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The map label for this gene is hecB [H]

Identifier: 161869438

GI number: 161869438

Start: 463749

End: 465491

Strand: Direct

Name: hecB [H]

Synonym: NMCC_0448

Alternate gene names: 161869438

Gene position: 463749-465491 (Clockwise)

Preceding gene: 161869437

Following gene: 161869439

Centisome position: 21.54

GC content: 46.01

Gene sequence:

>1743_bases
ATGAAATTTTTTCCTGCTCCATGTCTGTTGGTTATCCTGGCTGTCATACCCCTTAAAACCTTAGCTGCCGATGAAAACGA
TGCAGAACTTATCCGTTCCATGCAGCGTCAGCAGCACATAGATGCTGAATTGTTAACTGATGCAAATGTCCGTTTCGAGC
AACCATTGGAGAAGAACAATTATGTCCTGAGTGAAGATGAAACACCGTGTACTCGGGTAAATTACATTAGTTTAGATGAT
AAGACGGCGCGCAAATTTTCTTTTCTTCCTTCTGTGCTCATGAAAGAAACAGCTTTTAAAACTGGGATGTGTTTAGGTTC
CAATAATTTGAGCAGGCTACAAAAAGCTGCGCAACAGATACTGATCGTGCGTGGCTACCTCACTTCCCAAGCTATTATCC
AACCACAGAATATGGATTCGGGAATTCTGAAATTACGGGTATCAGCAGGCGAAATAGGGGATATCCGCTATGAAGAAAAA
CGGGATGGGAAGTCTGCCGAAGGCAGTATTAGTACATTCAATAACAAATTTCCCTTATATAGGAACAAAATTCTCAATCT
TCGCGATGTAGAGCAGGGCTTGGAAAACCTGCGTCGTTTGTCGAGTGTTAAAACAGATATTCAGATTATACCGTCCGAAG
AAGAAGGCAAAAGCGATTTACAGATCAAATGGCAGCAGAATAAACCCATACGGTTCAGTATCGGTATAGATGATGCGGGC
GGCAAAACGACCGGCAAATATCAAGGAAATGTCGCTTTATCGTTCGATAACCCTTTGGGCTTAAGCGATTTGTTTTATGT
TTCATATGGACGCGGTTTGGCGCACAAAACGGACTTGACTGATGCCACCGGTACGGAAACTGCAAGCGGATCCAGAAGTT
ACAGCGTGCATTATTCGGTGCCCGTAAAAAAATGGCTGTTTTCTTTTAATCACAATGGACATCGTTACCACGAAGCAACC
GAAGGCTATTCCGTCAATTACGATTACAACGGCAAACAATATCAGAGCAGCTTGGCCGCCGAGCGCATGCTTTGGCGTAA
CAGGTTTCATAAAACTTCAGTCGGAATGAAATTATGGACACGCCAAACCTATAAATACATCGACGATGCCGAAATCGAAG
TGCAACGCCGCCGCTCTGCAGGCTGGGAAGCCGAATTGCGCCACCGTGCTTACCTCAACCGTTGGCAGCTTGACGGCAAG
TTGTCTTACAAACGCGGGACCGGCATGCGCCAAAGTATGCCTGCACCGGAAGAAAACGGCGGCAATATTCTTCCAGGTAC
ATCTCGTATGAAAATCATTACTGCCGGTTTGGACGCAGCCGCCCCATTTATTTTAGGCAAACAGCAGTTTTTCTACGCAA
CCGCCATTCAAGCTCAATGGAACAAAACGCCGTTGGTTGCCCAAGATAAATTGTCAATCGGCAGCCGCTACACCGTTCGC
GGATTTGATGGGGAGCAGAGTCTTTTCGGAGAGCGAGGTTTCTACTGGCAGAATACTTTAACTTGGTATTTTCATCCGAA
CCATCAGTTCTATCTCGGTGCGGACTATGGCCGCGTATCTGGCGAAAGTGCACAATATGTATCGGGCAAGCAGCTGATGG
GTGCAGTGGTCGGCTTCAGAGGAGGGCATAAAGTAGGCGGTATGTTTGCTTATGATCTGTTTGCCGGCAAGCCGCTTCAT
AAACCCAAAGGCTTTCAGACGACCAACACCGTTTACGGCTTCAACTTGAATTACAGTTTCTAA

Upstream 100 bases:

>100_bases
TGGGAATTTTGGGGAATTTTGCAAAGGTCTCATTCTATAACTGTAAATACTTTTAAATTTATGACAAAATAGTAAATATT
GCTAAAATAATATTGATGTC

Downstream 100 bases:

>100_bases
CCTCTGAATTTTTTTACTGATATTTAGACGGTCTTTCCTTATCCTCAGACCGTCAAACTTTACCTACGTACTTGGCGCGC
AGTACGTTCATCTTCAAAAT

Product: hemolysin activation protein HecB, putative

Products: NA

Alternate protein names: TpsB transporter [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MKFFPAPCLLVILAVIPLKTLAADENDAELIRSMQRQQHIDAELLTDANVRFEQPLEKNNYVLSEDETPCTRVNYISLDD
KTARKFSFLPSVLMKETAFKTGMCLGSNNLSRLQKAAQQILIVRGYLTSQAIIQPQNMDSGILKLRVSAGEIGDIRYEEK
RDGKSAEGSISTFNNKFPLYRNKILNLRDVEQGLENLRRLSSVKTDIQIIPSEEEGKSDLQIKWQQNKPIRFSIGIDDAG
GKTTGKYQGNVALSFDNPLGLSDLFYVSYGRGLAHKTDLTDATGTETASGSRSYSVHYSVPVKKWLFSFNHNGHRYHEAT
EGYSVNYDYNGKQYQSSLAAERMLWRNRFHKTSVGMKLWTRQTYKYIDDAEIEVQRRRSAGWEAELRHRAYLNRWQLDGK
LSYKRGTGMRQSMPAPEENGGNILPGTSRMKIITAGLDAAAPFILGKQQFFYATAIQAQWNKTPLVAQDKLSIGSRYTVR
GFDGEQSLFGERGFYWQNTLTWYFHPNHQFYLGADYGRVSGESAQYVSGKQLMGAVVGFRGGHKVGGMFAYDLFAGKPLH
KPKGFQTTNTVYGFNLNYSF

Sequences:

>Translated_580_residues
MKFFPAPCLLVILAVIPLKTLAADENDAELIRSMQRQQHIDAELLTDANVRFEQPLEKNNYVLSEDETPCTRVNYISLDD
KTARKFSFLPSVLMKETAFKTGMCLGSNNLSRLQKAAQQILIVRGYLTSQAIIQPQNMDSGILKLRVSAGEIGDIRYEEK
RDGKSAEGSISTFNNKFPLYRNKILNLRDVEQGLENLRRLSSVKTDIQIIPSEEEGKSDLQIKWQQNKPIRFSIGIDDAG
GKTTGKYQGNVALSFDNPLGLSDLFYVSYGRGLAHKTDLTDATGTETASGSRSYSVHYSVPVKKWLFSFNHNGHRYHEAT
EGYSVNYDYNGKQYQSSLAAERMLWRNRFHKTSVGMKLWTRQTYKYIDDAEIEVQRRRSAGWEAELRHRAYLNRWQLDGK
LSYKRGTGMRQSMPAPEENGGNILPGTSRMKIITAGLDAAAPFILGKQQFFYATAIQAQWNKTPLVAQDKLSIGSRYTVR
GFDGEQSLFGERGFYWQNTLTWYFHPNHQFYLGADYGRVSGESAQYVSGKQLMGAVVGFRGGHKVGGMFAYDLFAGKPLH
KPKGFQTTNTVYGFNLNYSF
>Mature_580_residues
MKFFPAPCLLVILAVIPLKTLAADENDAELIRSMQRQQHIDAELLTDANVRFEQPLEKNNYVLSEDETPCTRVNYISLDD
KTARKFSFLPSVLMKETAFKTGMCLGSNNLSRLQKAAQQILIVRGYLTSQAIIQPQNMDSGILKLRVSAGEIGDIRYEEK
RDGKSAEGSISTFNNKFPLYRNKILNLRDVEQGLENLRRLSSVKTDIQIIPSEEEGKSDLQIKWQQNKPIRFSIGIDDAG
GKTTGKYQGNVALSFDNPLGLSDLFYVSYGRGLAHKTDLTDATGTETASGSRSYSVHYSVPVKKWLFSFNHNGHRYHEAT
EGYSVNYDYNGKQYQSSLAAERMLWRNRFHKTSVGMKLWTRQTYKYIDDAEIEVQRRRSAGWEAELRHRAYLNRWQLDGK
LSYKRGTGMRQSMPAPEENGGNILPGTSRMKIITAGLDAAAPFILGKQQFFYATAIQAQWNKTPLVAQDKLSIGSRYTVR
GFDGEQSLFGERGFYWQNTLTWYFHPNHQFYLGADYGRVSGESAQYVSGKQLMGAVVGFRGGHKVGGMFAYDLFAGKPLH
KPKGFQTTNTVYGFNLNYSF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of filamentous hemagglutinin (FHA) [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 65634; Mature: 65634

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFPAPCLLVILAVIPLKTLAADENDAELIRSMQRQQHIDAELLTDANVRFEQPLEKNN
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHEECCCCCEECCCCCCCC
YVLSEDETPCTRVNYISLDDKTARKFSFLPSVLMKETAFKTGMCLGSNNLSRLQKAAQQI
EEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHE
LIVRGYLTSQAIIQPQNMDSGILKLRVSAGEIGDIRYEEKRDGKSAEGSISTFNNKFPLY
EEEEEECCCCEEECCCCCCCCEEEEEECCCCCCCCEEHHHCCCCCCCCCCEECCCCCCHH
RNKILNLRDVEQGLENLRRLSSVKTDIQIIPSEEEGKSDLQIKWQQNKPIRFSIGIDDAG
HHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCEEEEEECCCCC
GKTTGKYQGNVALSFDNPLGLSDLFYVSYGRGLAHKTDLTDATGTETASGSRSYSVHYSV
CCCCCEECCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
PVKKWLFSFNHNGHRYHEATEGYSVNYDYNGKQYQSSLAAERMLWRNRFHKTSVGMKLWT
CHHHHHHHCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RQTYKYIDDAEIEVQRRRSAGWEAELRHRAYLNRWQLDGKLSYKRGTGMRQSMPAPEENG
HHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHHHEEECCEEEECCCCCCHHCCCCCCCCC
GNILPGTSRMKIITAGLDAAAPFILGKQQFFYATAIQAQWNKTPLVAQDKLSIGSRYTVR
CCCCCCCCCEEEEEECCCHHCCCEECCCEEEEEEEEEECCCCCCCEEECCCCCCCEEEEE
GFDGEQSLFGERGFYWQNTLTWYFHPNHQFYLGADYGRVSGESAQYVSGKQLMGAVVGFR
CCCCCHHHHCCCCEEEECEEEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCC
GGHKVGGMFAYDLFAGKPLHKPKGFQTTNTVYGFNLNYSF
CCCCCCCEEEEHHHCCCCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKFFPAPCLLVILAVIPLKTLAADENDAELIRSMQRQQHIDAELLTDANVRFEQPLEKNN
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHEECCCCCEECCCCCCCC
YVLSEDETPCTRVNYISLDDKTARKFSFLPSVLMKETAFKTGMCLGSNNLSRLQKAAQQI
EEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHE
LIVRGYLTSQAIIQPQNMDSGILKLRVSAGEIGDIRYEEKRDGKSAEGSISTFNNKFPLY
EEEEEECCCCEEECCCCCCCCEEEEEECCCCCCCCEEHHHCCCCCCCCCCEECCCCCCHH
RNKILNLRDVEQGLENLRRLSSVKTDIQIIPSEEEGKSDLQIKWQQNKPIRFSIGIDDAG
HHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCEEEEEECCCCC
GKTTGKYQGNVALSFDNPLGLSDLFYVSYGRGLAHKTDLTDATGTETASGSRSYSVHYSV
CCCCCEECCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
PVKKWLFSFNHNGHRYHEATEGYSVNYDYNGKQYQSSLAAERMLWRNRFHKTSVGMKLWT
CHHHHHHHCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RQTYKYIDDAEIEVQRRRSAGWEAELRHRAYLNRWQLDGKLSYKRGTGMRQSMPAPEENG
HHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHHHEEECCEEEECCCCCCHHCCCCCCCCC
GNILPGTSRMKIITAGLDAAAPFILGKQQFFYATAIQAQWNKTPLVAQDKLSIGSRYTVR
CCCCCCCCCEEEEEECCCHHCCCEECCCEEEEEEEEEECCCCCCCEEECCCCCCCEEEEE
GFDGEQSLFGERGFYWQNTLTWYFHPNHQFYLGADYGRVSGESAQYVSGKQLMGAVVGFR
CCCCCHHHHCCCCEEEECEEEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCC
GGHKVGGMFAYDLFAGKPLHKPKGFQTTNTVYGFNLNYSF
CCCCCCCEEEEHHHCCCCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]