BacMap

Definition	Neisseria meningitidis 053442, complete genome.
Accession	NC_010120
Length	2,153,416

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The map label for this gene is troB [H]

Identifier: 161869520

GI number: 161869520

Start: 559343

End: 560329

Strand: Reverse

Name: troB [H]

Synonym: NMCC_0534

Alternate gene names: 161869520

Gene position: 560329-559343 (Counterclockwise)

Preceding gene: 161869521

Following gene: 161869519

Centisome position: 26.02

GC content: 51.47

Gene sequence:

>987_bases
ATGCCGGCAAGTCAACGATATGCCTGCCCCTCATCCACCTTGATTAACAATCACTCCCGCCTATTCAAGCATAATTTACA
GACCAAACGTTATACAGTATCATATCAGCCATATAACGATAAACGCTTTACCGCCTTCCCTTTCAAAACCGCAAATCATC
ATGACACCTTCCCTTTTACTATCAGGATTGACTTTCCGCCTCATCCTTGCCCTGATTGCCGTATCCCTTTTATGGGGCGT
TTACTTTTGGGCAGTATCCGCATGAGCATCATTGTCGAAAACCTGACCGTCAGCTACCGCCGCCGACCTGCCGTGCACCA
TGTGGACATTACTTTTGAAGAACATAGTATGTGGGCGGTTTTCGGTCCCAACGGCGCAGGGAAATCCACCTTTCTCAAAT
CCTTAATGGGATTGCAGCCTATCGATACGGGCAGCATCCGGCTGGACGGATTGACCCGTCAGAACATTGCCTACCTTCCC
CAGCAGTCCGACATCGACCGCTCGCAGCCCATGACCGTTTTCGACTTGGCGGCAATGGGGCTATGGTATGAAATCGGTTT
TTTCAGAGGAATAAATGCCGTTCAAAAACAACGCGTTCACGAATCTTTGGAACGCGTCGGGATGCGGCAGTTTGCCGGCC
GCCAAATCGCCCACCTCTCAAACGGACAATTCCAGCGTGTCCTTTTTGCCCGAATGCTGGTTCAAAACGCCAAATTCCTA
CTTCTAGACGAACCTTTCAACGCTGTTGATGCACGGACGACCTACGAACTTCTCGACGTATTGCAGAAATGCCATTGCGG
CGGACACGCCATCATCGCCGTACTGCACGATTACGAACAAGTCCGTGCCTACTTTCCCAATACCCTGCTGCTCGCCCGCG
AAAAAATTGCGGCAGGCGCAACCGAGACCATTCTGACAGAACCCTACCTCGCCCAAGCCAACGCCAAAATGCAGCAACAG
GAAAGCCCCGAGTGGTGCGCCTCATAA

Upstream 100 bases:

>100_bases
AAGCTGCACGCATTAAAGAAAAATTGCCTGCACGCAAAGGTTAATAAGCGATTTCCCCCAATGCCGTCTGAACCTTCAGA
CGGCATTTCTTATTGCTGCG

Downstream 100 bases:

>100_bases
ATGCCGTCTGAAACCATGTCCCCGTACCAAACACTATGAACCCCTACGACCTGCTTATCACACCCTTTGCAGAATTCGAC
TTTATGCGCTACGCCCTCGC

Product: ABC-transporter ATP-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MPASQRYACPSSTLINNHSRLFKHNLQTKRYTVSYQPYNDKRFTAFPFKTANHHDTFPFTIRIDFPPHPCPDCRIPFMGR
LLLGSIRMSIIVENLTVSYRRRPAVHHVDITFEEHSMWAVFGPNGAGKSTFLKSLMGLQPIDTGSIRLDGLTRQNIAYLP
QQSDIDRSQPMTVFDLAAMGLWYEIGFFRGINAVQKQRVHESLERVGMRQFAGRQIAHLSNGQFQRVLFARMLVQNAKFL
LLDEPFNAVDARTTYELLDVLQKCHCGGHAIIAVLHDYEQVRAYFPNTLLLAREKIAAGATETILTEPYLAQANAKMQQQ
ESPEWCAS

Sequences:

>Translated_328_residues
MPASQRYACPSSTLINNHSRLFKHNLQTKRYTVSYQPYNDKRFTAFPFKTANHHDTFPFTIRIDFPPHPCPDCRIPFMGR
LLLGSIRMSIIVENLTVSYRRRPAVHHVDITFEEHSMWAVFGPNGAGKSTFLKSLMGLQPIDTGSIRLDGLTRQNIAYLP
QQSDIDRSQPMTVFDLAAMGLWYEIGFFRGINAVQKQRVHESLERVGMRQFAGRQIAHLSNGQFQRVLFARMLVQNAKFL
LLDEPFNAVDARTTYELLDVLQKCHCGGHAIIAVLHDYEQVRAYFPNTLLLAREKIAAGATETILTEPYLAQANAKMQQQ
ESPEWCAS
>Mature_327_residues
PASQRYACPSSTLINNHSRLFKHNLQTKRYTVSYQPYNDKRFTAFPFKTANHHDTFPFTIRIDFPPHPCPDCRIPFMGRL
LLGSIRMSIIVENLTVSYRRRPAVHHVDITFEEHSMWAVFGPNGAGKSTFLKSLMGLQPIDTGSIRLDGLTRQNIAYLPQ
QSDIDRSQPMTVFDLAAMGLWYEIGFFRGINAVQKQRVHESLERVGMRQFAGRQIAHLSNGQFQRVLFARMLVQNAKFLL
LDEPFNAVDARTTYELLDVLQKCHCGGHAIIAVLHDYEQVRAYFPNTLLLAREKIAAGATETILTEPYLAQANAKMQQQE
SPEWCAS

Specific function: Part of an ATP-driven transport system TroABCD for zinc [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955968, Length=204, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI9955966, Length=174, Percent_Identity=31.6091954022989, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI45243524, Length=174, Percent_Identity=31.6091954022989, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI171184400, Length=250, Percent_Identity=26.8, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI105990541, Length=261, Percent_Identity=27.2030651340996, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI9955970, Length=165, Percent_Identity=29.6969696969697, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI134142337, Length=167, Percent_Identity=31.7365269461078, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI134142335, Length=167, Percent_Identity=31.7365269461078, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21729876, Length=225, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21729873, Length=225, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI15149474, Length=225, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9961252, Length=208, Percent_Identity=27.8846153846154, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI4505771, Length=208, Percent_Identity=27.8846153846154, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI9961250, Length=208, Percent_Identity=27.8846153846154, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788165, Length=223, Percent_Identity=30.9417040358744, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786345, Length=225, Percent_Identity=31.5555555555556, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790739, Length=249, Percent_Identity=28.1124497991968, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081791, Length=227, Percent_Identity=33.920704845815, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786563, Length=202, Percent_Identity=33.1683168316832, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788761, Length=230, Percent_Identity=32.6086956521739, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1790544, Length=213, Percent_Identity=34.2723004694836, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789593, Length=226, Percent_Identity=26.9911504424779, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786253, Length=221, Percent_Identity=30.316742081448, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786803, Length=225, Percent_Identity=29.7777777777778, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787712, Length=194, Percent_Identity=30.4123711340206, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787370, Length=217, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787029, Length=225, Percent_Identity=25.7777777777778, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786872, Length=186, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787041, Length=212, Percent_Identity=30.6603773584906, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87081709, Length=179, Percent_Identity=30.1675977653631, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788225, Length=237, Percent_Identity=25.7383966244726, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786975, Length=173, Percent_Identity=29.4797687861272, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081782, Length=192, Percent_Identity=30.7291666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787164, Length=249, Percent_Identity=28.5140562248996, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788450, Length=215, Percent_Identity=29.3023255813954, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789032, Length=222, Percent_Identity=28.8288288288288, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081834, Length=192, Percent_Identity=30.7291666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789864, Length=254, Percent_Identity=27.9527559055118, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786398, Length=210, Percent_Identity=30, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786654, Length=181, Percent_Identity=30.3867403314917, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788002, Length=213, Percent_Identity=28.6384976525822, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787089, Length=240, Percent_Identity=23.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48995001, Length=231, Percent_Identity=22.0779220779221, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790467, Length=224, Percent_Identity=25.8928571428571, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787105, Length=171, Percent_Identity=30.4093567251462, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786653, Length=183, Percent_Identity=28.4153005464481, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789991, Length=241, Percent_Identity=23.6514522821577, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=26.2135922330097, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=209, Percent_Identity=29.1866028708134, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17569081, Length=172, Percent_Identity=31.3953488372093, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567265, Length=198, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=233, Percent_Identity=27.0386266094421, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566680, Length=165, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=214, Percent_Identity=27.5700934579439, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17567269, Length=228, Percent_Identity=26.7543859649123, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=211, Percent_Identity=27.4881516587678, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=190, Percent_Identity=27.8947368421053, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71996550, Length=194, Percent_Identity=26.8041237113402, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28574744, Length=218, Percent_Identity=28.4403669724771, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574533, Length=180, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI161076684, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581617, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581615, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI161076682, Length=199, Percent_Identity=26.6331658291457, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85724858, Length=193, Percent_Identity=25.3886010362694, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85724856, Length=193, Percent_Identity=25.3886010362694, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580547, Length=193, Percent_Identity=25.3886010362694, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580551, Length=193, Percent_Identity=25.3886010362694, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580549, Length=193, Percent_Identity=25.3886010362694, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580545, Length=193, Percent_Identity=25.3886010362694, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45552437, Length=224, Percent_Identity=26.3392857142857, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24585557, Length=224, Percent_Identity=26.3392857142857, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28574150, Length=177, Percent_Identity=27.683615819209, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI116007328, Length=177, Percent_Identity=27.683615819209, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28571209, Length=195, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 37432; Mature: 37301

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00589 PTS_HPR_SER ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASQRYACPSSTLINNHSRLFKHNLQTKRYTVSYQPYNDKRFTAFPFKTANHHDTFPFT
CCCCCCCCCCCCHHHCCHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCEEE
IRIDFPPHPCPDCRIPFMGRLLLGSIRMSIIVENLTVSYRRRPAVHHVDITFEEHSMWAV
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHCCCCEEEEEEEEECCCEEEE
FGPNGAGKSTFLKSLMGLQPIDTGSIRLDGLTRQNIAYLPQQSDIDRSQPMTVFDLAAMG
ECCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHH
LWYEIGFFRGINAVQKQRVHESLERVGMRQFAGRQIAHLSNGQFQRVLFARMLVQNAKFL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCEE
LLDEPFNAVDARTTYELLDVLQKCHCGGHAIIAVLHDYEQVRAYFPNTLLLAREKIAAGA
EEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHEEHHHHHHCCC
TETILTEPYLAQANAKMQQQESPEWCAS
CHHHHCCCHHHHCCCHHHHCCCCHHCCC
>Mature Secondary Structure 
PASQRYACPSSTLINNHSRLFKHNLQTKRYTVSYQPYNDKRFTAFPFKTANHHDTFPFT
CCCCCCCCCCCHHHCCHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCEEE
IRIDFPPHPCPDCRIPFMGRLLLGSIRMSIIVENLTVSYRRRPAVHHVDITFEEHSMWAV
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHCCCCEEEEEEEEECCCEEEE
FGPNGAGKSTFLKSLMGLQPIDTGSIRLDGLTRQNIAYLPQQSDIDRSQPMTVFDLAAMG
ECCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHH
LWYEIGFFRGINAVQKQRVHESLERVGMRQFAGRQIAHLSNGQFQRVLFARMLVQNAKFL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCEE
LLDEPFNAVDARTTYELLDVLQKCHCGGHAIIAVLHDYEQVRAYFPNTLLLAREKIAAGA
EEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHEEHHHHHHCCC
TETILTEPYLAQANAKMQQQESPEWCAS
CHHHHCCCHHHHCCCHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9332349; 9665876 [H]