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The map label for this gene is luxS [H]

Identifier: 161869228

GI number: 161869228

Start: 244181

End: 244687

Strand: Reverse

Name: luxS [H]

Synonym: NMCC_0232

Alternate gene names: 161869228

Gene position: 244687-244181 (Counterclockwise)

Preceding gene: 161869229

Following gene: 161869227

Centisome position: 11.36

GC content: 53.45

Gene sequence:

>507_bases
ATGCCCCTGTTAGACAGTTTCAAAGTCGACCACACCCGTATGTATGCCCCCGCTGTGCGTGTGGCGAAAACCATGACCAC
GCCCAAAGGCGATACCATTACCGTATTCGACCTGCGCTTTTGCGTTCCCAACAAAGAAATCCTGCCTGAAAAAGGCATAC
ACACGCTGGAGCATTTGTTTGCAGGCTTTATGCGCGACCACTTGAACGGCAACGGCGTGGAAATCATCGACATTTCCCCG
ATGGGCTGCCGCACCGGTTTCTACATGAGCCTTATCGGCACGCCTTCCGAACAGCAGGTCGCCGATACGTGGCTGGCTTC
GATGCAAGATGTTTTGACCGTTCAAGACCAAAGCAAAATCCCCGAATTGAACGAATACCAATGCGGCACTTACCTGATGC
ACTCGCTTGCCGAAGCGCAGCAAATCGCGCAAAACGTGTTGGCGCGCAAAGTGGCGGTGAATAAAAACGAAGAGCTGACG
CTGGACGAAGGGCTGCTGAACGCCTAA

Upstream 100 bases:

>100_bases
AGGCGAATGGCCGAAAGTCACAGACCGCGTATTGGACGATGAATTGCAGGACAAAATCCTATCCCGAAAACCTACATAAC
CTACTCAAAAGGATAACACG

Downstream 100 bases:

>100_bases
TCCGCCAAAAATGCCGTCTGAACAAGGGTTTCAGACGGCATTTGCCTTTTCCGTTATAATCCGGGGTTGTGCGGGGGCGG
GTTTTAAGCCGGCATCATCC

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MPLLDSFKVDHTRMYAPAVRVAKTMTTPKGDTITVFDLRFCVPNKEILPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISP
MGCRTGFYMSLIGTPSEQQVADTWLASMQDVLTVQDQSKIPELNEYQCGTYLMHSLAEAQQIAQNVLARKVAVNKNEELT
LDEGLLNA

Sequences:

>Translated_168_residues
MPLLDSFKVDHTRMYAPAVRVAKTMTTPKGDTITVFDLRFCVPNKEILPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISP
MGCRTGFYMSLIGTPSEQQVADTWLASMQDVLTVQDQSKIPELNEYQCGTYLMHSLAEAQQIAQNVLARKVAVNKNEELT
LDEGLLNA
>Mature_167_residues
PLLDSFKVDHTRMYAPAVRVAKTMTTPKGDTITVFDLRFCVPNKEILPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPM
GCRTGFYMSLIGTPSEQQVADTWLASMQDVLTVQDQSKIPELNEYQCGTYLMHSLAEAQQIAQNVLARKVAVNKNEELTL
DEGLLNA

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=161, Percent_Identity=80.7453416149068, Blast_Score=284, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18754; Mature: 18623

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFKVDHTRMYAPAVRVAKTMTTPKGDTITVFDLRFCVPNKEILPEKGIHTLEHLF
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
AGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPSEQQVADTWLASMQDVLTVQDQSKI
HHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHCC
PELNEYQCGTYLMHSLAEAQQIAQNVLARKVAVNKNEELTLDEGLLNA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
>Mature Secondary Structure 
PLLDSFKVDHTRMYAPAVRVAKTMTTPKGDTITVFDLRFCVPNKEILPEKGIHTLEHLF
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
AGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPSEQQVADTWLASMQDVLTVQDQSKI
HHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHCC
PELNEYQCGTYLMHSLAEAQQIAQNVLARKVAVNKNEELTLDEGLLNA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA