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The map label for this gene is dsbC [H]

Identifier: 161869480

GI number: 161869480

Start: 513094

End: 513918

Strand: Reverse

Name: dsbC [H]

Synonym: NMCC_0492

Alternate gene names: 161869480

Gene position: 513918-513094 (Counterclockwise)

Preceding gene: 161869482

Following gene: 161869477

Centisome position: 23.87

GC content: 54.67

Gene sequence:

>825_bases
TTGATACAATTCCGCTTTTCCAACACGCGCAATCATCTTTATATGAAAACCAAGTTAATCAAAATCTTGACCCCCTTTAC
CGTCCTCCCACTGCTGGCTTGCGGGCAAACGCCCGTTTCCAATGCCAACGCCGAACCCGCCGTCAAAGCCGAGTCCGCCG
GCAAATCCGTTGCCGCCTCTTTGAAAGCGCGTTTGGAAAAAACCTATTCCGCCCAAGATTTGAAAGTGTTGAGCGTCAGC
GAAACACCGGTCAAAGGCATTTACGAAGTCGTCGTCAGCGGCAGGCAGATTATCTACACCGATGCCGAAGGCGGCTATAT
GTTCGTCGGCGAACTCATCAACATCGACACGCGCAAAAACCTGACCGAAGAACGCGCCGCCGATTTGAACAAAATCGACT
TCGCCTCCCTGCCTTTGGACAAAGCCATCAAAGAAGTGCGCGGCAACGGCAAGCTGAAAGTCGCCGTCTTCTCCGACCCC
GATTGTCCGTTCTGCAAACGCTTGGAACACGAGTTTGAAAAAATGACCGACGTGACGGTTTACAGCTTTATGATGCCCAT
TGCCGGCCTGCACCCCGATGCCGCGCGCAAGGCGCAAATCTTATGGTGTCAGCCCGACCGCGCCAAAGCGTGGACGGATT
GGATGCGTAAAGGCAAATTCCCGGTCGGCGGCAGCATCTGCGACAATCCCGTCGCGGAAACCACTTCCTTGGGCGAACAA
TTCGGCTTCAACGGCACGCCGACCCTCGTCTTCCCCAACGGGCGCAGCCAAAGCGGCTACAGCCCGATGCCCCAACTGGA
GGAAATCATCCGCAAAAATCAATAA

Upstream 100 bases:

>100_bases
TCATACAGGCAGGCAAATCATTTTTTTGCGTATTTTAACAGGCGGAAGCTATTTTCAGACGATAAATTGAGCCTAGGCGC
AATGCAGGCGCAACAGAGAT

Downstream 100 bases:

>100_bases
TCCATCCGCAAAACAAAAGGCTTGGAAAATTCCAAGCCTTTTTTGCGGGAAATGCCGTCTGAAAACCAATCCGCACTGAA
AGTTAGTAAGCCAACAAACA

Product: thiol:disulphide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MIQFRFSNTRNHLYMKTKLIKILTPFTVLPLLACGQTPVSNANAEPAVKAESAGKSVAASLKARLEKTYSAQDLKVLSVS
ETPVKGIYEVVVSGRQIIYTDAEGGYMFVGELINIDTRKNLTEERAADLNKIDFASLPLDKAIKEVRGNGKLKVAVFSDP
DCPFCKRLEHEFEKMTDVTVYSFMMPIAGLHPDAARKAQILWCQPDRAKAWTDWMRKGKFPVGGSICDNPVAETTSLGEQ
FGFNGTPTLVFPNGRSQSGYSPMPQLEEIIRKNQ

Sequences:

>Translated_274_residues
MIQFRFSNTRNHLYMKTKLIKILTPFTVLPLLACGQTPVSNANAEPAVKAESAGKSVAASLKARLEKTYSAQDLKVLSVS
ETPVKGIYEVVVSGRQIIYTDAEGGYMFVGELINIDTRKNLTEERAADLNKIDFASLPLDKAIKEVRGNGKLKVAVFSDP
DCPFCKRLEHEFEKMTDVTVYSFMMPIAGLHPDAARKAQILWCQPDRAKAWTDWMRKGKFPVGGSICDNPVAETTSLGEQ
FGFNGTPTLVFPNGRSQSGYSPMPQLEEIIRKNQ
>Mature_274_residues
MIQFRFSNTRNHLYMKTKLIKILTPFTVLPLLACGQTPVSNANAEPAVKAESAGKSVAASLKARLEKTYSAQDLKVLSVS
ETPVKGIYEVVVSGRQIIYTDAEGGYMFVGELINIDTRKNLTEERAADLNKIDFASLPLDKAIKEVRGNGKLKVAVFSDP
DCPFCKRLEHEFEKMTDVTVYSFMMPIAGLHPDAARKAQILWCQPDRAKAWTDWMRKGKFPVGGSICDNPVAETTSLGEQ
FGFNGTPTLVFPNGRSQSGYSPMPQLEEIIRKNQ

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=224, Percent_Identity=26.7857142857143, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 30383; Mature: 30383

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQFRFSNTRNHLYMKTKLIKILTPFTVLPLLACGQTPVSNANAEPAVKAESAGKSVAAS
CEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHCCHHHHHH
LKARLEKTYSAQDLKVLSVSETPVKGIYEVVVSGRQIIYTDAEGGYMFVGELINIDTRKN
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCC
LTEERAADLNKIDFASLPLDKAIKEVRGNGKLKVAVFSDPDCPFCKRLEHEFEKMTDVTV
CHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
YSFMMPIAGLHPDAARKAQILWCQPDRAKAWTDWMRKGKFPVGGSICDNPVAETTSLGEQ
HHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
FGFNGTPTLVFPNGRSQSGYSPMPQLEEIIRKNQ
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MIQFRFSNTRNHLYMKTKLIKILTPFTVLPLLACGQTPVSNANAEPAVKAESAGKSVAAS
CEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHCCHHHHHH
LKARLEKTYSAQDLKVLSVSETPVKGIYEVVVSGRQIIYTDAEGGYMFVGELINIDTRKN
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCC
LTEERAADLNKIDFASLPLDKAIKEVRGNGKLKVAVFSDPDCPFCKRLEHEFEKMTDVTV
CHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
YSFMMPIAGLHPDAARKAQILWCQPDRAKAWTDWMRKGKFPVGGSICDNPVAETTSLGEQ
HHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
FGFNGTPTLVFPNGRSQSGYSPMPQLEEIIRKNQ
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA