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The map label for this gene is adhP [H]

Identifier: 161869476

GI number: 161869476

Start: 507556

End: 508602

Strand: Reverse

Name: adhP [H]

Synonym: NMCC_0488

Alternate gene names: 161869476

Gene position: 508602-507556 (Counterclockwise)

Preceding gene: 161869477

Following gene: 161869475

Centisome position: 23.62

GC content: 56.64

Gene sequence:

>1047_bases
ATGAAAATGCAGGCAGTTGTTGTGAATAAAAATGTAGCGGGCGATGTGGAAATAGTCGAACGCGAGGTTCGCCCGTTGGA
ATACGGCGAGGCGTTGGTCGAAGTCGAATATTGCGGCGTGTGCCACACCGACCTGCACGTTGCGGCAGGCGACTACGGCG
AAAAACCGGGCCGCGTGCTGGGACACGAGGGCATCGGTTTGGTTAAAGAAGTTGCCGACGGTGTGAAAAATCTGAAAGTC
GGCGACCGCGTCAGCATCGCCTGGCTGTTCCAAAGCTGCGGCTCGTGCGAATACTGCAATACCGGCCGCGAAACCCTGTG
CCGCTCTGTATTGAACGCGGGCTACACCGCCGACGGCGGTATGGCGACCCACTGCATCGTGAGTGCCGATTACGCGGTCA
AAGTCCCTGAAGGTTTGGATCCTGCGCAAGCTTCGAGCATTACTTGTGCCGGCGTGACCACTTATAAAGCCATTAAAGTT
TCCGGCGTTCGTCCGGGACAGTGGATTGCCATCTACGGCGCGGGCGGTTTGGGCAACTTGGGGGTCCAATACGCGAAAAA
AGTATTCGGCGCGCACGTTGTCGCCATCGACATCAACGACGACAAACTGGCGTTTGCCAAAGAAACCGGCGCGGATTTGG
TTGTCAACGCCGCCAAAGAGGACGCTGCCAAAGTGATTCAGGAAAAAACCGGCGGCGCACACGCTGCGGTCGTAACCGCC
GTATCTGCTGCCGCATTCAACTCTGCCGTGAATTGCGTCCGCGCGGGCGGACGTGTGGTTGCCATCGGGCTGCCGCCGGA
ATCGATGGATTTGTCCATCCCGCGTTTGGTTTTGGACGGCATCGAAGTGGTCGGCTCTTTGGTCGGCACGCGCAAAGATT
TGGAAGAAGCCTTCCAATTCGGCGCGGAAGGTTTGGTTGTGCCTAAAGTCGAGTTGCGTGCTTTGGATGAAGCGCCTGCC
ATCTTCCAAGAAATGCGCGAAGGTAAAATTACCGGCCGTATGGTGATTGATATGAAAAAAGAATGCGGCTGCGGCCATCA
CCACTGA

Upstream 100 bases:

>100_bases
ACATACCACTTGACCTGTGAGATGCGGAAGCGTATGCTTACCCTTATATCGGACAACATTCCGTTTACAGGTTTTTTTGC
CGTAACTAAGGAGCGCAATC

Downstream 100 bases:

>100_bases
TTTGACGTGGCGATACACATCGAAATGCCGTCTGAACGCTGTTCAGACGGCATTTTTTATGGATTTGGATTTGATTTTAA
TCTGTTCTGTTTGAAATACC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase I; ADH I [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKMQAVVVNKNVAGDVEIVEREVRPLEYGEALVEVEYCGVCHTDLHVAAGDYGEKPGRVLGHEGIGLVKEVADGVKNLKV
GDRVSIAWLFQSCGSCEYCNTGRETLCRSVLNAGYTADGGMATHCIVSADYAVKVPEGLDPAQASSITCAGVTTYKAIKV
SGVRPGQWIAIYGAGGLGNLGVQYAKKVFGAHVVAIDINDDKLAFAKETGADLVVNAAKEDAAKVIQEKTGGAHAAVVTA
VSAAAFNSAVNCVRAGGRVVAIGLPPESMDLSIPRLVLDGIEVVGSLVGTRKDLEEAFQFGAEGLVVPKVELRALDEAPA
IFQEMREGKITGRMVIDMKKECGCGHHH

Sequences:

>Translated_348_residues
MKMQAVVVNKNVAGDVEIVEREVRPLEYGEALVEVEYCGVCHTDLHVAAGDYGEKPGRVLGHEGIGLVKEVADGVKNLKV
GDRVSIAWLFQSCGSCEYCNTGRETLCRSVLNAGYTADGGMATHCIVSADYAVKVPEGLDPAQASSITCAGVTTYKAIKV
SGVRPGQWIAIYGAGGLGNLGVQYAKKVFGAHVVAIDINDDKLAFAKETGADLVVNAAKEDAAKVIQEKTGGAHAAVVTA
VSAAAFNSAVNCVRAGGRVVAIGLPPESMDLSIPRLVLDGIEVVGSLVGTRKDLEEAFQFGAEGLVVPKVELRALDEAPA
IFQEMREGKITGRMVIDMKKECGCGHHH
>Mature_348_residues
MKMQAVVVNKNVAGDVEIVEREVRPLEYGEALVEVEYCGVCHTDLHVAAGDYGEKPGRVLGHEGIGLVKEVADGVKNLKV
GDRVSIAWLFQSCGSCEYCNTGRETLCRSVLNAGYTADGGMATHCIVSADYAVKVPEGLDPAQASSITCAGVTTYKAIKV
SGVRPGQWIAIYGAGGLGNLGVQYAKKVFGAHVVAIDINDDKLAFAKETGADLVVNAAKEDAAKVIQEKTGGAHAAVVTA
VSAAAFNSAVNCVRAGGRVVAIGLPPESMDLSIPRLVLDGIEVVGSLVGTRKDLEEAFQFGAEGLVVPKVELRALDEAPA
IFQEMREGKITGRMVIDMKKECGCGHHH

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=339, Percent_Identity=30.9734513274336, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI34577061, Length=344, Percent_Identity=29.6511627906977, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI4501929, Length=339, Percent_Identity=30.3834808259587, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI262073058, Length=337, Percent_Identity=26.1127596439169, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI71743840, Length=337, Percent_Identity=26.1127596439169, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI71565154, Length=237, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI156627571, Length=260, Percent_Identity=29.2307692307692, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI71565152, Length=362, Percent_Identity=25.9668508287293, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI156523966, Length=352, Percent_Identity=26.7045454545455, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4501939, Length=352, Percent_Identity=26.7045454545455, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI28557745, Length=240, Percent_Identity=28.3333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081918, Length=337, Percent_Identity=69.7329376854599, Blast_Score=440, Evalue=1e-125,
Organism=Escherichia coli, GI1790045, Length=332, Percent_Identity=27.4096385542169, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787863, Length=275, Percent_Identity=30.1818181818182, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788073, Length=267, Percent_Identity=31.4606741573034, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786518, Length=358, Percent_Identity=28.4916201117318, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082401, Length=344, Percent_Identity=28.1976744186047, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI226510992, Length=298, Percent_Identity=27.8523489932886, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788075, Length=294, Percent_Identity=26.530612244898, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786552, Length=299, Percent_Identity=31.438127090301, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87082125, Length=339, Percent_Identity=25.3687315634218, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790718, Length=306, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786825, Length=244, Percent_Identity=27.4590163934426, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788407, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71988145, Length=342, Percent_Identity=35.672514619883, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17562584, Length=341, Percent_Identity=35.4838709677419, Blast_Score=190, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17562582, Length=341, Percent_Identity=35.4838709677419, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17562876, Length=254, Percent_Identity=31.496062992126, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17562878, Length=204, Percent_Identity=32.3529411764706, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25146526, Length=257, Percent_Identity=28.0155642023346, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71997431, Length=259, Percent_Identity=27.7992277992278, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565904, Length=253, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=345, Percent_Identity=38.5507246376812, Blast_Score=219, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6323961, Length=345, Percent_Identity=38.5507246376812, Blast_Score=218, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6319621, Length=343, Percent_Identity=36.4431486880466, Blast_Score=215, Evalue=8e-57,
Organism=Saccharomyces cerevisiae, GI6323729, Length=345, Percent_Identity=38.5507246376812, Blast_Score=212, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6319949, Length=335, Percent_Identity=30.1492537313433, Blast_Score=125, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6323980, Length=324, Percent_Identity=27.7777777777778, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6322619, Length=325, Percent_Identity=29.8461538461538, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319955, Length=325, Percent_Identity=29.5384615384615, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320033, Length=338, Percent_Identity=29.2899408284024, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323099, Length=255, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319258, Length=314, Percent_Identity=24.5222929936306, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17137530, Length=227, Percent_Identity=27.7533039647577, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17737897, Length=223, Percent_Identity=27.8026905829596, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737895, Length=223, Percent_Identity=31.8385650224215, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36549; Mature: 36549

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMQAVVVNKNVAGDVEIVEREVRPLEYGEALVEVEYCGVCHTDLHVAAGDYGEKPGRVL
CCEEEEEEECCCCCCHHHHHHHCCCHHHCCEEEEEEECCEECCCCEEECCCCCCCCCCEE
GHEGIGLVKEVADGVKNLKVGDRVSIAWLFQSCGSCEYCNTGRETLCRSVLNAGYTADGG
CCCCCHHHHHHHHHHHCCCCCCCCHHEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC
MATHCIVSADYAVKVPEGLDPAQASSITCAGVTTYKAIKVSGVRPGQWIAIYGAGGLGNL
CEEEEEEECCEEEECCCCCCCCCCCCEEEECEEEEEEEEECCCCCCCEEEEEECCCCCHH
GVQYAKKVFGAHVVAIDINDDKLAFAKETGADLVVNAAKEDAAKVIQEKTGGAHAAVVTA
HHHHHHHHHCCEEEEEEECCCCEEEECCCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHH
VSAAAFNSAVNCVRAGGRVVAIGLPPESMDLSIPRLVLDGIEVVGSLVGTRKDLEEAFQF
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GAEGLVVPKVELRALDEAPAIFQEMREGKITGRMVIDMKKECGCGHHH
CCCCEEECCHHHHHCCCCHHHHHHHHCCCCCEEEEEEEHHHCCCCCCC
>Mature Secondary Structure
MKMQAVVVNKNVAGDVEIVEREVRPLEYGEALVEVEYCGVCHTDLHVAAGDYGEKPGRVL
CCEEEEEEECCCCCCHHHHHHHCCCHHHCCEEEEEEECCEECCCCEEECCCCCCCCCCEE
GHEGIGLVKEVADGVKNLKVGDRVSIAWLFQSCGSCEYCNTGRETLCRSVLNAGYTADGG
CCCCCHHHHHHHHHHHCCCCCCCCHHEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC
MATHCIVSADYAVKVPEGLDPAQASSITCAGVTTYKAIKVSGVRPGQWIAIYGAGGLGNL
CEEEEEEECCEEEECCCCCCCCCCCCEEEECEEEEEEEEECCCCCCCEEEEEECCCCCHH
GVQYAKKVFGAHVVAIDINDDKLAFAKETGADLVVNAAKEDAAKVIQEKTGGAHAAVVTA
HHHHHHHHHCCEEEEEEECCCCEEEECCCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHH
VSAAAFNSAVNCVRAGGRVVAIGLPPESMDLSIPRLVLDGIEVVGSLVGTRKDLEEAFQF
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GAEGLVVPKVELRALDEAPAIFQEMREGKITGRMVIDMKKECGCGHHH
CCCCEEECCHHHHHCCCCHHHHHHHHCCCCCEEEEEEEHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2185223; 8320209; 2935393 [H]