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The map label for this gene is aspC [H]

Identifier: 161869469

GI number: 161869469

Start: 498633

End: 499826

Strand: Reverse

Name: aspC [H]

Synonym: NMCC_0481

Alternate gene names: 161869469

Gene position: 499826-498633 (Counterclockwise)

Preceding gene: 161869470

Following gene: 161869467

Centisome position: 23.21

GC content: 53.43

Gene sequence:

>1194_bases
ATGTTCTTCAAGCACATCGAAGCCGCCCCCGCCGATCCGATTCTCGGTTTGGGCGAAGCGTTCAAAGCCGAAACCCGCCC
CGAAAAAGTCAACCTCGGCATCGGCGTTTATAAAGACGCATCCGGCGCGACACCCCTCGTCAAAGCCGTCAAAGAAGCCG
AAAAACGCCTGTTGGAAAGCGAAACCACCAAAAACTACCTCACCATCGACGGCGTTGCCGACTACAACGCGCAAACCCAA
ATCCTGCTGTTCGGCAAAGACCACGAAATCATCGCCAGCCGTCGCGCCAAAACAGCGCAAAGCCTCGGCGGTACGGGCGC
ATTGCGTATTGCGGCCGAGTTTGCCAAACGCCAGTTGAACGCGCAAACCATCTGGATTTCCAATCCGACTTGGCCCAACC
ACAACGCCATCGCCAAAGCGGTCGGTATCCAAGACAAACCTTATCGTTACTATGATGCCGCCAAACACGGTTTGGATTGG
GACGGCATGATTGAGGACTTGAGCCAAGCGCAAAAAGGCGACATCGTCCTGCTGCACGGCTGCTGCCACAATCCTACCGG
CATCGACCCTACGCCCGAACAATGGGAAACTCTGGCAAAACTTTCTGCCGAAAAAGGCTGGCTGCCGCTGTTTGACTTTG
CCTACCAAGGCTTCGGCAACGGTCTGGAAGAAGATGCCTACGGCTTGCGCGTGTTCTTGAAACACAATACAGAATTGCTG
ATTGCCAGCTCTTATTCCAAAAACTTCGGTATGTACAACGAGCGCGTCGGCGCGTTCACTTTGGTGGCCGAAGATGAAGC
AACCGCCGCCCGCGCCCACAGCCAAGTCAAAACCATCATCCGTACCTTGTATTCCAACCCGGCTTCACACGGCGCGAACA
CTATTGCGCTGGTGTTGGAAAATGATGATTTGAAAGCACAATGGATTGCCGAACTCGATGAAATGCGCGGCCGCATCAAA
GCCATGCGCCAAAAATTTGTCGAGTTGCTCAAAGCCAAAGGCGCAAGCCAAAACTTTGATTTCATTATCGAACAAAACGG
TATGTTCTCCTTCAGCGGCTTGACTCCCGAACAAGTCGACCGCCTGAAAAACGAGTTTGCCATTTATGCCGTCCGCTCCG
GCCGCATCAACGTCGCCGGCATTACCGACGACAACATCGATTATCTGTGCGAAAGCATCGTGAAAGTACTGTAA

Upstream 100 bases:

>100_bases
CCATATCGGGCAGGCGTGATTGCGTCTGTTTCCAGCCCGTGTAAAACAGCGTAAAATCGGCAAACCCGAATGACCTTCCG
TCCCCATCAAGGAGCAAGCT

Downstream 100 bases:

>100_bases
AAAGCACAGCCATATGAAAATGCCGTCCGAACCTTAACCAGTTCAGACGGCATCTGTTTTTTGTTAAAAAACAATAAACC
ATAACAATTTCAAACAAGCT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MFFKHIEAAPADPILGLGEAFKAETRPEKVNLGIGVYKDASGATPLVKAVKEAEKRLLESETTKNYLTIDGVADYNAQTQ
ILLFGKDHEIIASRRAKTAQSLGGTGALRIAAEFAKRQLNAQTIWISNPTWPNHNAIAKAVGIQDKPYRYYDAAKHGLDW
DGMIEDLSQAQKGDIVLLHGCCHNPTGIDPTPEQWETLAKLSAEKGWLPLFDFAYQGFGNGLEEDAYGLRVFLKHNTELL
IASSYSKNFGMYNERVGAFTLVAEDEATAARAHSQVKTIIRTLYSNPASHGANTIALVLENDDLKAQWIAELDEMRGRIK
AMRQKFVELLKAKGASQNFDFIIEQNGMFSFSGLTPEQVDRLKNEFAIYAVRSGRINVAGITDDNIDYLCESIVKVL

Sequences:

>Translated_397_residues
MFFKHIEAAPADPILGLGEAFKAETRPEKVNLGIGVYKDASGATPLVKAVKEAEKRLLESETTKNYLTIDGVADYNAQTQ
ILLFGKDHEIIASRRAKTAQSLGGTGALRIAAEFAKRQLNAQTIWISNPTWPNHNAIAKAVGIQDKPYRYYDAAKHGLDW
DGMIEDLSQAQKGDIVLLHGCCHNPTGIDPTPEQWETLAKLSAEKGWLPLFDFAYQGFGNGLEEDAYGLRVFLKHNTELL
IASSYSKNFGMYNERVGAFTLVAEDEATAARAHSQVKTIIRTLYSNPASHGANTIALVLENDDLKAQWIAELDEMRGRIK
AMRQKFVELLKAKGASQNFDFIIEQNGMFSFSGLTPEQVDRLKNEFAIYAVRSGRINVAGITDDNIDYLCESIVKVL
>Mature_397_residues
MFFKHIEAAPADPILGLGEAFKAETRPEKVNLGIGVYKDASGATPLVKAVKEAEKRLLESETTKNYLTIDGVADYNAQTQ
ILLFGKDHEIIASRRAKTAQSLGGTGALRIAAEFAKRQLNAQTIWISNPTWPNHNAIAKAVGIQDKPYRYYDAAKHGLDW
DGMIEDLSQAQKGDIVLLHGCCHNPTGIDPTPEQWETLAKLSAEKGWLPLFDFAYQGFGNGLEEDAYGLRVFLKHNTELL
IASSYSKNFGMYNERVGAFTLVAEDEATAARAHSQVKTIIRTLYSNPASHGANTIALVLENDDLKAQWIAELDEMRGRIK
AMRQKFVELLKAKGASQNFDFIIEQNGMFSFSGLTPEQVDRLKNEFAIYAVRSGRINVAGITDDNIDYLCESIVKVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=397, Percent_Identity=42.5692695214106, Blast_Score=359, Evalue=3e-99,
Organism=Homo sapiens, GI4504067, Length=397, Percent_Identity=41.8136020151133, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI117414139, Length=381, Percent_Identity=28.3464566929134, Blast_Score=153, Evalue=2e-37,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=61.3636363636364, Blast_Score=522, Evalue=1e-149,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=41.5617128463476, Blast_Score=349, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI71981858, Length=393, Percent_Identity=41.9847328244275, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25147133, Length=396, Percent_Identity=40.1515151515151, Blast_Score=348, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17569539, Length=395, Percent_Identity=36.4556962025316, Blast_Score=278, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17569537, Length=394, Percent_Identity=30.9644670050761, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI25147136, Length=212, Percent_Identity=38.6792452830189, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=31.5589353612167, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=37.6847290640394, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6322743, Length=429, Percent_Identity=34.4988344988345, Blast_Score=247, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24580970, Length=397, Percent_Identity=44.5843828715365, Blast_Score=353, Evalue=1e-97,
Organism=Drosophila melanogaster, GI24580972, Length=397, Percent_Identity=44.5843828715365, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=45.2442159383033, Blast_Score=348, Evalue=3e-96,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=39.746835443038, Blast_Score=311, Evalue=7e-85,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=38.9873417721519, Blast_Score=310, Evalue=1e-84,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43945; Mature: 43945

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFKHIEAAPADPILGLGEAFKAETRPEKVNLGIGVYKDASGATPLVKAVKEAEKRLLES
CCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECEEEEECCCCCCHHHHHHHHHHHHHHHH
ETTKNYLTIDGVADYNAQTQILLFGKDHEIIASRRAKTAQSLGGTGALRIAAEFAKRQLN
CCCCCEEEECCEECCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
AQTIWISNPTWPNHNAIAKAVGIQDKPYRYYDAAKHGLDWDGMIEDLSQAQKGDIVLLHG
CEEEEECCCCCCCCCHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEC
CCHNPTGIDPTPEQWETLAKLSAEKGWLPLFDFAYQGFGNGLEEDAYGLRVFLKHNTELL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEE
IASSYSKNFGMYNERVGAFTLVAEDEATAARAHSQVKTIIRTLYSNPASHGANTIALVLE
EEECCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
NDDLKAQWIAELDEMRGRIKAMRQKFVELLKAKGASQNFDFIIEQNGMFSFSGLTPEQVD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCHHHHH
RLKNEFAIYAVRSGRINVAGITDDNIDYLCESIVKVL
HHHCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MFFKHIEAAPADPILGLGEAFKAETRPEKVNLGIGVYKDASGATPLVKAVKEAEKRLLES
CCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECEEEEECCCCCCHHHHHHHHHHHHHHHH
ETTKNYLTIDGVADYNAQTQILLFGKDHEIIASRRAKTAQSLGGTGALRIAAEFAKRQLN
CCCCCEEEECCEECCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
AQTIWISNPTWPNHNAIAKAVGIQDKPYRYYDAAKHGLDWDGMIEDLSQAQKGDIVLLHG
CEEEEECCCCCCCCCHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEC
CCHNPTGIDPTPEQWETLAKLSAEKGWLPLFDFAYQGFGNGLEEDAYGLRVFLKHNTELL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEE
IASSYSKNFGMYNERVGAFTLVAEDEATAARAHSQVKTIIRTLYSNPASHGANTIALVLE
EEECCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
NDDLKAQWIAELDEMRGRIKAMRQKFVELLKAKGASQNFDFIIEQNGMFSFSGLTPEQVD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCHHHHH
RLKNEFAIYAVRSGRINVAGITDDNIDYLCESIVKVL
HHHCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]