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The map label for this gene is gluP [H]

Identifier: 161869463

GI number: 161869463

Start: 492753

End: 494033

Strand: Direct

Name: gluP [H]

Synonym: NMCC_0475

Alternate gene names: 161869463

Gene position: 492753-494033 (Clockwise)

Preceding gene: 161869462

Following gene: 161869464

Centisome position: 22.88

GC content: 52.3

Gene sequence:

>1281_bases
ATGTCAATTTCTATTTTCTTGAAACGGGTAATATTCCGACACCACGAAAGGCAAATCATGTCTGCGCAATCACAAAACAA
TCATACGTCCCCATTGGTCGTCTTGACCACGCTGTTCTTCATGATGGGTTTTATTACCTGCATGAACGACATCCTTATCC
CTCATTTGAAAGAAATTTTCGACCTGTCTTACGTTCAGGCGATGCTGATCCAATTCTGTTTCTTTACTGCCTATGCGGTG
ATGTCCATCCCGATGGGGGCTTTTGTCGGCAAAGTCGGCTACAAAAACGGCGTTATCGGCGGCTTTCTGCTGACGGCGGT
CGGATGCCTGCTGTTTTATCCTGCTGCGGGCAGCCATTCTTACGCGGTATTTTTGGGCGCGTTGTTTATTTTGGCTTCCG
GCGTAACGCTGCTTCAGGTCGCCGGTAATCCTTATGTTACCCTGCTGGCGAAACCCGGCAAGGAATCGGCAACACTGACG
CTGGTTCAGGCGTTTAACGCTTTGGGTACGACCATTGCGCCGCAAATCGGCGCGTTCCTGATTTTGGCGGACGCAACCCA
AACCGTCAGCAAGGCGGAACAGATTTCTTCCGTACAGATTCCCTATTTGGGACTGGCGGGGCTGCTGATTATCCTTGCCG
TTTTCGTGAAAATGATCCGGCTGCCCGACGCGCGCAAAATTGCCGCCGAGGAAAGCGCGCACAACCACGACGGCAAAACC
AGCGTATGGCAATACAAACATCTCGTGTTCGGTACGGCAGGCATTTTCTGCTATGTCGGCGCGGAGGTGTCTATCGGTTC
GTTGATGGTCAACGTATTGGGTTATCTGAAAGGGCTGGATCATGCTTCTGCCGCGCATTACCTGTCGTTCTATTGGGGCG
GCGCGATGGTCGGACGTTTCCTCGGTTCGGCGGTGATGGCGAAATTCGCGCCCAACCGTTATTTGGCGTTTAACGCATCG
GCTGCGGTCGTACTGCTTGCCGTCGCGATGGCGACGGGTAGCGGCAATGCGGATGTGGCGATGTGGTCGCTGCTTGCCAT
CGGTTTTTTCAACTCGATTATGTTCCCGACGATTTTCTCTTTGGCAACCAAAGGATTGGGAAAATTTACCAACGCGGCTT
CCGGTGTACTGTGTACCGCGATTGTCGGCGGTGCGGTCGTTCCTGTCGTGCAGGGCTGGGTGGCAGATACTTACACCCTG
ATGTCTTCGTTTGTCGTTTCCGTCATCTGTTATCTGTATATCGTGTTTTTTGCGGTGTACGGATATAGGGCGGACAAATA
A

Upstream 100 bases:

>100_bases
TTAATTTCTGCTGCTTGAATTTCAGATCGGCGCATTGCCTGCATCCGATAAAGTTTGCAAAATGTTCAAATATCAGTATG
ATTTGCATTGCCGTTAAGAA

Downstream 100 bases:

>100_bases
TCTTTTTCTTGAGAAATGCCGTCTGAACATCTTTCAGACGGCATTTTTGCGTACCGGTGTTTGCGGCATGTGTGCCGAGG
TTTTAATACTTCAATCCATA

Product: major facilitator superfamily transporter L-fucose permease

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSISIFLKRVIFRHHERQIMSAQSQNNHTSPLVVLTTLFFMMGFITCMNDILIPHLKEIFDLSYVQAMLIQFCFFTAYAV
MSIPMGAFVGKVGYKNGVIGGFLLTAVGCLLFYPAAGSHSYAVFLGALFILASGVTLLQVAGNPYVTLLAKPGKESATLT
LVQAFNALGTTIAPQIGAFLILADATQTVSKAEQISSVQIPYLGLAGLLIILAVFVKMIRLPDARKIAAEESAHNHDGKT
SVWQYKHLVFGTAGIFCYVGAEVSIGSLMVNVLGYLKGLDHASAAHYLSFYWGGAMVGRFLGSAVMAKFAPNRYLAFNAS
AAVVLLAVAMATGSGNADVAMWSLLAIGFFNSIMFPTIFSLATKGLGKFTNAASGVLCTAIVGGAVVPVVQGWVADTYTL
MSSFVVSVICYLYIVFFAVYGYRADK

Sequences:

>Translated_426_residues
MSISIFLKRVIFRHHERQIMSAQSQNNHTSPLVVLTTLFFMMGFITCMNDILIPHLKEIFDLSYVQAMLIQFCFFTAYAV
MSIPMGAFVGKVGYKNGVIGGFLLTAVGCLLFYPAAGSHSYAVFLGALFILASGVTLLQVAGNPYVTLLAKPGKESATLT
LVQAFNALGTTIAPQIGAFLILADATQTVSKAEQISSVQIPYLGLAGLLIILAVFVKMIRLPDARKIAAEESAHNHDGKT
SVWQYKHLVFGTAGIFCYVGAEVSIGSLMVNVLGYLKGLDHASAAHYLSFYWGGAMVGRFLGSAVMAKFAPNRYLAFNAS
AAVVLLAVAMATGSGNADVAMWSLLAIGFFNSIMFPTIFSLATKGLGKFTNAASGVLCTAIVGGAVVPVVQGWVADTYTL
MSSFVVSVICYLYIVFFAVYGYRADK
>Mature_425_residues
SISIFLKRVIFRHHERQIMSAQSQNNHTSPLVVLTTLFFMMGFITCMNDILIPHLKEIFDLSYVQAMLIQFCFFTAYAVM
SIPMGAFVGKVGYKNGVIGGFLLTAVGCLLFYPAAGSHSYAVFLGALFILASGVTLLQVAGNPYVTLLAKPGKESATLTL
VQAFNALGTTIAPQIGAFLILADATQTVSKAEQISSVQIPYLGLAGLLIILAVFVKMIRLPDARKIAAEESAHNHDGKTS
VWQYKHLVFGTAGIFCYVGAEVSIGSLMVNVLGYLKGLDHASAAHYLSFYWGGAMVGRFLGSAVMAKFAPNRYLAFNASA
AVVLLAVAMATGSGNADVAMWSLLAIGFFNSIMFPTIFSLATKGLGKFTNAASGVLCTAIVGGAVVPVVQGWVADTYTLM
SSFVVSVICYLYIVFFAVYGYRADK

Specific function: Intake of glucose and galactose (Potential) [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=424, Percent_Identity=30.6603773584906, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005964
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45614; Mature: 45483

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISIFLKRVIFRHHERQIMSAQSQNNHTSPLVVLTTLFFMMGFITCMNDILIPHLKEIF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLSYVQAMLIQFCFFTAYAVMSIPMGAFVGKVGYKNGVIGGFLLTAVGCLLFYPAAGSHS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCH
YAVFLGALFILASGVTLLQVAGNPYVTLLAKPGKESATLTLVQAFNALGTTIAPQIGAFL
HHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHCCEE
ILADATQTVSKAEQISSVQIPYLGLAGLLIILAVFVKMIRLPDARKIAAEESAHNHDGKT
EEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
SVWQYKHLVFGTAGIFCYVGAEVSIGSLMVNVLGYLKGLDHASAAHYLSFYWGGAMVGRF
HHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LGSAVMAKFAPNRYLAFNASAAVVLLAVAMATGSGNADVAMWSLLAIGFFNSIMFPTIFS
HHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LATKGLGKFTNAASGVLCTAIVGGAVVPVVQGWVADTYTLMSSFVVSVICYLYIVFFAVY
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYRADK
CCCCCC
>Mature Secondary Structure 
SISIFLKRVIFRHHERQIMSAQSQNNHTSPLVVLTTLFFMMGFITCMNDILIPHLKEIF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLSYVQAMLIQFCFFTAYAVMSIPMGAFVGKVGYKNGVIGGFLLTAVGCLLFYPAAGSHS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCH
YAVFLGALFILASGVTLLQVAGNPYVTLLAKPGKESATLTLVQAFNALGTTIAPQIGAFL
HHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHCCEE
ILADATQTVSKAEQISSVQIPYLGLAGLLIILAVFVKMIRLPDARKIAAEESAHNHDGKT
EEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
SVWQYKHLVFGTAGIFCYVGAEVSIGSLMVNVLGYLKGLDHASAAHYLSFYWGGAMVGRF
HHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LGSAVMAKFAPNRYLAFNASAAVVLLAVAMATGSGNADVAMWSLLAIGFFNSIMFPTIFS
HHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LATKGLGKFTNAASGVLCTAIVGGAVVPVVQGWVADTYTLMSSFVVSVICYLYIVFFAVY
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYRADK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168605 [H]