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The map label for this gene is avtA [H]

Identifier: 161869395

GI number: 161869395

Start: 411973

End: 413454

Strand: Reverse

Name: avtA [H]

Synonym: NMCC_0402

Alternate gene names: 161869395

Gene position: 413454-411973 (Counterclockwise)

Preceding gene: 161869396

Following gene: 161869391

Centisome position: 19.2

GC content: 57.22

Gene sequence:

>1482_bases
GTGCGGCCTGCGACCGTTACGACCAGCAGGCAATCCGCACCCTGCTCATCAACGCCCCGACCGGCTTTGCCCCGAGCGAC
GGCATCTGCGACCTGCTTTGGGTACGAGAAACACACAGAAAAAATGCCGTCTGAACCTTCAGACGGCATAACGTACAAAC
CAACCTACCTTACACACACGGAGTTTGACATGCAGTTTTCAGCATTCGGCGAAAAATTCACGCAACACAGCGGCATCCTC
CAACTGATGGACGACCTCGGCGACGCGCTCAAAAGCGACAAACCCGTCAACATGCTCGGCGGCGGCAATCCGGCGCGCAT
TCCGGAAATCGATCGGGCGTTCGCCGACATATTCTCCAAGCTGGCGGCGGAACACGCCGTCGAGAACATCGGCAACTACT
CCAACCCCCAAGGCGATGCCGCGCTGATTGACGCGCTGACCGCCTTCCTCAACCGCGAATACGGCTGGAACCTGACCGCC
GGCAATATCGCGCTGACCAACGGTTCGCAAAACGCGTTTTTCTATTTGTTCAACCTCTTCGGCGGCAAATTCAAGCTTTC
AGACGGCACATCCGCAGAAAAAGCCATCCTGCTGCCGCTCGCGCCCGAATACATCGGCTATGCCGACGTACATATCGAAG
GACGGCACTTCGTTTCCGTCAAACCCAAAATCGAAAACGTCGAACACGAAGGCGAAACCGGCTTCTTCAAATACCGCGTG
GACTTTGACGCACTGGAAAACCTGCCCGAGCTGAAAGAAGGCAAAATCGGCGCAATCTGTTGTTCGCGCCCGACCAACCC
GACCGGCAATGTGCTGACCGACGGCGAAATGGCGCGTTTGGACGCTTTGGCGCAAAAACACGGCATTCCGCTGATTATCG
ACAACGCCTACGGAATGCCGTTCCCCAACATCATTTACAGCGACGTTACGCTGAATTGGCACGAAAACATCATCCTCTGC
TTCAGCCTTTCCAAAGTCGGCTTACCGGGCGTGCGCACCGGCATCATCGTCGCCGCGCCCGAAGTCGTCAAAGCCGTCAG
CAGCCTGAACGCGATTGTAAACCTTGCCCCCACGCGCTTCGGCGCGGCCATCGCCGCCCCGCTACTGGAAAGCGGCGAGA
TGAAACGGCTTGCCGACCAAGTCATCCGGCCGTTTTACCGCAATCAGGCGCAAACCGCCGTCTCGCTGCTCAAGCGGGAG
CTGGGCGCGTACCCGATGAAAATCCACAAACCCGAAGGCGCGATTTTCCTGTGGCTCTGGTTTGAAAACCTGCCCGTTTC
TTCGCAAACCCTGTACGAAATGCTCAAAGCCGAAGGCACGCTGATTATTCCGGGCGAGCATTTCTTCGTCGGCATCGACA
CGCAGGATTACCCGCACGCAGGCGAGTGCATCCGCATGAGCATCGCGCAGGACGCTCAAACGCTGGAAAAAGGCATTGCC
GCCATCGGTAAAACCGTCCGAAAACTGTACGACAACGTTTAA

Upstream 100 bases:

>100_bases
ATCGGCGACAACGTCCGCAAAACCGGCCATCCGCGCATCATGACCGCCAACGAGACCATGCTGCCGTGGCACGAGCTCTC
CGCCCTGCTCGACCGCATCC

Downstream 100 bases:

>100_bases
AACGCAAAAAATGCCGTCTGAAAGCCTTTCAGACGGCATTTTTATCCGCATTCAATGTCGGGAAAAATGCGCCCACACCG
GCCTACAGTTTTCCGGCAGC

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MRPATVTTSRQSAPCSSTPRPALPRATASATCFGYEKHTEKMPSEPSDGITYKPTYLTHTEFDMQFSAFGEKFTQHSGIL
QLMDDLGDALKSDKPVNMLGGGNPARIPEIDRAFADIFSKLAAEHAVENIGNYSNPQGDAALIDALTAFLNREYGWNLTA
GNIALTNGSQNAFFYLFNLFGGKFKLSDGTSAEKAILLPLAPEYIGYADVHIEGRHFVSVKPKIENVEHEGETGFFKYRV
DFDALENLPELKEGKIGAICCSRPTNPTGNVLTDGEMARLDALAQKHGIPLIIDNAYGMPFPNIIYSDVTLNWHENIILC
FSLSKVGLPGVRTGIIVAAPEVVKAVSSLNAIVNLAPTRFGAAIAAPLLESGEMKRLADQVIRPFYRNQAQTAVSLLKRE
LGAYPMKIHKPEGAIFLWLWFENLPVSSQTLYEMLKAEGTLIIPGEHFFVGIDTQDYPHAGECIRMSIAQDAQTLEKGIA
AIGKTVRKLYDNV

Sequences:

>Translated_493_residues
MRPATVTTSRQSAPCSSTPRPALPRATASATCFGYEKHTEKMPSEPSDGITYKPTYLTHTEFDMQFSAFGEKFTQHSGIL
QLMDDLGDALKSDKPVNMLGGGNPARIPEIDRAFADIFSKLAAEHAVENIGNYSNPQGDAALIDALTAFLNREYGWNLTA
GNIALTNGSQNAFFYLFNLFGGKFKLSDGTSAEKAILLPLAPEYIGYADVHIEGRHFVSVKPKIENVEHEGETGFFKYRV
DFDALENLPELKEGKIGAICCSRPTNPTGNVLTDGEMARLDALAQKHGIPLIIDNAYGMPFPNIIYSDVTLNWHENIILC
FSLSKVGLPGVRTGIIVAAPEVVKAVSSLNAIVNLAPTRFGAAIAAPLLESGEMKRLADQVIRPFYRNQAQTAVSLLKRE
LGAYPMKIHKPEGAIFLWLWFENLPVSSQTLYEMLKAEGTLIIPGEHFFVGIDTQDYPHAGECIRMSIAQDAQTLEKGIA
AIGKTVRKLYDNV
>Mature_493_residues
MRPATVTTSRQSAPCSSTPRPALPRATASATCFGYEKHTEKMPSEPSDGITYKPTYLTHTEFDMQFSAFGEKFTQHSGIL
QLMDDLGDALKSDKPVNMLGGGNPARIPEIDRAFADIFSKLAAEHAVENIGNYSNPQGDAALIDALTAFLNREYGWNLTA
GNIALTNGSQNAFFYLFNLFGGKFKLSDGTSAEKAILLPLAPEYIGYADVHIEGRHFVSVKPKIENVEHEGETGFFKYRV
DFDALENLPELKEGKIGAICCSRPTNPTGNVLTDGEMARLDALAQKHGIPLIIDNAYGMPFPNIIYSDVTLNWHENIILC
FSLSKVGLPGVRTGIIVAAPEVVKAVSSLNAIVNLAPTRFGAAIAAPLLESGEMKRLADQVIRPFYRNQAQTAVSLLKRE
LGAYPMKIHKPEGAIFLWLWFENLPVSSQTLYEMLKAEGTLIIPGEHFFVGIDTQDYPHAGECIRMSIAQDAQTLEKGIA
AIGKTVRKLYDNV

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=428, Percent_Identity=47.196261682243, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 53962; Mature: 53962

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPATVTTSRQSAPCSSTPRPALPRATASATCFGYEKHTEKMPSEPSDGITYKPTYLTHT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCCCEEECCEEEECC
EFDMQFSAFGEKFTQHSGILQLMDDLGDALKSDKPVNMLGGGNPARIPEIDRAFADIFSK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHH
LAAEHAVENIGNYSNPQGDAALIDALTAFLNREYGWNLTAGNIALTNGSQNAFFYLFNLF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCEEEEEEECC
GGKFKLSDGTSAEKAILLPLAPEYIGYADVHIEGRHFVSVKPKIENVEHEGETGFFKYRV
CCEEEECCCCCCCCEEEEEECHHHCCEEEEEECCCEEEEECCCCCCCCCCCCCCEEEEEE
DFDALENLPELKEGKIGAICCSRPTNPTGNVLTDGEMARLDALAQKHGIPLIIDNAYGMP
CHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEECCHHHHHHHHHHHCCCCEEEECCCCCC
FPNIIYSDVTLNWHENIILCFSLSKVGLPGVRTGIIVAAPEVVKAVSSLNAIVNLAPTRF
CCCEEEECEEEECCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHH
GAAIAAPLLESGEMKRLADQVIRPFYRNQAQTAVSLLKRELGAYPMKIHKPEGAIFLWLW
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEE
FENLPVSSQTLYEMLKAEGTLIIPGEHFFVGIDTQDYPHAGECIRMSIAQDAQTLEKGIA
ECCCCCCHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCCHHEEHHHHHHHHHHHHHHH
AIGKTVRKLYDNV
HHHHHHHHHHCCC
>Mature Secondary Structure
MRPATVTTSRQSAPCSSTPRPALPRATASATCFGYEKHTEKMPSEPSDGITYKPTYLTHT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCCCEEECCEEEECC
EFDMQFSAFGEKFTQHSGILQLMDDLGDALKSDKPVNMLGGGNPARIPEIDRAFADIFSK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHH
LAAEHAVENIGNYSNPQGDAALIDALTAFLNREYGWNLTAGNIALTNGSQNAFFYLFNLF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCEEEEEEECC
GGKFKLSDGTSAEKAILLPLAPEYIGYADVHIEGRHFVSVKPKIENVEHEGETGFFKYRV
CCEEEECCCCCCCCEEEEEECHHHCCEEEEEECCCEEEEECCCCCCCCCCCCCCEEEEEE
DFDALENLPELKEGKIGAICCSRPTNPTGNVLTDGEMARLDALAQKHGIPLIIDNAYGMP
CHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEECCHHHHHHHHHHHCCCCEEEECCCCCC
FPNIIYSDVTLNWHENIILCFSLSKVGLPGVRTGIIVAAPEVVKAVSSLNAIVNLAPTRF
CCCEEEECEEEECCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHH
GAAIAAPLLESGEMKRLADQVIRPFYRNQAQTAVSLLKRELGAYPMKIHKPEGAIFLWLW
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEE
FENLPVSSQTLYEMLKAEGTLIIPGEHFFVGIDTQDYPHAGECIRMSIAQDAQTLEKGIA
ECCCCCCHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCCHHEEHHHHHHHHHHHHHHH
AIGKTVRKLYDNV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]