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The map label for this gene is gltS [H]

Identifier: 161869103

GI number: 161869103

Start: 93526

End: 94740

Strand: Direct

Name: gltS [H]

Synonym: NMCC_0093

Alternate gene names: 161869103

Gene position: 93526-94740 (Clockwise)

Preceding gene: 161869102

Following gene: 161869104

Centisome position: 4.34

GC content: 53.42

Gene sequence:

>1215_bases
ATGGAATGGGAATTCAACAGTTATTACACACTGATTGCCGCCACGCTCGTGTTGCTGGTTGGTAAATTTCTGGTTCAAAA
AATCAAATTCTTACGAGACTTCAATATTCCCGAGCCGGTCGCTGGCGGTTTGGTTGCCGCGATTATCCTGTTTGCGCTGC
ACGAGGCGTACGGCGTGAGCTTCAAATTTGAGAAACCGCTGCAAAATGCGTTTATGCTGATTTTCTTCACGTCCATCGGC
TTGAGCGCGGATTTTTCCCGTTTGAAGGCGGGCGGTTTGCCGCTGGTGGTTTTTACCGCGATTGTGGGCGGATTTATCTT
GGTGCAAAACTTTGTCGGGGTCGGACTGGCTACGGCTTTGGGTTTGGACCCGCTCATCGGTCTGATTACCGGTTCGGTGT
CGCTGACGGGCGGACACGGTACGTCAGGTGCGTGGGGACCTAATTTTGAAACGCAATACGGCTTGGTCGGCGCAACCGGT
TTGGGTATTGCATCGGCTACTTTCGGGCTGGTGTTCGGCGGCCTGATCGGCGGGCCGGTTGCGCGCCGCCTGATCAACAA
AATGGGCCGCAAACCGGTTGAAAACAAAAAACAGGATCAGGACGACAACGCGGACGACGTGTTCGAGCAGGCAAAACGCA
CCCGCCTGATTACGGCGGAATCTGCCGTTGAAACGCTTGCCATGTTTGCCGCGTGTTTGGCGTTTGCCGAGATTATGGAC
GGCTTCGACAAAGAATATCTGTTCGACCTGCCCAAATTCGTGTGGTGTCTGTTTGGCGGCGTGGTCATCCGCAACATCCT
CACTGCCGCATTCAAGGTCAATATGTTCGACCGCGCCATCGATGTGTTCGGCAATGCTTCGCTTTCGCTTTTCTTGGCAA
TGGCGTTGCTGAATTTGAAACTGTGGGAGCTGACCGGTTTGGCGGGGCCTGTAACCGTGATTCTTGCCGTACAAACCGTG
GTGATGGTTTTGTACGCGACTTTTGTTACCTATGTCTTTATGGGGCGCGACTATGATGCGGCAGTATTGGCTGCCGGCCA
TTGCGGTTTCGGCTTGGGTGCAACGCCGACGGCGGTGGCAAATATGCAGTCCGTCACGCATACTTTCGGCGCGTCGCATA
AGGCGTTTTTGATTGTGCCTATGGTCGGCGCGTTCTTCGTCGATTTGATTAATGCCGCGATTCTCACCGGTTTTGTGAAT
TTCTTTAAAGGCTGA

Upstream 100 bases:

>100_bases
CAATACCATGACACTCGGCGGATAACGCCAAGCGTTGAAACACACTACATCCGGAACAAAAACGGATGCTCGGAAAAATA
TTTCTAGGAGGTGAAACAAC

Downstream 100 bases:

>100_bases
TTTTCCGCCTTTCCGACAAAGCACCTGCAAGGTTTACCGCCTGCAGGTGCTTTTGCTATGATAGCCGCTATCGGTCTGCA
CCGTTTGGAAGGAACATCAT

Product: sodium/glutamate symport carrier protein

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MEWEFNSYYTLIAATLVLLVGKFLVQKIKFLRDFNIPEPVAGGLVAAIILFALHEAYGVSFKFEKPLQNAFMLIFFTSIG
LSADFSRLKAGGLPLVVFTAIVGGFILVQNFVGVGLATALGLDPLIGLITGSVSLTGGHGTSGAWGPNFETQYGLVGATG
LGIASATFGLVFGGLIGGPVARRLINKMGRKPVENKKQDQDDNADDVFEQAKRTRLITAESAVETLAMFAACLAFAEIMD
GFDKEYLFDLPKFVWCLFGGVVIRNILTAAFKVNMFDRAIDVFGNASLSLFLAMALLNLKLWELTGLAGPVTVILAVQTV
VMVLYATFVTYVFMGRDYDAAVLAAGHCGFGLGATPTAVANMQSVTHTFGASHKAFLIVPMVGAFFVDLINAAILTGFVN
FFKG

Sequences:

>Translated_404_residues
MEWEFNSYYTLIAATLVLLVGKFLVQKIKFLRDFNIPEPVAGGLVAAIILFALHEAYGVSFKFEKPLQNAFMLIFFTSIG
LSADFSRLKAGGLPLVVFTAIVGGFILVQNFVGVGLATALGLDPLIGLITGSVSLTGGHGTSGAWGPNFETQYGLVGATG
LGIASATFGLVFGGLIGGPVARRLINKMGRKPVENKKQDQDDNADDVFEQAKRTRLITAESAVETLAMFAACLAFAEIMD
GFDKEYLFDLPKFVWCLFGGVVIRNILTAAFKVNMFDRAIDVFGNASLSLFLAMALLNLKLWELTGLAGPVTVILAVQTV
VMVLYATFVTYVFMGRDYDAAVLAAGHCGFGLGATPTAVANMQSVTHTFGASHKAFLIVPMVGAFFVDLINAAILTGFVN
FFKG
>Mature_404_residues
MEWEFNSYYTLIAATLVLLVGKFLVQKIKFLRDFNIPEPVAGGLVAAIILFALHEAYGVSFKFEKPLQNAFMLIFFTSIG
LSADFSRLKAGGLPLVVFTAIVGGFILVQNFVGVGLATALGLDPLIGLITGSVSLTGGHGTSGAWGPNFETQYGLVGATG
LGIASATFGLVFGGLIGGPVARRLINKMGRKPVENKKQDQDDNADDVFEQAKRTRLITAESAVETLAMFAACLAFAEIMD
GFDKEYLFDLPKFVWCLFGGVVIRNILTAAFKVNMFDRAIDVFGNASLSLFLAMALLNLKLWELTGLAGPVTVILAVQTV
VMVLYATFVTYVFMGRDYDAAVLAAGHCGFGLGATPTAVANMQSVTHTFGASHKAFLIVPMVGAFFVDLINAAILTGFVN
FFKG

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=375, Percent_Identity=51.2, Blast_Score=330, Evalue=9e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43186; Mature: 43186

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]