Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 161869296

GI number: 161869296

Start: 310616

End: 311542

Strand: Reverse

Name: fabD [H]

Synonym: NMCC_0301

Alternate gene names: 161869296

Gene position: 311542-310616 (Counterclockwise)

Preceding gene: 161869297

Following gene: 161869295

Centisome position: 14.47

GC content: 59.33

Gene sequence:

>927_bases
ATGTCTTTTGCCTTCTTTTTTCCCGGACAAGGTTCCCAAAGCCTCGGTATGATGAACGGCTTTGCCGAACACGCCATCGT
CAAAAACACATTTGACGAAGCCTCCGCCATATTAGGGCAGGACTTGTGGGCGATGATTAACGGCAGCGATGCCGAAATCA
TCGGTCAAACCGTCAATACCCAACCCATCATGCTCGCCGCCGGCGTTGCCGTTTACCGCGCCTATTTGGAAGCTGGCGGC
AAAACGCCTGCCGCCGTTGCCGGACACAGCCTCGGCGAATATACCGCGCTTGTCGCCGCCGGCGCATTGGATTTTACAGA
CGCCGTCAAACTCGTACGCCTGCGCGCCGAACTGATGCAGTCTGCCGTACCGCAAGGCGTGGGCGCGATGGCGGCGATTC
TCGGCTTGGAAGATGAACAGGTAAAACAGATTTGCGCCGAAGCCGCCCAAGGCGAAGTGGTCGAAGCCGTCAACTTCAAC
TCGCCCGGACAAGTCGTGATTGCAGGCAACGCCGCCGCCGTCGGACGCGCCATGGCTGCCGCCAAAGAAGCCGGTGCCAA
ACGCGCCCTGCCGCTGCCCGTGTCCGTACCTTCCCATTGCAGCCTGATGAAACCCGCCGCCGACAAACTTGCCGAAGCCC
TGAAAACCGTTGAAATCAAGCAGCCGCAAATCCGCGTTATCCACAACGCCGACGTTGCCGCCTACGATGATGCCGACAAA
ATCAAAGACGCGCTCGTCCGCCAGCTTTACAGCCCCGTACGCTGGACGGAAACCGTCAACGCCCTTGTTTCAGACGGCAT
TGCCGAATCCGCCGAATGCGGACCGGGCAAAGTGTTGGCGGGCTTGGCAAAACGCATCAACAAAACCGCCGCGTGCAGCG
CGCTGACCGATGCCGGACAGATTGCCGCCTTTATCGAAGCGCACTGA

Upstream 100 bases:

>100_bases
GTCCTGATTTTTGTTAATCCACTATATTATTTTGTCCCGCCTGAATTTTTCGTAAAACTCGGGCAGAATACCTGATTATC
CAACCAAACAAAGGAATACT

Downstream 100 bases:

>100_bases
CTTCGTTCTGTAAAAAGCAGCCTACCCTCTTCAGGCTGCTTTTCACGTCCGAACGGCGGCAGCCCCGTATTTACGCTATA
ATCCATCCCGACCAAACCAC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSFAFFFPGQGSQSLGMMNGFAEHAIVKNTFDEASAILGQDLWAMINGSDAEIIGQTVNTQPIMLAAGVAVYRAYLEAGG
KTPAAVAGHSLGEYTALVAAGALDFTDAVKLVRLRAELMQSAVPQGVGAMAAILGLEDEQVKQICAEAAQGEVVEAVNFN
SPGQVVIAGNAAAVGRAMAAAKEAGAKRALPLPVSVPSHCSLMKPAADKLAEALKTVEIKQPQIRVIHNADVAAYDDADK
IKDALVRQLYSPVRWTETVNALVSDGIAESAECGPGKVLAGLAKRINKTAACSALTDAGQIAAFIEAH

Sequences:

>Translated_308_residues
MSFAFFFPGQGSQSLGMMNGFAEHAIVKNTFDEASAILGQDLWAMINGSDAEIIGQTVNTQPIMLAAGVAVYRAYLEAGG
KTPAAVAGHSLGEYTALVAAGALDFTDAVKLVRLRAELMQSAVPQGVGAMAAILGLEDEQVKQICAEAAQGEVVEAVNFN
SPGQVVIAGNAAAVGRAMAAAKEAGAKRALPLPVSVPSHCSLMKPAADKLAEALKTVEIKQPQIRVIHNADVAAYDDADK
IKDALVRQLYSPVRWTETVNALVSDGIAESAECGPGKVLAGLAKRINKTAACSALTDAGQIAAFIEAH
>Mature_307_residues
SFAFFFPGQGSQSLGMMNGFAEHAIVKNTFDEASAILGQDLWAMINGSDAEIIGQTVNTQPIMLAAGVAVYRAYLEAGGK
TPAAVAGHSLGEYTALVAAGALDFTDAVKLVRLRAELMQSAVPQGVGAMAAILGLEDEQVKQICAEAAQGEVVEAVNFNS
PGQVVIAGNAAAVGRAMAAAKEAGAKRALPLPVSVPSHCSLMKPAADKLAEALKTVEIKQPQIRVIHNADVAAYDDADKI
KDALVRQLYSPVRWTETVNALVSDGIAESAECGPGKVLAGLAKRINKTAACSALTDAGQIAAFIEAH

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=33.2236842105263, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=57.3770491803279, Blast_Score=327, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI71984332, Length=292, Percent_Identity=28.4246575342466, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=290, Percent_Identity=26.2068965517241, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665753, Length=307, Percent_Identity=33.5504885993485, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31856; Mature: 31725

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFAFFFPGQGSQSLGMMNGFAEHAIVKNTFDEASAILGQDLWAMINGSDAEIIGQTVNT
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCC
QPIMLAAGVAVYRAYLEAGGKTPAAVAGHSLGEYTALVAAGALDFTDAVKLVRLRAELMQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SAVPQGVGAMAAILGLEDEQVKQICAEAAQGEVVEAVNFNSPGQVVIAGNAAAVGRAMAA
HHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCHHHHHHHHHH
AKEAGAKRALPLPVSVPSHCSLMKPAADKLAEALKTVEIKQPQIRVIHNADVAAYDDADK
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHH
IKDALVRQLYSPVRWTETVNALVSDGIAESAECGPGKVLAGLAKRINKTAACSALTDAGQ
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
IAAFIEAH
HHEEEECC
>Mature Secondary Structure 
SFAFFFPGQGSQSLGMMNGFAEHAIVKNTFDEASAILGQDLWAMINGSDAEIIGQTVNT
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCC
QPIMLAAGVAVYRAYLEAGGKTPAAVAGHSLGEYTALVAAGALDFTDAVKLVRLRAELMQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SAVPQGVGAMAAILGLEDEQVKQICAEAAQGEVVEAVNFNSPGQVVIAGNAAAVGRAMAA
HHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCHHHHHHHHHH
AKEAGAKRALPLPVSVPSHCSLMKPAADKLAEALKTVEIKQPQIRVIHNADVAAYDDADK
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHH
IKDALVRQLYSPVRWTETVNALVSDGIAESAECGPGKVLAGLAKRINKTAACSALTDAGQ
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
IAAFIEAH
HHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]