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The map label for this gene is synX [H]

Identifier: 161869089

GI number: 161869089

Start: 75820

End: 76974

Strand: Reverse

Name: synX [H]

Synonym: NMCC_0078

Alternate gene names: 161869089

Gene position: 76974-75820 (Counterclockwise)

Preceding gene: 161869107

Following gene: 161869088

Centisome position: 3.57

GC content: 37.84

Gene sequence:

>1155_bases
ATGCCTATAGATTCTAAAATCATGAAAAGAATTCTTTGCATTACAGGTACCAGAGCCGACTTCGGCAAGCTAAAACCTTT
ATTAGCCTATATTGAAAATCACCCAGACCTTGAATTGCATTTGATTGTAACTGGTATGCATATGATGAAAACATATGGCA
GAACCTGCAAGGAAGTAACTCGAGAAAACTATCAACATACATATCTGTTTTCAAATCAAATCCAAGGTGAACCAATGGGT
GCCGTTTTAGGCAATACCATTACGTTTATCTCTCGTCTATCTGATGAAATTGAACCTGATATGGTCATGATTCACGGCGA
CCGTTTAGAAGCACTAGCAGGCGCAACTGTAGGTGCATTAAGCAGCCGTTTAGTTTGCCATATCGAAGGTGGTGAACTAT
CTGGTACAGTAGATGACTCCATTCGTCATTCTATTAGTAAACTTTCTCATATCCACTTGGTAGCAAATGAACAAGCTGTC
ACTCGCCTAGTGCAAATGGGAGAAAAAAGAAAGCATATTCACATCATCGGCTCCCCCGATTTAGATGTTATGGCCTCTTC
CACCCTCCCATCCTTAGAAGAAGTCAAAGAATATTACGGTTTACCATACGAAAATTATGGTATTTCTATGTTTCACCCCG
TGACTACAGAAGCACATTTAATGCCACAATATGCGGCCCAATATTTCAAAGCATTAGAATTAAGTGGCCAAAATATCATT
AGCATCTACCCTAATAATGACACTGGCACTGAAAGTATTCTGCAAGAATTATTAAAATATCAATCTGATAAATTTATTGC
ATTTCCTTCCATTCGATTTGAATATTTTTTAGTCTTATTGAAACATGCTAAATTTATGGTCGGCAACTCAAGTGCAGGTA
TTAGAGAAGCTCCTCTCTACGGTGTCCCTTCAATTGATGTTGGTACACGCCAAAGTAACCGCCATATGGGAAAATCTATT
ATTCATACAGATTATGAAACTAAAAATATCTTTGATGCGATTCAACAAGCATGCAGTTTAGGCAAATTTGAAGCAGATGA
TACCTTTAATGGCGGAGATACTCGCACCAGCACAGAAAGATTTGCTGAAGTAATCAACAATCCTGAAACGTGGAATGTTT
CTGCTCAAAAACGTTTTATCGATTTGAATCTTTAA

Upstream 100 bases:

>100_bases
ATTATAAATGGCCTAATTATAGCACTTAATCGAAATAAATTTATGAGTACGTAGAGTATAATTAGGGACACGCCCTAGTA
TTCTTCTTTCCAACTTCCTT

Downstream 100 bases:

>100_bases
ATTATGGAAAAACAAAATATTGCGGTTATACTTGCGCGCCAAAACTCCAAAGGATTGCCATTAAAAAATCTCCGGAAAAT
GAATGGCATATCATTACTTG

Product: polysialic acid capsule biosynthesis protein SynX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MPIDSKIMKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKTYGRTCKEVTRENYQHTYLFSNQIQGEPMG
AVLGNTITFISRLSDEIEPDMVMIHGDRLEALAGATVGALSSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAV
TRLVQMGEKRKHIHIIGSPDLDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYAAQYFKALELSGQNII
SIYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHAKFMVGNSSAGIREAPLYGVPSIDVGTRQSNRHMGKSI
IHTDYETKNIFDAIQQACSLGKFEADDTFNGGDTRTSTERFAEVINNPETWNVSAQKRFIDLNL

Sequences:

>Translated_384_residues
MPIDSKIMKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKTYGRTCKEVTRENYQHTYLFSNQIQGEPMG
AVLGNTITFISRLSDEIEPDMVMIHGDRLEALAGATVGALSSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAV
TRLVQMGEKRKHIHIIGSPDLDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYAAQYFKALELSGQNII
SIYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHAKFMVGNSSAGIREAPLYGVPSIDVGTRQSNRHMGKSI
IHTDYETKNIFDAIQQACSLGKFEADDTFNGGDTRTSTERFAEVINNPETWNVSAQKRFIDLNL
>Mature_383_residues
PIDSKIMKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKTYGRTCKEVTRENYQHTYLFSNQIQGEPMGA
VLGNTITFISRLSDEIEPDMVMIHGDRLEALAGATVGALSSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAVT
RLVQMGEKRKHIHIIGSPDLDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYAAQYFKALELSGQNIIS
IYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHAKFMVGNSSAGIREAPLYGVPSIDVGTRQSNRHMGKSII
HTDYETKNIFDAIQQACSLGKFEADDTFNGGDTRTSTERFAEVINNPETWNVSAQKRFIDLNL

Specific function: May be involved in the synthesis of polysialic acid (PSA) [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI298566312, Length=384, Percent_Identity=30.9895833333333, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI4885285, Length=384, Percent_Identity=30.9895833333333, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI190014632, Length=384, Percent_Identity=30.9895833333333, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI298566325, Length=395, Percent_Identity=29.1139240506329, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI298566315, Length=313, Percent_Identity=30.3514376996805, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020004
- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: NA

Molecular weight: Translated: 43064; Mature: 42933

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDSKIMKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKTYGRTCKEVT
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHH
RENYQHTYLFSNQIQGEPMGAVLGNTITFISRLSDEIEPDMVMIHGDRLEALAGATVGAL
HCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCHHHHH
SSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAVTRLVQMGEKRKHIHIIGSPD
CCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEEECHHHHHHHHHHCCCCCEEEEECCCC
LDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYAAQYFKALELSGQNII
HHEEECCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEE
SIYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHAKFMVGNSSAGIREAPLY
EEECCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCC
GVPSIDVGTRQSNRHMGKSIIHTDYETKNIFDAIQQACSLGKFEADDTFNGGDTRTSTER
CCCCCCCCCCCCCHHHCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
FAEVINNPETWNVSAQKRFIDLNL
HHHHHCCCCCCCCCHHEEEEEECC
>Mature Secondary Structure 
PIDSKIMKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKTYGRTCKEVT
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHH
RENYQHTYLFSNQIQGEPMGAVLGNTITFISRLSDEIEPDMVMIHGDRLEALAGATVGAL
HCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCHHHHH
SSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAVTRLVQMGEKRKHIHIIGSPD
CCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEEECHHHHHHHHHHCCCCCEEEEECCCC
LDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYAAQYFKALELSGQNII
HHEEECCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEE
SIYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHAKFMVGNSSAGIREAPLY
EEECCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCC
GVPSIDVGTRQSNRHMGKSIIHTDYETKNIFDAIQQACSLGKFEADDTFNGGDTRTSTER
CCCCCCCCCCCCCHHHCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
FAEVINNPETWNVSAQKRFIDLNL
HHHHHCCCCCCCCCHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1729218 [H]