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The map label for this gene is prmA

Identifier: 161760558

GI number: 161760558

Start: 4255840

End: 4256721

Strand: Direct

Name: prmA

Synonym: YPTB3575

Alternate gene names: 161760558

Gene position: 4255840-4256721 (Clockwise)

Preceding gene: 51597865

Following gene: 51597867

Centisome position: 89.7

GC content: 53.06

Gene sequence:

>882_bases
ATGCCTTGGATCCAACTAAAATTAAACACCACCGGCAACCAAGCCGAATCCCTAGGGGACGTTCTGGTAGAAAGTGGTGC
TGTGTCGGTCACTTTTCAGGACACCCACGATAATCCGGTCTTCGAGCCACTGCCTGGTGAAACCCGTCTGTGGGGCGATA
CCGATGTCATTGGCCTGTATGATGCAGAAACCGATATGGCTGACGTGGTCGCCATGTTGGAATGCCACCCGCAGATCGGC
AAAGGCTTTATCCATAAAATTGAACAGTTGGAAGATAAAGATTGGGAGCGTGAATGGATGGATAACTTCCATCCGATGCG
TTTTGGTGAGCGCCTGTGGATCTGCCCAAGCTGGCGTGATGTGCCAGATCCAACGGCGGTTAACGTTATGCTCGACCCCG
GCTTAGCCTTTGGTACGGGTACCCACCCTACCACAGCACTATGCTTACAATGGCTAGATAGCCTCGATCTCAATGGTAAA
ACCCTCATCGATTTCGGTTGTGGCTCTGGCATCCTGGCGATTGCCGCGCTAAAGCTCGGTGCAGCGCGCGCTATTGGCAT
TGATATCGATCCGCAGGCCATTCAAGCCAGTCGCGATAACGCGCAGCGTAACGGCGTTTCAGAGCGTTTGGAGCTGTATC
TGGCAAAAGACCAGCCCGCAGAACTATCTGCTGACGTGGTCGTGGCCAATATTCTGGCAGGCCCATTACGGGAACTGGCA
CTACTGATTAGCGTTTTACCGACGACGGGCGGCCATCTTGGGTTGTCTGGGGTATTAGCAACACAAGCGGCGGGCGTCGC
ACAGGCCTATGAGGATAAATTCATTCTCGACCCAGTCGCCGAGAAAGAAGAATGGTGCCGCATTACCGGTATCAAAAAAT
AA

Upstream 100 bases:

>100_bases
CCCCGCCATCGTCAGTGCCGATTAAAATCACTATTACTCTATCAACACATCAGCCGGTATCGTGGTTATGGCCCCGATAC
CGGCGCTTGAGAGAATTGCT

Downstream 100 bases:

>100_bases
TTTTGCCTTAACTGGCGCACACGGACTTGAGTCCGTGTGCGCCACAACTCACCTTTCAACGCCAGCCACCTTTCATCATC
AACAATCCTTCATCATCAAC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MPWIQLKLNTTGNQAESLGDVLVESGAVSVTFQDTHDNPVFEPLPGETRLWGDTDVIGLYDAETDMADVVAMLECHPQIG
KGFIHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDPTAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLNGK
TLIDFGCGSGILAIAALKLGAARAIGIDIDPQAIQASRDNAQRNGVSERLELYLAKDQPAELSADVVVANILAGPLRELA
LLISVLPTTGGHLGLSGVLATQAAGVAQAYEDKFILDPVAEKEEWCRITGIKK

Sequences:

>Translated_293_residues
MPWIQLKLNTTGNQAESLGDVLVESGAVSVTFQDTHDNPVFEPLPGETRLWGDTDVIGLYDAETDMADVVAMLECHPQIG
KGFIHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDPTAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLNGK
TLIDFGCGSGILAIAALKLGAARAIGIDIDPQAIQASRDNAQRNGVSERLELYLAKDQPAELSADVVVANILAGPLRELA
LLISVLPTTGGHLGLSGVLATQAAGVAQAYEDKFILDPVAEKEEWCRITGIKK
>Mature_292_residues
PWIQLKLNTTGNQAESLGDVLVESGAVSVTFQDTHDNPVFEPLPGETRLWGDTDVIGLYDAETDMADVVAMLECHPQIGK
GFIHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDPTAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLNGKT
LIDFGCGSGILAIAALKLGAARAIGIDIDPQAIQASRDNAQRNGVSERLELYLAKDQPAELSADVVVANILAGPLRELAL
LISVLPTTGGHLGLSGVLATQAAGVAQAYEDKFILDPVAEKEEWCRITGIKK

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=84.641638225256, Blast_Score=474, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31865; Mature: 31733

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQLKLNTTGNQAESLGDVLVESGAVSVTFQDTHDNPVFEPLPGETRLWGDTDVIGLY
CCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMADVVAMLECHPQIGKGFIHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRD
ECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEECCCCCC
VPDPTAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLNGKTLIDFGCGSGILAIAALKLG
CCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHC
AARAIGIDIDPQAIQASRDNAQRNGVSERLELYLAKDQPAELSADVVVANILAGPLRELA
CCEEEECCCCHHHHHCCHHHHHHCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
LLISVLPTTGGHLGLSGVLATQAAGVAQAYEDKFILDPVAEKEEWCRITGIKK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHEEECCCCC
>Mature Secondary Structure 
PWIQLKLNTTGNQAESLGDVLVESGAVSVTFQDTHDNPVFEPLPGETRLWGDTDVIGLY
CEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMADVVAMLECHPQIGKGFIHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRD
ECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEECCCCCC
VPDPTAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLNGKTLIDFGCGSGILAIAALKLG
CCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHC
AARAIGIDIDPQAIQASRDNAQRNGVSERLELYLAKDQPAELSADVVVANILAGPLRELA
CCEEEECCCCHHHHHCCHHHHHHCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
LLISVLPTTGGHLGLSGVLATQAAGVAQAYEDKFILDPVAEKEEWCRITGIKK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA