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The map label for this gene is mntC [H]

Identifier: 161869518

GI number: 161869518

Start: 557441

End: 558355

Strand: Reverse

Name: mntC [H]

Synonym: NMCC_0532

Alternate gene names: 161869518

Gene position: 558355-557441 (Counterclockwise)

Preceding gene: 161869519

Following gene: 161869515

Centisome position: 25.93

GC content: 53.55

Gene sequence:

>915_bases
ATGAAACACCCCAAACTCACCCTTATCGCCGCATTGCTGACCACTGCCGCAACTGCCGCCCCCCTGCCAGTTGTAACCAG
CTTCAGCATTTTAGGCGACGTAGCCAAACAAATCGGCGGAGAGCGCGTATCCATACAAAGTTTGGTCGGAGCCAACCAAG
ATACGCACGCCTATCACATGACCAGTGGCGACATTAAAAAAATCCGCAGTGCAAAACTCGTCCTGCTCAACGGCTTAGGA
CTTGAAGCTGCCGATGTACAACGTGCCGTCAAACAGAGCAAAGTATCCTATGCCGAAGCGACCAAAGGCATCCAACCCCT
CAAAGCCGAAGAAGAAGGCGGACACCATCACGACCACGATCATGACCACGAAGGACACCACCATGACCACGGCGAATATG
ACCCCCACGTCTGGAACGACCCCGTCCTTATGTCCGCCTATGCCCAAAACGTTGCCGAAGCCCTGATAAAGGCCGATCCC
GAAGGCAAAGTTTATTATCAACAACGCTTGGGCAACTACCAAATGCAGCTCAAAAAACTGCACAGCGACGCACAAGCCGC
ATTTAATGCCGTCCCTGCTGCCAAACGCAAAGTCCTGACCGGGCACGATGCCTTTTCCTATATGGGCAAACGTTACCATA
TCGAATTCATCGCCCCGCAAGGCGTGAGCAGCGAAGCCGAGCCTTCGGCCAAACAAGTCGCCGCCATCATCCGCCAAATC
AAACGCGAAGGCATCAAAGCCGTATTTACCGAAAACATCAAAGACACCCGTATGGTTGACCGCATCGCCAAAGAAACCGG
CGTCAACGTCAGCGGCAAACTGTATTCCGACGCACTCGGCAACGCGCCCGCAGACACCTACATCGGAATGTACCGCCACA
ACATCAAAGCCTTGACCAACGCGATGAAGCAATAA

Upstream 100 bases:

>100_bases
AACCACCGCCACCACACCACCTGACCCCGCAAGCCGCTTGAACAAACAGGCGGCTTGTTTTACCATAACAGATGTTACGT
TATATCACAGGAGAACAATT

Downstream 100 bases:

>100_bases
AACCGTTTGATTGGTTTGAATTTGAAAAGGCAAAAGGCCGTCTGAAAATTATAGTGGATTAACAAAAATCAGGACAAGGC
GACAAAGCCGCAGACAGTAC

Product: putative periplasmic binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Pneumococcal surface adhesin A [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKHPKLTLIAALLTTAATAAPLPVVTSFSILGDVAKQIGGERVSIQSLVGANQDTHAYHMTSGDIKKIRSAKLVLLNGLG
LEAADVQRAVKQSKVSYAEATKGIQPLKAEEEGGHHHDHDHDHEGHHHDHGEYDPHVWNDPVLMSAYAQNVAEALIKADP
EGKVYYQQRLGNYQMQLKKLHSDAQAAFNAVPAAKRKVLTGHDAFSYMGKRYHIEFIAPQGVSSEAEPSAKQVAAIIRQI
KREGIKAVFTENIKDTRMVDRIAKETGVNVSGKLYSDALGNAPADTYIGMYRHNIKALTNAMKQ

Sequences:

>Translated_304_residues
MKHPKLTLIAALLTTAATAAPLPVVTSFSILGDVAKQIGGERVSIQSLVGANQDTHAYHMTSGDIKKIRSAKLVLLNGLG
LEAADVQRAVKQSKVSYAEATKGIQPLKAEEEGGHHHDHDHDHEGHHHDHGEYDPHVWNDPVLMSAYAQNVAEALIKADP
EGKVYYQQRLGNYQMQLKKLHSDAQAAFNAVPAAKRKVLTGHDAFSYMGKRYHIEFIAPQGVSSEAEPSAKQVAAIIRQI
KREGIKAVFTENIKDTRMVDRIAKETGVNVSGKLYSDALGNAPADTYIGMYRHNIKALTNAMKQ
>Mature_304_residues
MKHPKLTLIAALLTTAATAAPLPVVTSFSILGDVAKQIGGERVSIQSLVGANQDTHAYHMTSGDIKKIRSAKLVLLNGLG
LEAADVQRAVKQSKVSYAEATKGIQPLKAEEEGGHHHDHDHDHEGHHHDHGEYDPHVWNDPVLMSAYAQNVAEALIKADP
EGKVYYQQRLGNYQMQLKKLHSDAQAAFNAVPAAKRKVLTGHDAFSYMGKRYHIEFIAPQGVSSEAEPSAKQVAAIIRQI
KREGIKAVFTENIKDTRMVDRIAKETGVNVSGKLYSDALGNAPADTYIGMYRHNIKALTNAMKQ

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=274, Percent_Identity=24.8175182481752, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33250; Mature: 33250

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHPKLTLIAALLTTAATAAPLPVVTSFSILGDVAKQIGGERVSIQSLVGANQDTHAYHM
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCEEEE
TSGDIKKIRSAKLVLLNGLGLEAADVQRAVKQSKVSYAEATKGIQPLKAEEEGGHHHDHD
CCCHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
HDHEGHHHDHGEYDPHVWNDPVLMSAYAQNVAEALIKADPEGKVYYQQRLGNYQMQLKKL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHH
HSDAQAAFNAVPAAKRKVLTGHDAFSYMGKRYHIEFIAPQGVSSEAEPSAKQVAAIIRQI
HHHHHHHHHHCCHHHHHHHCCCHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
KREGIKAVFTENIKDTRMVDRIAKETGVNVSGKLYSDALGNAPADTYIGMYRHNIKALTN
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
AMKQ
HHCC
>Mature Secondary Structure
MKHPKLTLIAALLTTAATAAPLPVVTSFSILGDVAKQIGGERVSIQSLVGANQDTHAYHM
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCEEEE
TSGDIKKIRSAKLVLLNGLGLEAADVQRAVKQSKVSYAEATKGIQPLKAEEEGGHHHDHD
CCCHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
HDHEGHHHDHGEYDPHVWNDPVLMSAYAQNVAEALIKADPEGKVYYQQRLGNYQMQLKKL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHH
HSDAQAAFNAVPAAKRKVLTGHDAFSYMGKRYHIEFIAPQGVSSEAEPSAKQVAAIIRQI
HHHHHHHHHHCCHHHHHHHCCCHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
KREGIKAVFTENIKDTRMVDRIAKETGVNVSGKLYSDALGNAPADTYIGMYRHNIKALTN
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
AMKQ
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7505262 [H]