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The map label for this gene is rpl18p [H]

Identifier: 161777476

GI number: 161777476

Start: 602793

End: 603383

Strand: Reverse

Name: rpl18p [H]

Synonym: SSO0699

Alternate gene names: 161777476

Gene position: 603383-602793 (Counterclockwise)

Preceding gene: 15897606

Following gene: 15897604

Centisome position: 20.16

GC content: 35.7

Gene sequence:

>591_bases
TTGGCCAATGGTCCTAATTATAAGGTAAAACCCAGAAGAAGAAGAGAAGGAAAAACTAACTACTATAAAAGATATGTCTA
TGTTATAAGTAAACAAACAAGGTTTATTGTAAGAATAACAAACAAATACGTTATAGTCCAGATTGCAAAAATCGATCCTA
AAGGCGATATTATGATTGCTAGTGCTCATTCAGCTGAACTTGCTAAAAAGTTCGGATGGAAGGGTGATGAAAATAACACT
CCAGCTGCATACCTGACCGGATATTTAGCAGGCTTAAGAGCTATAAAGAGAGGTGTAACTGAGTGCGTGGCGGATATTGG
GCTTCATGTACCATCTAAGGGTAACAGGGTGTTTTATGTGATAAAAGGTGCAATTGATGCTGGATTGAAAATTCCGATAG
GCGACATAAGTATAGAAAATGATAGAATAAAGGGAGAGCATATAGCAAAGTATGCTGAGAAGTTAAAATCTGAGAATTCG
GACTTATATAGTAAATTGTTTTCAAGGTATTTACAAAGGGGACTAAACCCCGAGAACTTGCCTTCTCATTTTGAGGAAAT
ATTAAATAAGATTAAATCTTCTGGTGGTTAA

Upstream 100 bases:

>100_bases
ACAGGGAATTATACTTAAAAACGAAAGGCGGCAACTATAAGGGAGTTTCTGATGTCAGAAATGTCCTAATACAAATGGGG
AAAATTAAAGGGTGAATAAA

Downstream 100 bases:

>100_bases
AATGGCAGAGGAAGTACCAAGTTTAAATATAGAAGAATGGAAACCACGAACCTCTATAGGTAGTCTAGTAAAGGAAGGAA
AAATATCATCTATAAAGGAA

Product: 50S ribosomal protein L18P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MANGPNYKVKPRRRREGKTNYYKRYVYVISKQTRFIVRITNKYVIVQIAKIDPKGDIMIASAHSAELAKKFGWKGDENNT
PAAYLTGYLAGLRAIKRGVTECVADIGLHVPSKGNRVFYVIKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENS
DLYSKLFSRYLQRGLNPENLPSHFEEILNKIKSSGG

Sequences:

>Translated_196_residues
MANGPNYKVKPRRRREGKTNYYKRYVYVISKQTRFIVRITNKYVIVQIAKIDPKGDIMIASAHSAELAKKFGWKGDENNT
PAAYLTGYLAGLRAIKRGVTECVADIGLHVPSKGNRVFYVIKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENS
DLYSKLFSRYLQRGLNPENLPSHFEEILNKIKSSGG
>Mature_195_residues
ANGPNYKVKPRRRREGKTNYYKRYVYVISKQTRFIVRITNKYVIVQIAKIDPKGDIMIASAHSAELAKKFGWKGDENNTP
AAYLTGYLAGLRAIKRGVTECVADIGLHVPSKGNRVFYVIKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENSD
LYSKLFSRYLQRGLNPENLPSHFEEILNKIKSSGG

Specific function: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [H]

COG id: COG0256

COG function: function code J; Ribosomal protein L18

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L18P family [H]

Homologues:

Organism=Homo sapiens, GI14591909, Length=236, Percent_Identity=31.7796610169492, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17534333, Length=235, Percent_Identity=33.6170212765957, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325126, Length=227, Percent_Identity=30.3964757709251, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI116007384, Length=235, Percent_Identity=31.4893617021277, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI116007382, Length=235, Percent_Identity=31.4893617021277, Blast_Score=106, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005484
- InterPro:   IPR005485 [H]

Pfam domain/function: PF00861 Ribosomal_L18p [H]

EC number: NA

Molecular weight: Translated: 22047; Mature: 21916

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANGPNYKVKPRRRREGKTNYYKRYVYVISKQTRFIVRITNKYVIVQIAKIDPKGDIMIA
CCCCCCCCCCCHHHCCCCHHHHEEEEEEEECCCEEEEEEECCEEEEEEEEECCCCCEEEE
SAHSAELAKKFGWKGDENNTPAAYLTGYLAGLRAIKRGVTECVADIGLHVPSKGNRVFYV
ECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENSDLYSKLFSRYLQRGLNPENL
EEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
PSHFEEILNKIKSSGG
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANGPNYKVKPRRRREGKTNYYKRYVYVISKQTRFIVRITNKYVIVQIAKIDPKGDIMIA
CCCCCCCCCCHHHCCCCHHHHEEEEEEEECCCEEEEEEECCEEEEEEEEECCCCCEEEE
SAHSAELAKKFGWKGDENNTPAAYLTGYLAGLRAIKRGVTECVADIGLHVPSKGNRVFYV
ECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENSDLYSKLFSRYLQRGLNPENL
EEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
PSHFEEILNKIKSSGG
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]