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The map label for this gene is obgE [H]

Identifier: 161869109

GI number: 161869109

Start: 100868

End: 102022

Strand: Direct

Name: obgE [H]

Synonym: NMCC_0100

Alternate gene names: 161869109

Gene position: 100868-102022 (Clockwise)

Preceding gene: 161869106

Following gene: 161869110

Centisome position: 4.68

GC content: 57.4

Gene sequence:

>1155_bases
ATGAAATTCATCGACGAAGCAAAAATCGAAGTCGCCGCAGGCAAAGGCGGTAATGGCGCAACCAGTTTCCGCCGCGAAAA
ATTCGTACCGCGCGGCGGCCCGGACGGCGGCGACGGCGGCAAAGGCGGTAGCGTCTGGGCGGAAGCCGACGAAAACACCA
ACACCCTCGTCGAATACCGCTTCGTTAAACGCTACCAAGCCAAAAACGGCGAAAAAGGCCACGGTTCCGACCGTTACGGC
GCAGGTGCGGACGACATCGTCCTCAAAATGCCCGTCGGCACCCTTATCCGCGACCTCGACACCGACGAAATCGTTGCCGA
CCTCACTTACCACGGACAGCGCGTCTGCCTAGCCAAAGGCGGCAAAGGCGGCTTGGGGCACATCCACTTCAAATCCTCCG
TCAACCGCGCCCCAAAACAATCCACGCCCGGCGAAGAAGGCGAAACCCGCTCCCTGCAACTCGAACTCAAAGTCCTCGCC
GATGTCGGCTTATTAGGCATGCCCAACGCCGGCAAATCCACCCTGATTACCGCCGTATCCGCCGCACGCCCCAAAATCGC
CAACTACCCCTTCACCACCCTGCATCCGAACTTGGGCGTGGTACGCATCGACGAAAACCACAGCTTCGTGATGGCCGACA
TCCCCGGCCTGATTGAAGGCGCGGCAGAAGGCGCGGGTTTGGGGCATCGTTTCCTCAAACACTTATCGCGCACCGGATTA
TTGCTGCACGTCGTCGATTTGGCGCCCTTCGACGAAGCCGTCGATCCCGCCGAAGAAGCCCTTGCCATCATCAACGAATT
ACGCAAATACGATGAAGAACTCTATGGCAAACCGCGCTGGCTGGTGCTGAACAAACTCGACATGCTCGATGAAGAAGAAG
CCCAAGAACGCACCGTCACCTTCCTCGAAGCCGTCGGCTGGGATTACCCGAAACCGGACGACCGCTTCCAATTCGATATG
GAAACCCCGCGCCTCTTCCAAATCAGCGCGCTAACCCACCAAGGCACGCAGGAATTGGTACACCAAATCAACCAATACCT
GACCGAGAAAAAACGCTTGGAAGCCGAAAAAGCAGAAGCGGAGAAAGCGGCGGCAAATGTTGAAATTATCGAACAGCAGC
CTAAAACGGATACGGGCGTGTTTAAGCCGGAGTGA

Upstream 100 bases:

>100_bases
TATCCCTTATAATAGCGTCCGAAATTCTGTTCGGACGGCATCAAAACACATGGTAATCCGTCTGAACCCCCCATTTGAAA
CCAACAAACAAGAGCATTGA

Downstream 100 bases:

>100_bases
AAAAAGAAAGGGTTTCAGACGATATTTGTTCTACAAAAGGTTGTTTGAAACAATTTTAAAGCAAGATTGAAATGGATTAA
AAATGTCATCTAACCAATAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGSVWAEADENTNTLVEYRFVKRYQAKNGEKGHGSDRYG
AGADDIVLKMPVGTLIRDLDTDEIVADLTYHGQRVCLAKGGKGGLGHIHFKSSVNRAPKQSTPGEEGETRSLQLELKVLA
DVGLLGMPNAGKSTLITAVSAARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLIEGAAEGAGLGHRFLKHLSRTGL
LLHVVDLAPFDEAVDPAEEALAIINELRKYDEELYGKPRWLVLNKLDMLDEEEAQERTVTFLEAVGWDYPKPDDRFQFDM
ETPRLFQISALTHQGTQELVHQINQYLTEKKRLEAEKAEAEKAAANVEIIEQQPKTDTGVFKPE

Sequences:

>Translated_384_residues
MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGSVWAEADENTNTLVEYRFVKRYQAKNGEKGHGSDRYG
AGADDIVLKMPVGTLIRDLDTDEIVADLTYHGQRVCLAKGGKGGLGHIHFKSSVNRAPKQSTPGEEGETRSLQLELKVLA
DVGLLGMPNAGKSTLITAVSAARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLIEGAAEGAGLGHRFLKHLSRTGL
LLHVVDLAPFDEAVDPAEEALAIINELRKYDEELYGKPRWLVLNKLDMLDEEEAQERTVTFLEAVGWDYPKPDDRFQFDM
ETPRLFQISALTHQGTQELVHQINQYLTEKKRLEAEKAEAEKAAANVEIIEQQPKTDTGVFKPE
>Mature_384_residues
MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGSVWAEADENTNTLVEYRFVKRYQAKNGEKGHGSDRYG
AGADDIVLKMPVGTLIRDLDTDEIVADLTYHGQRVCLAKGGKGGLGHIHFKSSVNRAPKQSTPGEEGETRSLQLELKVLA
DVGLLGMPNAGKSTLITAVSAARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLIEGAAEGAGLGHRFLKHLSRTGL
LLHVVDLAPFDEAVDPAEEALAIINELRKYDEELYGKPRWLVLNKLDMLDEEEAQERTVTFLEAVGWDYPKPDDRFQFDM
ETPRLFQISALTHQGTQELVHQINQYLTEKKRLEAEKAEAEKAAANVEIIEQQPKTDTGVFKPE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=286, Percent_Identity=41.2587412587413, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI111955139, Length=370, Percent_Identity=34.3243243243243, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI111955063, Length=225, Percent_Identity=36, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI58761500, Length=137, Percent_Identity=32.1167883211679, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1789574, Length=359, Percent_Identity=55.4317548746518, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1787454, Length=132, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=303, Percent_Identity=38.9438943894389, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=348, Percent_Identity=30.1724137931034, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=33.8129496402878, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=191, Percent_Identity=39.2670157068063, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24585318, Length=388, Percent_Identity=33.7628865979381, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI20129375, Length=293, Percent_Identity=41.6382252559727, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=33.5820895522388, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=33.5820895522388, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=33.5820895522388, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42110; Mature: 42110

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGSVWAEADENTNTLVEYR
CCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHH
FVKRYQAKNGEKGHGSDRYGAGADDIVLKMPVGTLIRDLDTDEIVADLTYHGQRVCLAKG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCHHHHHHHHHHCCCEEEEEEC
GKGGLGHIHFKSSVNRAPKQSTPGEEGETRSLQLELKVLADVGLLGMPNAGKSTLITAVS
CCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHH
AARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLIEGAAEGAGLGHRFLKHLSRTGL
HCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHCCE
LLHVVDLAPFDEAVDPAEEALAIINELRKYDEELYGKPRWLVLNKLDMLDEEEAQERTVT
EEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHHHHH
FLEAVGWDYPKPDDRFQFDMETPRLFQISALTHQGTQELVHQINQYLTEKKRLEAEKAEA
HHHHHCCCCCCCCCCEEEECCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKAAANVEIIEQQPKTDTGVFKPE
HHHHCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGSVWAEADENTNTLVEYR
CCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHH
FVKRYQAKNGEKGHGSDRYGAGADDIVLKMPVGTLIRDLDTDEIVADLTYHGQRVCLAKG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCHHHHHHHHHHCCCEEEEEEC
GKGGLGHIHFKSSVNRAPKQSTPGEEGETRSLQLELKVLADVGLLGMPNAGKSTLITAVS
CCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHH
AARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLIEGAAEGAGLGHRFLKHLSRTGL
HCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHCCE
LLHVVDLAPFDEAVDPAEEALAIINELRKYDEELYGKPRWLVLNKLDMLDEEEAQERTVT
EEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHHHHH
FLEAVGWDYPKPDDRFQFDMETPRLFQISALTHQGTQELVHQINQYLTEKKRLEAEKAEA
HHHHHCCCCCCCCCCEEEECCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKAAANVEIIEQQPKTDTGVFKPE
HHHHCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA