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The map label for this gene is argA [H]

Identifier: 161869339

GI number: 161869339

Start: 346384

End: 347694

Strand: Reverse

Name: argA [H]

Synonym: NMCC_0345

Alternate gene names: 161869339

Gene position: 347694-346384 (Counterclockwise)

Preceding gene: 161869340

Following gene: 161869338

Centisome position: 16.15

GC content: 63.62

Gene sequence:

>1311_bases
ATGATCGTGCCCGACCTCTTTGTCGCCCACTTCCGCGAAGCCGCCCCCTACATCCGCCAAATGCGCGGCAAAACGCTGGT
CGCCGGCATAGACGACCGCCTGCTCGAAGGCGATACCTTAAACAAGCTCGCCGCCGACATCGGGCTGTTGTCGCAACTGG
GCATCAGGCTCGTCCTCATCCACGGCGCGCGCCACTTCCTCGACCGCCACGCCGCCGCGCAAGGCCGCACGCCGCATTAT
TGCCGGGGCTTGCGCGTTACCGACGAAACCTCGCTCGAACAGGCGCAGCAGTTTGCCGGCACCGTCCGCAGCCGTTTTGA
AGCCGCATTGTGCGGCAGCGTTTCCGGGTTCGCGCGCGCGCCTTCCGTCCCGCTCGTATCGGGCAACTTCCTGACCGCCC
GTCCGATAGGTGTGATTGACGGAACCGATATGGAATACGCGGGCGTTATCCGCAAAACCGACACCGCCGCCCTCCGTTTC
CAACTCGACGCGGGCAATATCGTCTGGCTGCCGCCGCTCGGACATTCCTACGGCGGCAAGACCTTACATCTCGATATGCT
TCAAACCGCCGCCTCCGCCGCCGTCTCGCTTCAGGCCGAAAAACTCGTTTACCTGACCCTTTCAGACGGCATTGCCCGCC
CCGACGGCACGCTCGCCGAAACCCTCTCGGCGCAGGAAGCGCAATCGCTGGCGGAACACGCCGGCGGCGAAACGCGACGG
CTGATTTCGTCCGCCGTTGCCGCGCTCGAAGGCGGCGTGCATCGCGTCCAAATCCTCAACGGAGCCGCCGACGGCAGCCT
GCTGCAAGAACTCTTCACCCGCAACGGCATCGGCACGTCCATTGCCAAAGAAGCCTTCGTCTCCATCCGGCAGGCGCACA
GCGGCGACATCCCGCACATTGCCGCCCTCATCCGCCCGCTGGAAGAACAGGGCATCCTGCTGCACCGCAGCCGCGAATAC
CTCGAAAACCACATTTCCGAATTTTCCATCCTCGAACACGACGGCAACCTGTACGGTTGCGCCGCCCTGAAAACCTTTGC
CGAAGCCGATTGCGGCGAAATCGCCTGCCTTGCCGTCTCGCCGCAGGCACAGGACGGCGGCTACGGCGAACGCCTGCTTG
CCCACATTATCGATAAGGCGCGCGGCATAGGCATAAGCAGGCTGTTCGCCCTCTCCACAAATACCGGCGAATGGTTTGCC
GAACGCGGCTTTCAGACGGCATCGGAAGCCGAGTTGCCCGAAGCGCGGCGCAAAGCCTACCGCAACAACGGACGGAACTC
GCATATTCTGGTGCGTCGCCTGCACCGCTGA

Upstream 100 bases:

>100_bases
CGCCCGCCGCGCCCGCCCGTCAGGATGGGTTCAACTGGACGATTGCAACCCTGTTTGCCCTTATCGTCCTCATTATGCAG
CTTTCCTACCTCGTCATCCT

Downstream 100 bases:

>100_bases
CCGCAACGGAAAGCCGCCGCAGAAATGCCGTCTGAACCCCGTTTCAGACGGCATTTCCCCGATTATAAAGACCTGCCCAA
CCCTCAAGGACCCCGATGAA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MIVPDLFVAHFREAAPYIRQMRGKTLVAGIDDRLLEGDTLNKLAADIGLLSQLGIRLVLIHGARHFLDRHAAAQGRTPHY
CRGLRVTDETSLEQAQQFAGTVRSRFEAALCGSVSGFARAPSVPLVSGNFLTARPIGVIDGTDMEYAGVIRKTDTAALRF
QLDAGNIVWLPPLGHSYGGKTLHLDMLQTAASAAVSLQAEKLVYLTLSDGIARPDGTLAETLSAQEAQSLAEHAGGETRR
LISSAVAALEGGVHRVQILNGAADGSLLQELFTRNGIGTSIAKEAFVSIRQAHSGDIPHIAALIRPLEEQGILLHRSREY
LENHISEFSILEHDGNLYGCAALKTFAEADCGEIACLAVSPQAQDGGYGERLLAHIIDKARGIGISRLFALSTNTGEWFA
ERGFQTASEAELPEARRKAYRNNGRNSHILVRRLHR

Sequences:

>Translated_436_residues
MIVPDLFVAHFREAAPYIRQMRGKTLVAGIDDRLLEGDTLNKLAADIGLLSQLGIRLVLIHGARHFLDRHAAAQGRTPHY
CRGLRVTDETSLEQAQQFAGTVRSRFEAALCGSVSGFARAPSVPLVSGNFLTARPIGVIDGTDMEYAGVIRKTDTAALRF
QLDAGNIVWLPPLGHSYGGKTLHLDMLQTAASAAVSLQAEKLVYLTLSDGIARPDGTLAETLSAQEAQSLAEHAGGETRR
LISSAVAALEGGVHRVQILNGAADGSLLQELFTRNGIGTSIAKEAFVSIRQAHSGDIPHIAALIRPLEEQGILLHRSREY
LENHISEFSILEHDGNLYGCAALKTFAEADCGEIACLAVSPQAQDGGYGERLLAHIIDKARGIGISRLFALSTNTGEWFA
ERGFQTASEAELPEARRKAYRNNGRNSHILVRRLHR
>Mature_436_residues
MIVPDLFVAHFREAAPYIRQMRGKTLVAGIDDRLLEGDTLNKLAADIGLLSQLGIRLVLIHGARHFLDRHAAAQGRTPHY
CRGLRVTDETSLEQAQQFAGTVRSRFEAALCGSVSGFARAPSVPLVSGNFLTARPIGVIDGTDMEYAGVIRKTDTAALRF
QLDAGNIVWLPPLGHSYGGKTLHLDMLQTAASAAVSLQAEKLVYLTLSDGIARPDGTLAETLSAQEAQSLAEHAGGETRR
LISSAVAALEGGVHRVQILNGAADGSLLQELFTRNGIGTSIAKEAFVSIRQAHSGDIPHIAALIRPLEEQGILLHRSREY
LENHISEFSILEHDGNLYGCAALKTFAEADCGEIACLAVSPQAQDGGYGERLLAHIIDKARGIGISRLFALSTNTGEWFA
ERGFQTASEAELPEARRKAYRNNGRNSHILVRRLHR

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=435, Percent_Identity=40.4597701149425, Blast_Score=303, Evalue=2e-83,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 47128; Mature: 47128

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVPDLFVAHFREAAPYIRQMRGKTLVAGIDDRLLEGDTLNKLAADIGLLSQLGIRLVLI
CCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHCCEEEEE
HGARHFLDRHAAAQGRTPHYCRGLRVTDETSLEQAQQFAGTVRSRFEAALCGSVSGFARA
HHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PSVPLVSGNFLTARPIGVIDGTDMEYAGVIRKTDTAALRFQLDAGNIVWLPPLGHSYGGK
CCCCEECCCEEEECCCEEECCCCCHHHHHEEECCCEEEEEEECCCCEEEECCCCCCCCCC
TLHLDMLQTAASAAVSLQAEKLVYLTLSDGIARPDGTLAETLSAQEAQSLAEHAGGETRR
EEEHHHHHHHHHHHHEEEECEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LISSAVAALEGGVHRVQILNGAADGSLLQELFTRNGIGTSIAKEAFVSIRQAHSGDIPHI
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHH
AALIRPLEEQGILLHRSREYLENHISEFSILEHDGNLYGCAALKTFAEADCGEIACLAVS
HHHHHHHHHCCEEEHHHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHCCCCCCEEEEEEC
PQAQDGGYGERLLAHIIDKARGIGISRLFALSTNTGEWFAERGFQTASEAELPEARRKAY
CCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHH
RNNGRNSHILVRRLHR
HCCCCCCCHHHHECCC
>Mature Secondary Structure
MIVPDLFVAHFREAAPYIRQMRGKTLVAGIDDRLLEGDTLNKLAADIGLLSQLGIRLVLI
CCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHCCEEEEE
HGARHFLDRHAAAQGRTPHYCRGLRVTDETSLEQAQQFAGTVRSRFEAALCGSVSGFARA
HHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PSVPLVSGNFLTARPIGVIDGTDMEYAGVIRKTDTAALRFQLDAGNIVWLPPLGHSYGGK
CCCCEECCCEEEECCCEEECCCCCHHHHHEEECCCEEEEEEECCCCEEEECCCCCCCCCC
TLHLDMLQTAASAAVSLQAEKLVYLTLSDGIARPDGTLAETLSAQEAQSLAEHAGGETRR
EEEHHHHHHHHHHHHEEEECEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LISSAVAALEGGVHRVQILNGAADGSLLQELFTRNGIGTSIAKEAFVSIRQAHSGDIPHI
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHH
AALIRPLEEQGILLHRSREYLENHISEFSILEHDGNLYGCAALKTFAEADCGEIACLAVS
HHHHHHHHHCCEEEHHHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHCCCCCCEEEEEEC
PQAQDGGYGERLLAHIIDKARGIGISRLFALSTNTGEWFAERGFQTASEAELPEARRKAY
CCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHH
RNNGRNSHILVRRLHR
HCCCCCCCHHHHECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]