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The map label for this gene is rssA [H]

Identifier: 161869426

GI number: 161869426

Start: 451516

End: 452736

Strand: Direct

Name: rssA [H]

Synonym: NMCC_0434

Alternate gene names: 161869426

Gene position: 451516-452736 (Clockwise)

Preceding gene: 161869425

Following gene: 161869428

Centisome position: 20.97

GC content: 56.35

Gene sequence:

>1221_bases
ATGTTTTCCTACTACGAAACCTTCCACGAAACGGAAGCGTTGCAGGACGACCTGCTCCGTCAGGCGGCATTGTACGTCGC
CCCCGATTCCAAACCCGAAACTTTGCCCGAGGGCGACGGCGATACGCGTATTTTGGTACAGATGCCGCAGCAGGAAGACC
CTGTTGTCAGCCTGCCTGCGCATCTGGCGGACGGTCTGCACACGCTTCAGGCGGACGGGGACGACGATTATTACCGCGTC
TATATCCGCACGACCGAACAGGGACGGATTGCCGTTATGCAGGAAAACGAATACCGTGAAGATTTGGCGGCGGATGCGGC
ACGGCAAAGCGTGTTGCCCCTGCTGGCGGCACTGCCGCTGATGATACTGCTGACCGTGTGGATTACGCACAAAGCCATGC
GCCCCGTCCGCAAATTGTCGCAAAGTCTCGAACAACGCCGAATCAATGACCTGTCTGCTTTGAGTGTGGACAATATTCCC
AGTGAAATCAGAGGGTTCGTAACCGCCATCAACCTGCTTTTGAAACGTGCGGATGAAGACATCCGCCACCGTCAGCGGTT
TGTCGCCGACGCGGCACACGAATTGCGTACGCCGATGACAGCCCTTTCCCTTCAGGCGGAACGGCTCAACAATATGTCGC
TCCCACCCGATGCAGCGCGGCAGCCTGCCGTTTTGCAGCAGAGCATCAGGCGCAACAAACACCTGCTCGAACAGCTTTTG
GCACTGGCGCGTTCGCAGTCGGACGAAACCCCTCTGACGAAAACGACATTCGGTCTGCAAAGCCGTTTCCGCCAAGTGTT
GCAGGAACTGATGCCGCTGGCTTTGGAAAAACGTCAGGACATCGGTGTGGCGGTCAGAGGCGATGTCGAAGTGTCTGCCG
ACGAAACAGAAATCTATACGCTGATTAAAACCTTTGCCGATAACGCGGTACGTTACACGCCGCCTGAAGGCAGGATAGAT
TTGGGTTTCACAGACGAAGGGAAATATCTTGCCGTGTGGGTGGAAGATAACGGGAACGGCATTCCCGAATCCGAACGCGC
CCGCGTCCTCGATCCGTTTTACCGTATTTTGGGAACGGAGCAGCAGGGGACGGGGCTGGGTCTGTCCATCGCCGACACGC
TTGCCAAAAAATACGGCGGACATTTGGAACTGACCGACAGCCGACGTTTCGGACACGGTCTGTTGATACGGGCGTTGTTG
GACAAGGAAACCCTGAAATAG

Upstream 100 bases:

>100_bases
CGCGGCTGCCGCTGCCCAGCCTTATGACTTGATGCTGCTGGATTTGGGTTTGCCGGGGCGGACGGTTTGGATGTTTGTTC
CGCTGGCAATGCTTGCAGGT

Downstream 100 bases:

>100_bases
ACAGATGCCGTCTGAAGGCTTCAGACGGCATTTTTTACATCAGCACTATATCGTATTGTTCCTGCGTGTAAGCGGTTTCG
ACCGCCAGAGAAATCGGTTT

Product: OmpR family two-component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MFSYYETFHETEALQDDLLRQAALYVAPDSKPETLPEGDGDTRILVQMPQQEDPVVSLPAHLADGLHTLQADGDDDYYRV
YIRTTEQGRIAVMQENEYREDLAADAARQSVLPLLAALPLMILLTVWITHKAMRPVRKLSQSLEQRRINDLSALSVDNIP
SEIRGFVTAINLLLKRADEDIRHRQRFVADAAHELRTPMTALSLQAERLNNMSLPPDAARQPAVLQQSIRRNKHLLEQLL
ALARSQSDETPLTKTTFGLQSRFRQVLQELMPLALEKRQDIGVAVRGDVEVSADETEIYTLIKTFADNAVRYTPPEGRID
LGFTDEGKYLAVWVEDNGNGIPESERARVLDPFYRILGTEQQGTGLGLSIADTLAKKYGGHLELTDSRRFGHGLLIRALL
DKETLK

Sequences:

>Translated_406_residues
MFSYYETFHETEALQDDLLRQAALYVAPDSKPETLPEGDGDTRILVQMPQQEDPVVSLPAHLADGLHTLQADGDDDYYRV
YIRTTEQGRIAVMQENEYREDLAADAARQSVLPLLAALPLMILLTVWITHKAMRPVRKLSQSLEQRRINDLSALSVDNIP
SEIRGFVTAINLLLKRADEDIRHRQRFVADAAHELRTPMTALSLQAERLNNMSLPPDAARQPAVLQQSIRRNKHLLEQLL
ALARSQSDETPLTKTTFGLQSRFRQVLQELMPLALEKRQDIGVAVRGDVEVSADETEIYTLIKTFADNAVRYTPPEGRID
LGFTDEGKYLAVWVEDNGNGIPESERARVLDPFYRILGTEQQGTGLGLSIADTLAKKYGGHLELTDSRRFGHGLLIRALL
DKETLK
>Mature_406_residues
MFSYYETFHETEALQDDLLRQAALYVAPDSKPETLPEGDGDTRILVQMPQQEDPVVSLPAHLADGLHTLQADGDDDYYRV
YIRTTEQGRIAVMQENEYREDLAADAARQSVLPLLAALPLMILLTVWITHKAMRPVRKLSQSLEQRRINDLSALSVDNIP
SEIRGFVTAINLLLKRADEDIRHRQRFVADAAHELRTPMTALSLQAERLNNMSLPPDAARQPAVLQQSIRRNKHLLEQLL
ALARSQSDETPLTKTTFGLQSRFRQVLQELMPLALEKRQDIGVAVRGDVEVSADETEIYTLIKTFADNAVRYTPPEGRID
LGFTDEGKYLAVWVEDNGNGIPESERARVLDPFYRILGTEQQGTGLGLSIADTLAKKYGGHLELTDSRRFGHGLLIRALL
DKETLK

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=335, Percent_Identity=31.6417910447761, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790551, Length=289, Percent_Identity=28.719723183391, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788279, Length=358, Percent_Identity=25.4189944134078, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=25.6637168141593, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=284, Percent_Identity=25.3521126760563, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082128, Length=295, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=334, Percent_Identity=22.7544910179641, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=209, Percent_Identity=28.2296650717703, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=25.5411255411255, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=273, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=267, Percent_Identity=24.3445692883895, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=279, Percent_Identity=25.4480286738351, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=29.3388429752066, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=216, Percent_Identity=25.462962962963, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45702; Mature: 45702

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSYYETFHETEALQDDLLRQAALYVAPDSKPETLPEGDGDTRILVQMPQQEDPVVSLPA
CCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCH
HLADGLHTLQADGDDDYYRVYIRTTEQGRIAVMQENEYREDLAADAARQSVLPLLAALPL
HHHCCHHHHCCCCCCCEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
MILLTVWITHKAMRPVRKLSQSLEQRRINDLSALSVDNIPSEIRGFVTAINLLLKRADED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHH
IRHRQRFVADAAHELRTPMTALSLQAERLNNMSLPPDAARQPAVLQQSIRRNKHLLEQLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALARSQSDETPLTKTTFGLQSRFRQVLQELMPLALEKRQDIGVAVRGDVEVSADETEIYT
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECCCHHHHHH
LIKTFADNAVRYTPPEGRIDLGFTDEGKYLAVWVEDNGNGIPESERARVLDPFYRILGTE
HHHHHHCCCEEECCCCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
QQGTGLGLSIADTLAKKYGGHLELTDSRRFGHGLLIRALLDKETLK
CCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFSYYETFHETEALQDDLLRQAALYVAPDSKPETLPEGDGDTRILVQMPQQEDPVVSLPA
CCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCH
HLADGLHTLQADGDDDYYRVYIRTTEQGRIAVMQENEYREDLAADAARQSVLPLLAALPL
HHHCCHHHHCCCCCCCEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
MILLTVWITHKAMRPVRKLSQSLEQRRINDLSALSVDNIPSEIRGFVTAINLLLKRADED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHH
IRHRQRFVADAAHELRTPMTALSLQAERLNNMSLPPDAARQPAVLQQSIRRNKHLLEQLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALARSQSDETPLTKTTFGLQSRFRQVLQELMPLALEKRQDIGVAVRGDVEVSADETEIYT
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECCCHHHHHH
LIKTFADNAVRYTPPEGRIDLGFTDEGKYLAVWVEDNGNGIPESERARVLDPFYRILGTE
HHHHHHCCCEEECCCCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
QQGTGLGLSIADTLAKKYGGHLELTDSRRFGHGLLIRALLDKETLK
CCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA