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The map label for this gene is glmU [H]

Identifier: 161869056

GI number: 161869056

Start: 34004

End: 35374

Strand: Reverse

Name: glmU [H]

Synonym: NMCC_0039

Alternate gene names: 161869056

Gene position: 35374-34004 (Counterclockwise)

Preceding gene: 161869057

Following gene: 161869055

Centisome position: 1.64

GC content: 57.77

Gene sequence:

>1371_bases
ATGCCGCAAAACACTTTAAACATCGTTATCCTCGCCGCCGGCAAAGGCACGCGCATGTATTCCAAAATGCCCAAAGTGCT
GCACCGCATCGGCGGCAAGCCCATGCTCGGGCGCGTTATCGACACCGCCGCCGCGCTGAATCCGCAAAACATCTGCGTCG
TCGTCGGCCACGGCAAAGAGCAAGTTTTAGACACCGTCAAACGCGATGTCGTTTGGGTCGAACAAACCGAACAGCTCGGC
ACCGGCCACGCCGTCAAAACCGCCCTGCCCCACCTTGCCGCCGAAGGCCGCACGCTGGTGCTGTACGGCGACGTTCCTTT
AATTGACGTTGAAACCCTCAAAACCCTGCTCGAAGCCGCAGGCGACAAAGTCGGGCTGTTGACTGATGTTCCCACCGACC
CGACAGGCTTGGGGCGCATCATCCGCGACGGCAACGGCAGCGTAACCGCCATTGTCGAAGAAAAAGACGCAAGTACCGCC
CAAAAAGCCGTGAAAGAAACCAACACAGGCATTCTCGTCCTGCCCAACGCCAAACTGGAAAACTGGCTGAACAGCCTTTC
CAGCAACAATGCCCAAGGCGAATACTATCTGACCGACCTCATCGCCAAAGCCGTTTCAGACGGCATCAAAGTCCGCCCCG
TCCGAGTGCGCGCCTCTCACCTCGCCGCCGGCGTGAACAACAAACTCCAGCTCGCCGAACTCGAACGCATCTTCCAAACC
GGACAGGCGCAAGAATTGCTCAAAGCAGGCGTTACCCTGCACGACCCGGCACGTTTCGATTTGCGGGGCCGTCTGAAACA
CGGGCAAGATGTCGTGATTGATGCAAACTGTATCTTTGAAGGCGAAATCGAGCTCGGCGACAACGTCGAAATCGGCGCAA
GCTGCGTCATCAAAAACGCCAAAATCGGTGCCAACACCAAAATCGCCCCCTTCTCCCACCTCGAAGACTGCGAAGTCGGC
GAAAACAACCGAATCGGCCCGTACGCCCGCCTGCGTCCGCAAGCCCGCCTTGCAGACGACGTACACGTCGGCAACTTCGT
CGAAATCAAAAACGCCGCCATCGGCAAAGGCACCAAAGCCAACCACCTCACCTACATTGGTGATGCCGAAGTCGGCAGCA
AAACCAACTTCGGCGCAGGTACGATTATTGCCAACTACGACGGCGTGCACAAACACAAAACCGTCATCGGCAACGAAGTG
CGCATCGGTTCAAACTGCGTACTGGTTGCCCCCGTTACCCTCGGCAACAAAGTAACCACAGGCGCAGGCAGCGCGATTAC
CCGCAACGTCGAAGACGGCAAACTCGCCCTCGCCCGCGCCCGCCAAACCGTCATCGAAGGCTGGGTGAGGCCGGAAAAAG
ACAAACAATAA

Upstream 100 bases:

>100_bases
CGTACGCGGACAGAACTGGCAAAAGCCCAAATTTCAAAACCGATAAACCCACCCTATGCCGTCTGAAGCTGCTTCAGACG
GCATTGCACAGGAAACCGTC

Downstream 100 bases:

>100_bases
AGCCATGCCGTCTGAAGCCGGTTTCAGGTTTCAGACGGCATCAAACCCCTCCGATATCAGATAAGGACTGCAAACCATGT
CATTACCCCCATGCCCACAA

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MPQNTLNIVILAAGKGTRMYSKMPKVLHRIGGKPMLGRVIDTAAALNPQNICVVVGHGKEQVLDTVKRDVVWVEQTEQLG
TGHAVKTALPHLAAEGRTLVLYGDVPLIDVETLKTLLEAAGDKVGLLTDVPTDPTGLGRIIRDGNGSVTAIVEEKDASTA
QKAVKETNTGILVLPNAKLENWLNSLSSNNAQGEYYLTDLIAKAVSDGIKVRPVRVRASHLAAGVNNKLQLAELERIFQT
GQAQELLKAGVTLHDPARFDLRGRLKHGQDVVIDANCIFEGEIELGDNVEIGASCVIKNAKIGANTKIAPFSHLEDCEVG
ENNRIGPYARLRPQARLADDVHVGNFVEIKNAAIGKGTKANHLTYIGDAEVGSKTNFGAGTIIANYDGVHKHKTVIGNEV
RIGSNCVLVAPVTLGNKVTTGAGSAITRNVEDGKLALARARQTVIEGWVRPEKDKQ

Sequences:

>Translated_456_residues
MPQNTLNIVILAAGKGTRMYSKMPKVLHRIGGKPMLGRVIDTAAALNPQNICVVVGHGKEQVLDTVKRDVVWVEQTEQLG
TGHAVKTALPHLAAEGRTLVLYGDVPLIDVETLKTLLEAAGDKVGLLTDVPTDPTGLGRIIRDGNGSVTAIVEEKDASTA
QKAVKETNTGILVLPNAKLENWLNSLSSNNAQGEYYLTDLIAKAVSDGIKVRPVRVRASHLAAGVNNKLQLAELERIFQT
GQAQELLKAGVTLHDPARFDLRGRLKHGQDVVIDANCIFEGEIELGDNVEIGASCVIKNAKIGANTKIAPFSHLEDCEVG
ENNRIGPYARLRPQARLADDVHVGNFVEIKNAAIGKGTKANHLTYIGDAEVGSKTNFGAGTIIANYDGVHKHKTVIGNEV
RIGSNCVLVAPVTLGNKVTTGAGSAITRNVEDGKLALARARQTVIEGWVRPEKDKQ
>Mature_455_residues
PQNTLNIVILAAGKGTRMYSKMPKVLHRIGGKPMLGRVIDTAAALNPQNICVVVGHGKEQVLDTVKRDVVWVEQTEQLGT
GHAVKTALPHLAAEGRTLVLYGDVPLIDVETLKTLLEAAGDKVGLLTDVPTDPTGLGRIIRDGNGSVTAIVEEKDASTAQ
KAVKETNTGILVLPNAKLENWLNSLSSNNAQGEYYLTDLIAKAVSDGIKVRPVRVRASHLAAGVNNKLQLAELERIFQTG
QAQELLKAGVTLHDPARFDLRGRLKHGQDVVIDANCIFEGEIELGDNVEIGASCVIKNAKIGANTKIAPFSHLEDCEVGE
NNRIGPYARLRPQARLADDVHVGNFVEIKNAAIGKGTKANHLTYIGDAEVGSKTNFGAGTIIANYDGVHKHKTVIGNEVR
IGSNCVLVAPVTLGNKVTTGAGSAITRNVEDGKLALARARQTVIEGWVRPEKDKQ

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=457, Percent_Identity=53.1728665207877, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 48754; Mature: 48623

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQNTLNIVILAAGKGTRMYSKMPKVLHRIGGKPMLGRVIDTAAALNPQNICVVVGHGKE
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCHH
QVLDTVKRDVVWVEQTEQLGTGHAVKTALPHLAAEGRTLVLYGDVPLIDVETLKTLLEAA
HHHHHHHHCEEEEECHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHHHHHC
GDKVGLLTDVPTDPTGLGRIIRDGNGSVTAIVEEKDASTAQKAVKETNTGILVLPNAKLE
CCCEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCHHH
NWLNSLSSNNAQGEYYLTDLIAKAVSDGIKVRPVRVRASHLAAGVNNKLQLAELERIFQT
HHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCHHHHHHHHHHC
GQAQELLKAGVTLHDPARFDLRGRLKHGQDVVIDANCIFEGEIELGDNVEIGASCVIKNA
CCHHHHHHCCCEEECCCCCCEEECCCCCCEEEEEEEEEEEEEEECCCCCEECCEEEEECC
KIGANTKIAPFSHLEDCEVGENNRIGPYARLRPQARLADDVHVGNFVEIKNAAIGKGTKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCCCCCCCEEEECCCCCCCCCCC
NHLTYIGDAEVGSKTNFGAGTIIANYDGVHKHKTVIGNEVRIGSNCVLVAPVTLGNKVTT
CEEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHEECCEEEECCCEEEEEEEECCCEEEC
GAGSAITRNVEDGKLALARARQTVIEGWVRPEKDKQ
CCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PQNTLNIVILAAGKGTRMYSKMPKVLHRIGGKPMLGRVIDTAAALNPQNICVVVGHGKE
CCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCHH
QVLDTVKRDVVWVEQTEQLGTGHAVKTALPHLAAEGRTLVLYGDVPLIDVETLKTLLEAA
HHHHHHHHCEEEEECHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHHHHHC
GDKVGLLTDVPTDPTGLGRIIRDGNGSVTAIVEEKDASTAQKAVKETNTGILVLPNAKLE
CCCEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCHHH
NWLNSLSSNNAQGEYYLTDLIAKAVSDGIKVRPVRVRASHLAAGVNNKLQLAELERIFQT
HHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCHHHHHHHHHHC
GQAQELLKAGVTLHDPARFDLRGRLKHGQDVVIDANCIFEGEIELGDNVEIGASCVIKNA
CCHHHHHHCCCEEECCCCCCEEECCCCCCEEEEEEEEEEEEEEECCCCCEECCEEEEECC
KIGANTKIAPFSHLEDCEVGENNRIGPYARLRPQARLADDVHVGNFVEIKNAAIGKGTKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCCCCCCCEEEECCCCCCCCCCC
NHLTYIGDAEVGSKTNFGAGTIIANYDGVHKHKTVIGNEVRIGSNCVLVAPVTLGNKVTT
CEEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHEECCEEEECCCEEEEEEEECCCEEEC
GAGSAITRNVEDGKLALARARQTVIEGWVRPEKDKQ
CCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA