDELDVLLVTEQPL
ATGVFLEARVIGVMKFVDDGEVDDKIVCVPADDRNNGNAYKTLSDLPQQLIKQIEFHFNHYKDLKKAGTTKVESWGDAEE
AKKVIKESIERWNKQA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=157, Percent_Identity=41.4012738853503, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19812; Mature: 19680

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFNQILTPGDVDGGIINVVNEIPAGSNHKIEWNRKLAAFQLDRVEPAIFAKPTNYGFI
CCCCHHCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEECCCCCCEEEECCCCCCCC
PQTLDEDGDELDVLLVTEQPLATGVFLEARVIGVMKFVDDGEVDDKIVCVPADDRNNGNA
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCH
YKTLSDLPQQLIKQIEFHFNHYKDLKKAGTTKVESWGDAEEAKKVIKESIERWNKQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADFNQILTPGDVDGGIINVVNEIPAGSNHKIEWNRKLAAFQLDRVEPAIFAKPTNYGFI
CCCHHCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEECCCCCCEEEECCCCCCCC
PQTLDEDGDELDVLLVTEQPLATGVFLEARVIGVMKFVDDGEVDDKIVCVPADDRNNGNA
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCH
YKTLSDLPQQLIKQIEFHFNHYKDLKKAGTTKVESWGDAEEAKKVIKESIERWNKQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]