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The map label for this gene is ycbL [H]

Identifier: 161869143

GI number: 161869143

Start: 138716

End: 139348

Strand: Reverse

Name: ycbL [H]

Synonym: NMCC_0137

Alternate gene names: 161869143

Gene position: 139348-138716 (Counterclockwise)

Preceding gene: 161869149

Following gene: 161869137

Centisome position: 6.47

GC content: 57.19

Gene sequence:

>633_bases
ATGACCCTACGTTACGAAATCTTCCCCGTTACCCCCTTCCGCCAAAACTGCACCCTGATTTGGGACGACGAAAGCGGCGA
AGCCGTCCTGACCGATGTCGGCGGCGACGTGCCGTTCCTGCTGCAAGCGTTGGCAAACCGCAAACTTACGCTCACGGCAA
TCTGGCTGACGCACGGCCATCTCGATCACGCGGGCGGCGTGGTCGAAATGTTGAAAACGCATAAAGTCCCTGTCCTCGGG
CCGCATCCGGACGATGAATTCCTGCTCCAATCGCTGCCGCAAACCACCGCGCAATACGGATTCCCCGTCTCGCCCGCCTT
TGCGCCGAACCATTGGCTCGAAGAAGGCGAAACGCTCAAAGTCGGACGCTACGCCTTCCAAGTGCTGCATATTCCGGGGC
ACACGCCGGGACACGTGGTTTTCTATTGTGCCGAAGCGGAGCTGCTGATTGCGGGCGACGTGCTGTTTTACGAAACCATA
GGCAGAACCGATTTTCCGCGCGGCAACCACGCCGACTTAATCAATAATATCCGCAACAAATTATTCGCCCTCCCCGAAAC
CGTGCAAGTTGTCGCCGGACACGGGCGTATGACTTCCATCGGACACGAAAAACGGCACAATCCGTTTTTCTAA

Upstream 100 bases:

>100_bases
CTTAATCATCTGATTCCCCCAATATCAAAACGGGCGGCAAACCGCCATAAAACAAACGGCAAACCCGATGCCGTCTGAAA
AACCGTTTAGGAACACGCCG

Downstream 100 bases:

>100_bases
CCGACTTCACTACGGTCTTCAGACGGCGTCATCTGCACTGATGCCGTCTGAAACGCAAAAGGCTCAGACAACCGCCGCCT
TGCCGGTGTACCTCGCCAGA

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTLRYEIFPVTPFRQNCTLIWDDESGEAVLTDVGGDVPFLLQALANRKLTLTAIWLTHGHLDHAGGVVEMLKTHKVPVLG
PHPDDEFLLQSLPQTTAQYGFPVSPAFAPNHWLEEGETLKVGRYAFQVLHIPGHTPGHVVFYCAEAELLIAGDVLFYETI
GRTDFPRGNHADLINNIRNKLFALPETVQVVAGHGRMTSIGHEKRHNPFF

Sequences:

>Translated_210_residues
MTLRYEIFPVTPFRQNCTLIWDDESGEAVLTDVGGDVPFLLQALANRKLTLTAIWLTHGHLDHAGGVVEMLKTHKVPVLG
PHPDDEFLLQSLPQTTAQYGFPVSPAFAPNHWLEEGETLKVGRYAFQVLHIPGHTPGHVVFYCAEAELLIAGDVLFYETI
GRTDFPRGNHADLINNIRNKLFALPETVQVVAGHGRMTSIGHEKRHNPFF
>Mature_209_residues
TLRYEIFPVTPFRQNCTLIWDDESGEAVLTDVGGDVPFLLQALANRKLTLTAIWLTHGHLDHAGGVVEMLKTHKVPVLGP
HPDDEFLLQSLPQTTAQYGFPVSPAFAPNHWLEEGETLKVGRYAFQVLHIPGHTPGHVVFYCAEAELLIAGDVLFYETIG
RTDFPRGNHADLINNIRNKLFALPETVQVVAGHGRMTSIGHEKRHNPFF

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=201, Percent_Identity=30.3482587064677, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787158, Length=208, Percent_Identity=47.5961538461538, Blast_Score=214, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17538952, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330176, Length=200, Percent_Identity=28, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23438; Mature: 23307

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRYEIFPVTPFRQNCTLIWDDESGEAVLTDVGGDVPFLLQALANRKLTLTAIWLTHGH
CCEEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEEEECCC
LDHAGGVVEMLKTHKVPVLGPHPDDEFLLQSLPQTTAQYGFPVSPAFAPNHWLEEGETLK
CCCCCHHHHHHHHCCCCEECCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCHHHCCCCEEE
VGRYAFQVLHIPGHTPGHVVFYCAEAELLIAGDVLFYETIGRTDFPRGNHADLINNIRNK
EEEEEEEEEECCCCCCCEEEEEEECCEEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHH
LFALPETVQVVAGHGRMTSIGHEKRHNPFF
HHCCCCCEEEEECCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
TLRYEIFPVTPFRQNCTLIWDDESGEAVLTDVGGDVPFLLQALANRKLTLTAIWLTHGH
CEEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEEEECCC
LDHAGGVVEMLKTHKVPVLGPHPDDEFLLQSLPQTTAQYGFPVSPAFAPNHWLEEGETLK
CCCCCHHHHHHHHCCCCEECCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCHHHCCCCEEE
VGRYAFQVLHIPGHTPGHVVFYCAEAELLIAGDVLFYETIGRTDFPRGNHADLINNIRNK
EEEEEEEEEECCCCCCCEEEEEEECCEEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHH
LFALPETVQVVAGHGRMTSIGHEKRHNPFF
HHCCCCCEEEEECCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]